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Items: 1 to 20 of 67


IL-13-regulated Macrophage Polarization during Granuloma Formation in an In Vitro Human Sarcoidosis Model.

Locke LW, Crouser ED, White P, Julian MW, Caceres EG, Papp AC, Le VT, Sadee W, Schlesinger LS.

Am J Respir Cell Mol Biol. 2019 Jan;60(1):84-95. doi: 10.1165/rcmb.2018-0053OC.


AmpliSeq transcriptome analysis of human alveolar and monocyte-derived macrophages over time in response to Mycobacterium tuberculosis infection.

Papp AC, Azad AK, Pietrzak M, Williams A, Handelman SK, Igo RP Jr, Stein CM, Hartmann K, Schlesinger LS, Sadee W.

PLoS One. 2018 May 30;13(5):e0198221. doi: 10.1371/journal.pone.0198221. eCollection 2018.


Elemental Ingredients in the Macrophage Cocktail: Role of ZIP8 in Host Response to Mycobacterium tuberculosis.

Pyle CJ, Azad AK, Papp AC, Sadee W, Knoell DL, Schlesinger LS.

Int J Mol Sci. 2017 Nov 9;18(11). pii: E2375. doi: 10.3390/ijms18112375. Review.


A Novel In Vitro Human Granuloma Model of Sarcoidosis and Latent Tuberculosis Infection.

Crouser ED, White P, Caceres EG, Julian MW, Papp AC, Locke LW, Sadee W, Schlesinger LS.

Am J Respir Cell Mol Biol. 2017 Oct;57(4):487-498. doi: 10.1165/rcmb.2016-0321OC.


Expression and splicing of ABC and SLC transporters in the human blood-brain barrier measured with RNAseq.

Suhy AM, Webb A, Papp AC, Geier EG, Sadee W.

Eur J Pharm Sci. 2017 May 30;103:47-51. doi: 10.1016/j.ejps.2017.02.010. Epub 2017 Feb 7.


Transcriptomic variation of pharmacogenes in multiple human tissues and lymphoblastoid cell lines.

Chhibber A, French CE, Yee SW, Gamazon ER, Theusch E, Qin X, Webb A, Papp AC, Wang A, Simmons CQ, Konkashbaev A, Chaudhry AS, Mitchel K, Stryke D, Ferrin TE, Weiss ST, Kroetz DL, Sadee W, Nickerson DA, Krauss RM, George AL, Schuetz EG, Medina MW, Cox NJ, Scherer SE, Giacomini KM, Brenner SE.

Pharmacogenomics J. 2017 Mar;17(2):137-145. doi: 10.1038/tpj.2015.93. Epub 2016 Feb 9.


RNA sequencing of transcriptomes in human brain regions: protein-coding and non-coding RNAs, isoforms and alleles.

Webb A, Papp AC, Curtis A, Newman LC, Pietrzak M, Seweryn M, Handelman SK, Rempala GA, Wang D, Graziosa E, Tyndale RF, Lerman C, Kelsoe JR, Mash DC, Sadee W.

BMC Genomics. 2015 Nov 23;16:990. doi: 10.1186/s12864-015-2207-8.


Allele-Selective Transcriptome Recruitment to Polysomes Primed for Translation: Protein-Coding and Noncoding RNAs, and RNA Isoforms.

Mascarenhas R, Pietrzak M, Smith RM, Webb A, Wang D, Papp AC, Pinsonneault JK, Seweryn M, Rempala G, Sadee W.

PLoS One. 2015 Sep 2;10(9):e0136798. doi: 10.1371/journal.pone.0136798. eCollection 2015.


Regulation of cholesteryl ester transfer protein expression by upstream polymorphisms: reduced expression associated with rs247616.

Suhy A, Hartmann K, Papp AC, Wang D, Sadee W.

Pharmacogenet Genomics. 2015 Aug;25(8):394-401. doi: 10.1097/FPC.0000000000000151.


Functional characterization of CYP2D6 enhancer polymorphisms.

Wang D, Papp AC, Sun X.

Hum Mol Genet. 2015 Mar 15;24(6):1556-62. doi: 10.1093/hmg/ddu566. Epub 2014 Nov 7.


Cholesteryl ester transfer protein polymorphisms, statin use, and their impact on cholesterol levels and cardiovascular events.

Leusink M, Onland-Moret NC, Asselbergs FW, Ding B, Kotti S, van Zuydam NR, Papp AC, Danchin N, Donnelly L, Morris AD, Chasman DI, Doevendans PA, Klungel OH, Ridker PM, van Gilst WH, Simon T, Nyberg F, Palmer CN, Sadee W, van der Harst P, de Bakker PI, de Boer A, Verstuyft C, Maitland-van der Zee AH.

Clin Pharmacol Ther. 2014 Mar;95(3):314-20. doi: 10.1038/clpt.2013.194. Epub 2013 Sep 30.


Profiling solute carrier transporters in the human blood-brain barrier.

Geier EG, Chen EC, Webb A, Papp AC, Yee SW, Sadee W, Giacomini KM.

Clin Pharmacol Ther. 2013 Dec;94(6):636-9. doi: 10.1038/clpt.2013.175. Epub 2013 Sep 5.


Whole transcriptome RNA-Seq allelic expression in human brain.

Smith RM, Webb A, Papp AC, Newman LC, Handelman SK, Suhy A, Mascarenhas R, Oberdick J, Sadee W.

BMC Genomics. 2013 Aug 22;14:571. doi: 10.1186/1471-2164-14-571.


Expression of mRNA transcripts encoding membrane transporters detected with whole transcriptome sequencing of human brain and liver.

Webb A, Papp AC, Sanford JC, Huang K, Parvin JD, Sadee W.

Pharmacogenet Genomics. 2013 May;23(5):269-78. doi: 10.1097/FPC.0b013e32835ff536.


Dopamine transporter DAT and receptor DRD2 variants affect risk of lethal cocaine abuse: a gene-gene-environment interaction.

Sullivan D, Pinsonneault JK, Papp AC, Zhu H, Lemeshow S, Mash DC, Sadee W.

Transl Psychiatry. 2013 Jan 22;3:e222. doi: 10.1038/tp.2012.146.


Multiple regulatory variants modulate expression of 5-hydroxytryptamine 2A receptors in human cortex.

Smith RM, Papp AC, Webb A, Ruble CL, Munsie LM, Nisenbaum LK, Kleinman JE, Lipska BK, Sadee W.

Biol Psychiatry. 2013 Mar 15;73(6):546-54. doi: 10.1016/j.biopsych.2012.09.028. Epub 2012 Nov 13.


Polymorphism in glutamate cysteine ligase catalytic subunit (GCLC) is associated with sulfamethoxazole-induced hypersensitivity in HIV/AIDS patients.

Wang D, Curtis A, Papp AC, Koletar SL, Para MF.

BMC Med Genomics. 2012 Jul 23;5:32. doi: 10.1186/1755-8794-5-32.


Cholesteryl Ester Transfer Protein (CETP) polymorphisms affect mRNA splicing, HDL levels, and sex-dependent cardiovascular risk.

Papp AC, Pinsonneault JK, Wang D, Newman LC, Gong Y, Johnson JA, Pepine CJ, Kumari M, Hingorani AD, Talmud PJ, Shah S, Humphries SE, Sadee W.

PLoS One. 2012;7(3):e31930. doi: 10.1371/journal.pone.0031930. Epub 2012 Mar 5.


Pharmacogenomics of the RNA world: structural RNA polymorphisms in drug therapy.

Sadee W, Wang D, Papp AC, Pinsonneault JK, Smith RM, Moyer RA, Johnson AD.

Clin Pharmacol Ther. 2011 Mar;89(3):355-65. doi: 10.1038/clpt.2010.314. Epub 2011 Feb 2. Review.


Intronic polymorphisms affecting alternative splicing of human dopamine D2 receptor are associated with cocaine abuse.

Moyer RA, Wang D, Papp AC, Smith RM, Duque L, Mash DC, Sadee W.

Neuropsychopharmacology. 2011 Mar;36(4):753-62. doi: 10.1038/npp.2010.208. Epub 2010 Dec 8.

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