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Atypical dopamine transporter inhibitors R-modafinil and JHW 007 differentially affect D2 autoreceptor neurotransmission and the firing rate of midbrain dopamine neurons.

Avelar AJ, Cao J, Newman AH, Beckstead MJ.

Neuropharmacology. 2017 Sep 1;123:410-419. doi: 10.1016/j.neuropharm.2017.06.016. Epub 2017 Jun 15.


The Transcriptome of Type I Murine Astrocytes under Interferon-Gamma Exposure and Remyelination Stimulus.

Kudriaeva A, Galatenko VV, Maltseva DV, Khaustova NA, Kuzina E, Tonevitsky AG, Gabibov A, Belogurov A.

Molecules. 2017 May 15;22(5). pii: E808. doi: 10.3390/molecules22050808.


σ Receptor Effects of N-Substituted Benztropine Analogs: Implications for Antagonism of Cocaine Self-Administration.

Hiranita T, Hong WC, Kopajtic T, Katz JL.

J Pharmacol Exp Ther. 2017 Jul;362(1):2-13. doi: 10.1124/jpet.117.241109. Epub 2017 Apr 25.


The Isomeric Preference of an Atypical Dopamine Transporter Inhibitor Contributes to Its Selection of the Transporter Conformation.

Abramyan AM, Stolzenberg S, Li Z, Loland CJ, Noé F, Shi L.

ACS Chem Neurosci. 2017 Aug 16;8(8):1735-1746. doi: 10.1021/acschemneuro.7b00094. Epub 2017 May 4.


Analysis of spatiotemporal pattern and quantification of gastrointestinal slow waves caused by anticholinergic drugs.

Wong KKL, Tang LCY, Zhou J, Ho V.

Organogenesis. 2017 Apr 3;13(2):39-62. doi: 10.1080/15476278.2017.1295904. Epub 2017 Feb 23.


Identification of novel inhibitors of the amino acid transporter B0 AT1 (SLC6A19), a potential target to induce protein restriction and to treat type 2 diabetes.

Cheng Q, Shah N, Bröer A, Fairweather S, Jiang Y, Schmoll D, Corry B, Bröer S.

Br J Pharmacol. 2017 Mar;174(6):468-482. doi: 10.1111/bph.13711. Epub 2017 Feb 14.


Further delineation between typical and atypical dopamine uptake inhibitors: effects on food-maintained behavior and food consumption.

Slezak JM, Desai RI, Katz JL.

Behav Pharmacol. 2017 Feb;28(1):74-82. doi: 10.1097/FBP.0000000000000278.


New use of an old drug: inhibition of breast cancer stem cells by benztropine mesylate.

Cui J, Hollmén M, Li L, Chen Y, Proulx ST, Reker D, Schneider G, Detmar M.

Oncotarget. 2017 Jan 3;8(1):1007-1022. doi: 10.18632/oncotarget.13537.


mRNA expression profile of mouse oligodendrocytes in inflammatory conditions.

Kudriaeva AA, Khaustova NA, Maltseva DV, Kuzina ES, Glagoleva IS, Surina EA, Knorre VD, Belogurov AA Jr, Tonevitsky AG, Gabibov AG.

Dokl Biochem Biophys. 2016 Jul;469(1):264-8. doi: 10.1134/S1607672916040086. Epub 2016 Sep 7.


α-Synuclein-induced myelination deficit defines a novel interventional target for multiple system atrophy.

Ettle B, Kerman BE, Valera E, Gillmann C, Schlachetzki JC, Reiprich S, Büttner C, Ekici AB, Reis A, Wegner M, Bäuerle T, Riemenschneider MJ, Masliah E, Gage FH, Winkler J.

Acta Neuropathol. 2016 Jul;132(1):59-75. doi: 10.1007/s00401-016-1572-y. Epub 2016 Apr 8.


Prolonged Antimuscarinic Delirium in a Child Due to Benztropine Exposure Treated With Multiple Doses of Physostigmine.

Thornton SL, Farnaes L, Minns A.

Pediatr Emerg Care. 2016 Apr;32(4):243-5. doi: 10.1097/PEC.0000000000000503.


Inhibition of Ebola and Marburg Virus Entry by G Protein-Coupled Receptor Antagonists.

Cheng H, Lear-Rooney CM, Johansen L, Varhegyi E, Chen ZW, Olinger GG, Rong L.

J Virol. 2015 Oct;89(19):9932-8. doi: 10.1128/JVI.01337-15. Epub 2015 Jul 22.


Persistence of racial disparities in prescription of first-generation antipsychotics in the USA.

Cook TB, Reeves GM, Teufel J, Postolache TT.

Pharmacoepidemiol Drug Saf. 2015 Nov;24(11):1197-206. doi: 10.1002/pds.3819. Epub 2015 Jul 1.


Behavioral, biological, and chemical perspectives on atypical agents targeting the dopamine transporter.

Reith ME, Blough BE, Hong WC, Jones KT, Schmitt KC, Baumann MH, Partilla JS, Rothman RB, Katz JL.

Drug Alcohol Depend. 2015 Feb 1;147:1-19. doi: 10.1016/j.drugalcdep.2014.12.005. Epub 2014 Dec 18. Review.


Acute benztropine intoxication and fatality.

McIntyre IM, Mallett P, Burton CG, Morhaime J.

J Forensic Sci. 2014 Nov;59(6):1675-8. doi: 10.1111/1556-4029.12489. Epub 2014 Apr 3.


Modulation of methamphetamine's locomotor stimulation and self-administration by JHW 007, an atypical dopamine reuptake blocker.

Ferragud A, Velázquez-Sánchez C, Canales JJ.

Eur J Pharmacol. 2014 May 15;731:73-9. doi: 10.1016/j.ejphar.2014.03.015. Epub 2014 Mar 25.


Pharmacological characterization of a dopamine transporter ligand that functions as a cocaine antagonist.

Desai RI, Grandy DK, Lupica CR, Katz JL.

J Pharmacol Exp Ther. 2014 Jan;348(1):106-15. doi: 10.1124/jpet.113.208538. Epub 2013 Nov 5.


Preclinical efficacy of N-substituted benztropine analogs as antagonists of methamphetamine self-administration in rats.

Hiranita T, Kohut SJ, Soto PL, Tanda G, Kopajtic TA, Katz JL.

J Pharmacol Exp Ther. 2014 Jan;348(1):174-91. doi: 10.1124/jpet.113.208264. Epub 2013 Nov 5.


A regenerative approach to the treatment of multiple sclerosis.

Deshmukh VA, Tardif V, Lyssiotis CA, Green CC, Kerman B, Kim HJ, Padmanabhan K, Swoboda JG, Ahmad I, Kondo T, Gage FH, Theofilopoulos AN, Lawson BR, Schultz PG, Lairson LL.

Nature. 2013 Oct 17;502(7471):327-332. doi: 10.1038/nature12647. Epub 2013 Oct 9.


Optimal control of nausea and vomiting with a three-drug antiemetic regimen with aprepitant in metastatic pancreatic cancer patients treated with first-line modified FOLFIRINOX.

Silvestris N, Brunetti AE, Russano M, Nardulli P.

Support Care Cancer. 2013 Nov;21(11):2955-6. doi: 10.1007/s00520-013-1944-y. Epub 2013 Aug 23. No abstract available.


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