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Items: 1 to 20 of 607

1.

A new genomic blueprint of the human gut microbiota.

Almeida A, Mitchell AL, Boland M, Forster SC, Gloor GB, Tarkowska A, Lawley TD, Finn RD.

Nature. 2019 Feb 11. doi: 10.1038/s41586-019-0965-1. [Epub ahead of print]

PMID:
30745586
2.

Excessive Cell Growth Causes Cytoplasm Dilution And Contributes to Senescence.

Neurohr GE, Terry RL, Lengefeld J, Bonney M, Brittingham GP, Moretto F, Miettinen TP, Vaites LP, Soares LM, Paulo JA, Harper JW, Buratowski S, Manalis S, van Werven FJ, Holt LJ, Amon A.

Cell. 2019 Jan 29. pii: S0092-8674(19)30051-0. doi: 10.1016/j.cell.2019.01.018. [Epub ahead of print]

3.

Mitophagy inhibits amyloid-β and tau pathology and reverses cognitive deficits in models of Alzheimer's disease.

Fang EF, Hou Y, Palikaras K, Adriaanse BA, Kerr JS, Yang B, Lautrup S, Hasan-Olive MM, Caponio D, Dan X, Rocktäschel P, Croteau DL, Akbari M, Greig NH, Fladby T, Nilsen H, Cader MZ, Mattson MP, Tavernarakis N, Bohr VA.

Nat Neurosci. 2019 Feb 11. doi: 10.1038/s41593-018-0332-9. [Epub ahead of print]

PMID:
30742114
4.

Diabetes relief in mice by glucose-sensing insulin-secreting human α-cells.

Furuyama K, Chera S, van Gurp L, Oropeza D, Ghila L, Damond N, Vethe H, Paulo JA, Joosten AM, Berney T, Bosco D, Dorrell C, Grompe M, Ræder H, Roep BO, Thorel F, Herrera PL.

Nature. 2019 Feb 13. doi: 10.1038/s41586-019-0942-8. [Epub ahead of print]

PMID:
30760930
5.

The Landscape of Circular RNA in Cancer.

Vo JN, Cieslik M, Zhang Y, Shukla S, Xiao L, Zhang Y, Wu YM, Dhanasekaran SM, Engelke CG, Cao X, Robinson DR, Nesvizhskii AI, Chinnaiyan AM.

Cell. 2019 Feb 7;176(4):869-881.e13. doi: 10.1016/j.cell.2018.12.021.

PMID:
30735636
6.

Dietary interventions for induction and maintenance of remission in inflammatory bowel disease.

Limketkai BN, Iheozor-Ejiofor Z, Gjuladin-Hellon T, Parian A, Matarese LE, Bracewell K, MacDonald JK, Gordon M, Mullin GE.

Cochrane Database Syst Rev. 2019 Feb 8;2:CD012839. doi: 10.1002/14651858.CD012839.pub2. [Epub ahead of print] Review.

PMID:
30736095
7.

Melatonin protects mice against stress-induced inflammation through enhancement of M2 macrophage polarization.

Yi WJ, Kim TS.

Int Immunopharmacol. 2017 Jul;48:146-158. doi: 10.1016/j.intimp.2017.05.006. Epub 2017 May 12.

PMID:
28505494
8.

The evolving landscape of biomarkers for checkpoint inhibitor immunotherapy.

Havel JJ, Chowell D, Chan TA.

Nat Rev Cancer. 2019 Feb 12. doi: 10.1038/s41568-019-0116-x. [Epub ahead of print] Review.

PMID:
30755690
9.

Sleep modulates haematopoiesis and protects against atherosclerosis.

McAlpine CS, Kiss MG, Rattik S, He S, Vassalli A, Valet C, Anzai A, Chan CT, Mindur JE, Kahles F, Poller WC, Frodermann V, Fenn AM, Gregory AF, Halle L, Iwamoto Y, Hoyer FF, Binder CJ, Libby P, Tafti M, Scammell TE, Nahrendorf M, Swirski FK.

Nature. 2019 Feb 13. doi: 10.1038/s41586-019-0948-2. [Epub ahead of print]

PMID:
30760925
10.

Spatial and temporal heterogeneity of mouse and human microglia at single-cell resolution.

Masuda T, Sankowski R, Staszewski O, Böttcher C, Amann L, Scheiwe C, Nessler S, Kunz P, van Loo G, Coenen VA, Reinacher PC, Michel A, Sure U, Gold R, Priller J, Stadelmann C, Prinz M.

Nature. 2019 Feb 13. doi: 10.1038/s41586-019-0924-x. [Epub ahead of print]

PMID:
30760929
11.

Management of Hypertension in Chronic Kidney Disease.

Pugh D, Gallacher PJ, Dhaun N.

Drugs. 2019 Feb 13. doi: 10.1007/s40265-019-1064-1. [Epub ahead of print]

PMID:
30758803
12.

Therapies Directed Against B-Cells and Downstream Effectors in Generalized Autoimmune Myasthenia Gravis: Current Status.

Beecher G, Putko BN, Wagner AN, Siddiqi ZA.

Drugs. 2019 Feb 14. doi: 10.1007/s40265-019-1065-0. [Epub ahead of print]

PMID:
30762205
13.

Antitumor Responses in the Absence of Toxicity in Solid Tumors by Targeting B7-H3 via Chimeric Antigen Receptor T Cells.

Du H, Hirabayashi K, Ahn S, Kren NP, Montgomery SA, Wang X, Tiruthani K, Mirlekar B, Michaud D, Greene K, Herrera SG, Xu Y, Sun C, Chen Y, Ma X, Ferrone CR, Pylayeva-Gupta Y, Yeh JJ, Liu R, Savoldo B, Ferrone S, Dotti G.

Cancer Cell. 2019 Feb 11;35(2):221-237.e8. doi: 10.1016/j.ccell.2019.01.002.

PMID:
30753824
14.

Altered human oligodendrocyte heterogeneity in multiple sclerosis.

Jäkel S, Agirre E, Falcão AM, van Bruggen D, Lee KW, Knuesel I, Malhotra D, Ffrench-Constant C, Williams A, Castelo-Branco G.

Nature. 2019 Jan 23. doi: 10.1038/s41586-019-0903-2. [Epub ahead of print]

PMID:
30747918
15.

Distinct Immune Cell Populations Define Response to Anti-PD-1 Monotherapy and Anti-PD-1/Anti-CTLA-4 Combined Therapy.

Gide TN, Quek C, Menzies AM, Tasker AT, Shang P, Holst J, Madore J, Lim SY, Velickovic R, Wongchenko M, Yan Y, Lo S, Carlino MS, Guminski A, Saw RPM, Pang A, McGuire HM, Palendira U, Thompson JF, Rizos H, Silva IPD, Batten M, Scolyer RA, Long GV, Wilmott JS.

Cancer Cell. 2019 Feb 11;35(2):238-255.e6. doi: 10.1016/j.ccell.2019.01.003.

PMID:
30753825
16.

The Effects of Probiotics on Symptoms of Depression: Protocol for a Double-Blind Randomized Placebo-Controlled Trial.

Wallace CJK, Foster JA, Soares CN, Milev RV.

Neuropsychobiology. 2019 Feb 13:1-9. doi: 10.1159/000496406. [Epub ahead of print]

PMID:
30759442
17.

New Approaches for Delirium: A Case for Robotic Pets.

Schulman-Marcus J, Mookherjee S, Rice L, Lyubarova R.

Am J Med. 2019 Feb 7. pii: S0002-9343(19)30123-8. doi: 10.1016/j.amjmed.2018.12.039. [Epub ahead of print] No abstract available.

PMID:
30738728
18.

Engineered CRISPR-Cas12a variants with increased activities and improved targeting ranges for gene, epigenetic and base editing.

Kleinstiver BP, Sousa AA, Walton RT, Tak YE, Hsu JY, Clement K, Welch MM, Horng JE, Malagon-Lopez J, Scarfò I, Maus MV, Pinello L, Aryee MJ, Joung JK.

Nat Biotechnol. 2019 Feb 11. doi: 10.1038/s41587-018-0011-0. [Epub ahead of print]

PMID:
30742127
19.

Landscape of B cell immunity and related immune evasion in human cancers.

Hu X, Zhang J, Wang J, Fu J, Li T, Zheng X, Wang B, Gu S, Jiang P, Fan J, Ying X, Zhang J, Carroll MC, Wucherpfennig KW, Hacohen N, Zhang F, Zhang P, Liu JS, Li B, Liu XS.

Nat Genet. 2019 Feb 11. doi: 10.1038/s41588-018-0339-x. [Epub ahead of print]

PMID:
30742113
20.

Neoadjuvant anti-PD-1 immunotherapy promotes a survival benefit with intratumoral and systemic immune responses in recurrent glioblastoma.

Cloughesy TF, Mochizuki AY, Orpilla JR, Hugo W, Lee AH, Davidson TB, Wang AC, Ellingson BM, Rytlewski JA, Sanders CM, Kawaguchi ES, Du L, Li G, Yong WH, Gaffey SC, Cohen AL, Mellinghoff IK, Lee EQ, Reardon DA, O'Brien BJ, Butowski NA, Nghiemphu PL, Clarke JL, Arrillaga-Romany IC, Colman H, Kaley TJ, de Groot JF, Liau LM, Wen PY, Prins RM.

Nat Med. 2019 Feb 11. doi: 10.1038/s41591-018-0337-7. [Epub ahead of print]

PMID:
30742122

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