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Does adjunctive corticosteroid and aspirin therapy improve the outcome of tuberculous meningitis?

Misra UK, Kalita J, Sagar B, Bhoi SK.

Neurol India. 2018 Nov-Dec;66(6):1672-1677. doi: 10.4103/0028-3886.246278.


Current research towards optimizing dosing of first-line antituberculosis treatment.

McIlleron H, Chirehwa MT.

Expert Rev Anti Infect Ther. 2018 Dec 1. doi: 10.1080/14787210.2019.1555031. [Epub ahead of print]


Treatment outcomes for isoniazid-monoresistant tuberculosis in Peru, 2012-2014.

Cornejo Garcia JG, Alarcón Guizado VA, Mendoza Ticona A, Alarcon E, Heldal E, Moore DAJ.

PLoS One. 2018 Dec 4;13(12):e0206658. doi: 10.1371/journal.pone.0206658. eCollection 2018.


Transformation Morphisms and Time-to-Extinction Analysis That Map Therapy Duration From Preclinical Models to Patients With Tuberculosis: Translating From Apples to Oranges.

Magombedze G, Pasipanodya JG, Srivastava S, Deshpande D, Visser ME, Chigutsa E, McIlleron H, Gumbo T.

Clin Infect Dis. 2018 Nov 28;67(suppl_3):S349-S358. doi: 10.1093/cid/ciy623.


Artificial intelligence-derived 3-Way Concentration-dependent Antagonism of Gatifloxacin, Pyrazinamide, and Rifampicin During Treatment of Pulmonary Tuberculosis.

Pasipanodya JG, Smythe W, Merle CS, Olliaro PL, Deshpande D, Magombedze G, McIlleron H, Gumbo T.

Clin Infect Dis. 2018 Nov 28;67(suppl_3):S284-S292. doi: 10.1093/cid/ciy610.


Ethionamide Pharmacokinetics/Pharmacodynamics-derived Dose, the Role of MICs in Clinical Outcome, and the Resistance Arrow of Time in Multidrug-resistant Tuberculosis.

Deshpande D, Pasipanodya JG, Mpagama SG, Srivastava S, Bendet P, Koeuth T, Lee PS, Heysell SK, Gumbo T.

Clin Infect Dis. 2018 Nov 28;67(suppl_3):S317-S326. doi: 10.1093/cid/ciy609.


Prevalence and Clinical Features of Drug Reactions With Eosinophilia and Systemic Symptoms Syndrome Caused by Antituberculosis Drugs: A Retrospective Cohort Study.

Jung HY, Park S, Shin B, Lee JH, Lee SJ, Lee MK, Lee WY, Yong SJ, Kim SH.

Allergy Asthma Immunol Res. 2019 Jan;11(1):90-103. doi: 10.4168/aair.2019.11.1.90.


Substitution of ethambutol with linezolid during the intensive phase of treatment of pulmonary tuberculosis: a prospective, multicentre, randomised, open-label, phase 2 trial.

Lee JK, Lee JY, Kim DK, Yoon HI, Jeong I, Heo EY, Park YS, Jo YS, Lee JH, Park SS, Park JS, Kim J, Lee SM, Joh JS, Lee CH, Lee J, Choi SM, Park JH, Lee SH, Cho YJ, Lee YJ, Kim SJ, Kwak N, Hwang YR, Kim H, Ki J, Lim JN, Choi HS, Lee M, Song T, Kim HS, Han J, Ahn H, Hahn S, Yim JJ.

Lancet Infect Dis. 2018 Nov 23. pii: S1473-3099(18)30480-8. doi: 10.1016/S1473-3099(18)30480-8. [Epub ahead of print]


Small-Cell Lung Cancer Comorbid with Pulmonary Mycobacterium avium Infection: A Case Report.

Yamasaki M, Funaishi K, Saito N, Sakamoto KI, Ishiyama S, Kawamoto K, Matsumoto Y, Matsumoto N, Taniwaki M, Ohashi N, Hattori N.

Chemotherapy. 2018 Nov 22;63(5):257-261. doi: 10.1159/000494504. [Epub ahead of print]


Differentially Detectable Mycobacterium tuberculosis Cells in Sputum from Treatment-Naive Subjects in Haiti and Their Proportionate Increase after Initiation of Treatment.

McAulay K, Saito K, Warrier T, Walsh KF, Mathurin LD, Royal-Mardi G, Lee MH, Ocheretina O, Pape JW, Fitzgerald DW, Nathan CF.

MBio. 2018 Nov 20;9(6). pii: e02192-18. doi: 10.1128/mBio.02192-18.


Ethambutol targets the glutamate racemase of Mycobacterium tuberculosis-an enzyme involved in peptidoglycan biosynthesis.

Pawar A, Jha P, Konwar C, Chaudhry U, Chopra M, Saluja D.

Appl Microbiol Biotechnol. 2018 Nov 19. doi: 10.1007/s00253-018-9518-z. [Epub ahead of print]


A diagnostic algorithm to investigate pyrazinamide and ethambutol resistance in rifampicin resistant Mycobacterium tuberculosis isolates in a low incidence setting.

Andres S, Gröschel MI, Hillemann D, Merker M, Niemann S, Kranzer K.

Antimicrob Agents Chemother. 2018 Nov 19. pii: AAC.01798-18. doi: 10.1128/AAC.01798-18. [Epub ahead of print]


A Challenging Diagnosis of Ascites: A Case Report of Peritoneal Tuberculosis.

Ruiz J, Ganji M, Canha C, Isache C.

Case Rep Infect Dis. 2018 Oct 23;2018:8136476. doi: 10.1155/2018/8136476. eCollection 2018.


[Measurement of rifampicin concentrations in tuberculous pleural effusion before and after combination treatment with oral and local rifampicin].

Liu QX, Guo DT, Chen L, Ou SP, Huang L, Yan H, Zheng XC, Weng CX, Zhang JY.

Zhonghua Jie He He Hu Xi Za Zhi. 2018 Nov 12;41(11):853-856. doi: 10.3760/cma.j.issn.1001-0939.2018.11.005. Chinese.


A new colorimetric method for rapid detection of ethambutol and streptomycin resistance in Mycobacterium tuberculosis: crystal violet decolorization assay (CVDA).

Coban AY, Akbal AU, Ceyhan I, Uzun M, Sertel Selale D, Aslan G, Delialioglu N, Ozyurt M, Bektore B, Bicmen C, Aslanturk A, Ucarman N, Albay A, Sig AK, Ozkutuk N, Surucuoglu S.

Antonie Van Leeuwenhoek. 2018 Nov 11. doi: 10.1007/s10482-018-1198-2. [Epub ahead of print]


Groups of coevolving positions provide drug resistance to Mycobacterium tuberculosis: a study using targets of first-line antituberculosis drugs.

Vats S, Shanker A.

Int J Antimicrob Agents. 2018 Nov 8. pii: S0924-8579(18)30325-X. doi: 10.1016/j.ijantimicag.2018.10.027. [Epub ahead of print]


The use of optical coherence tomography for the detection of ocular toxicity by ethambutol.

Pavan Taffner BM, Mattos FB, Cunha MCD, Saraiva FP.

PLoS One. 2018 Nov 8;13(11):e0204655. doi: 10.1371/journal.pone.0204655. eCollection 2018.


A Systematic Review on the Effect of HIV Infection on the Pharmacokinetics of First-Line Tuberculosis Drugs.

Daskapan A, Idrus LR, Postma MJ, Wilffert B, Kosterink JGW, Stienstra Y, Touw DJ, Andersen AB, Bekker A, Denti P, Hemanth Kumar AK, Jeremiah K, Kwara A, McIlleron H, Meintjes G, van Oosterhout JJ, Ramachandran G, Rockwood N, Wilkinson RJ, van der Werf TS, Alffenaar JC.

Clin Pharmacokinet. 2018 Nov 8. doi: 10.1007/s40262-018-0716-8. [Epub ahead of print] Review.


Management of De Novo Mycobacterial Infection After Lung Transplantation Without Rifampicin: Case Series of a Single Institution.

Suzuki H, Matsuda Y, Noda M, Oishi H, Watanabe T, Sado T, Yamada M, Tamada T, Okada Y.

Transplant Proc. 2018 Nov;50(9):2764-2767. doi: 10.1016/j.transproceed.2018.03.058. Epub 2018 Mar 15.


Pharmacokinetics of First-Line Drugs Among Children With Tuberculosis in Rural Tanzania.

Justine M, Yeconia A, Nicodemu I, Augustino D, Gratz J, Mduma E, Heysell SK, Kivuyo S, Mfinanga S, Peloquin CA, Zagurski T, Kibiki GS, Mmbaga B, Houpt ER, Thomas TA.

J Pediatric Infect Dis Soc. 2018 Nov 5. doi: 10.1093/jpids/piy106. [Epub ahead of print]


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