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Items: 1 to 20 of 21

1.

Histone Acetyltransferase p300 Induces De Novo Super-Enhancers to Drive Cellular Senescence.

Sen P, Lan Y, Li CY, Sidoli S, Donahue G, Dou Z, Frederick B, Chen Q, Luense LJ, Garcia BA, Dang W, Johnson FB, Adams PD, Schultz DC, Berger SL.

Mol Cell. 2019 Feb 21;73(4):684-698.e8. doi: 10.1016/j.molcel.2019.01.021. Epub 2019 Feb 14.

PMID:
30773298
2.

Senescence Elicits Stemness: A Surprising Mechanism for Cancer Relapse.

Dou Z, Berger SL.

Cell Metab. 2018 Apr 3;27(4):710-711. doi: 10.1016/j.cmet.2018.03.009.

3.

Combinatorial genetics in liver repopulation and carcinogenesis with a in vivo CRISPR activation platform.

Wangensteen KJ, Wang YJ, Dou Z, Wang AW, Mosleh-Shirazi E, Horlbeck MA, Gilbert LA, Weissman JS, Berger SL, Kaestner KH.

Hepatology. 2018 Aug;68(2):663-676. doi: 10.1002/hep.29626. Epub 2018 May 14.

4.

Cytoplasmic chromatin triggers inflammation in senescence and cancer.

Dou Z, Ghosh K, Vizioli MG, Zhu J, Sen P, Wangensteen KJ, Simithy J, Lan Y, Lin Y, Zhou Z, Capell BC, Xu C, Xu M, Kieckhaefer JE, Jiang T, Shoshkes-Carmel M, Tanim KMAA, Barber GN, Seykora JT, Millar SE, Kaestner KH, Garcia BA, Adams PD, Berger SL.

Nature. 2017 Oct 19;550(7676):402-406. doi: 10.1038/nature24050. Epub 2017 Oct 4.

5.

Vps34 regulates Rab7 and late endocytic trafficking through recruitment of the GTPase-activating protein Armus.

Jaber N, Mohd-Naim N, Wang Z, DeLeon JL, Kim S, Zhong H, Sheshadri N, Dou Z, Edinger AL, Du G, Braga VM, Zong WX.

J Cell Sci. 2016 Dec 1;129(23):4424-4435. Epub 2016 Oct 28.

6.

Lysine methylation represses p53 activity in teratocarcinoma cancer cells.

Zhu J, Dou Z, Sammons MA, Levine AJ, Berger SL.

Proc Natl Acad Sci U S A. 2016 Aug 30;113(35):9822-7. doi: 10.1073/pnas.1610387113. Epub 2016 Aug 17.

7.

TRIM21 Ubiquitylates SQSTM1/p62 and Suppresses Protein Sequestration to Regulate Redox Homeostasis.

Pan JA, Sun Y, Jiang YP, Bott AJ, Jaber N, Dou Z, Yang B, Chen JS, Catanzaro JM, Du C, Ding WX, Diaz-Meco MT, Moscat J, Ozato K, Lin RZ, Zong WX.

Mol Cell. 2016 Apr 7;62(1):149-51. doi: 10.1016/j.molcel.2016.03.015. No abstract available.

8.

TRIM21 Ubiquitylates SQSTM1/p62 and Suppresses Protein Sequestration to Regulate Redox Homeostasis.

Pan JA, Sun Y, Jiang YP, Bott AJ, Jaber N, Dou Z, Yang B, Chen JS, Catanzaro JM, Du C, Ding WX, Diaz-Meco MT, Moscat J, Ozato K, Lin RZ, Zong WX.

Mol Cell. 2016 Mar 3;61(5):720-733. doi: 10.1016/j.molcel.2016.02.007. Erratum in: Mol Cell. 2016 Apr 7;62(1):149-51.

9.

MLL1 is essential for the senescence-associated secretory phenotype.

Capell BC, Drake AM, Zhu J, Shah PP, Dou Z, Dorsey J, Simola DF, Donahue G, Sammons M, Rai TS, Natale C, Ridky TW, Adams PD, Berger SL.

Genes Dev. 2016 Feb 1;30(3):321-36. doi: 10.1101/gad.271882.115.

10.

Mammalian autophagy degrades nuclear constituents in response to tumorigenic stress.

Dou Z, Ivanov A, Adams PD, Berger SL.

Autophagy. 2016 Aug 2;12(8):1416-7. doi: 10.1080/15548627.2015.1127465. Epub 2015 Dec 10.

11.

Autophagy mediates degradation of nuclear lamina.

Dou Z, Xu C, Donahue G, Shimi T, Pan JA, Zhu J, Ivanov A, Capell BC, Drake AM, Shah PP, Catanzaro JM, Ricketts MD, Lamark T, Adam SA, Marmorstein R, Zong WX, Johansen T, Goldman RD, Adams PD, Berger SL.

Nature. 2015 Nov 5;527(7576):105-9. doi: 10.1038/nature15548. Epub 2015 Oct 28.

12.

Gain-of-function p53 mutants co-opt chromatin pathways to drive cancer growth.

Zhu J, Sammons MA, Donahue G, Dou Z, Vedadi M, Getlik M, Barsyte-Lovejoy D, Al-awar R, Katona BW, Shilatifard A, Huang J, Hua X, Arrowsmith CH, Berger SL.

Nature. 2015 Sep 10;525(7568):206-11. doi: 10.1038/nature15251. Epub 2015 Sep 2.

13.

Beclin 1 is required for neuron viability and regulates endosome pathways via the UVRAG-VPS34 complex.

McKnight NC, Zhong Y, Wold MS, Gong S, Phillips GR, Dou Z, Zhao Y, Heintz N, Zong WX, Yue Z.

PLoS Genet. 2014 Oct 2;10(10):e1004626. doi: 10.1371/journal.pgen.1004626. eCollection 2014 Oct.

14.

TRIM14 is a mitochondrial adaptor that facilitates retinoic acid-inducible gene-I-like receptor-mediated innate immune response.

Zhou Z, Jia X, Xue Q, Dou Z, Ma Y, Zhao Z, Jiang Z, He B, Jin Q, Wang J.

Proc Natl Acad Sci U S A. 2014 Jan 14;111(2):E245-54. doi: 10.1073/pnas.1316941111. Epub 2013 Dec 30.

15.

Class IA PI3K p110β subunit promotes autophagy through Rab5 small GTPase in response to growth factor limitation.

Dou Z, Pan JA, Dbouk HA, Ballou LM, DeLeon JL, Fan Y, Chen JS, Liang Z, Li G, Backer JM, Lin RZ, Zong WX.

Mol Cell. 2013 Apr 11;50(1):29-42. doi: 10.1016/j.molcel.2013.01.022. Epub 2013 Feb 21.

16.

Mammalian PIK3C3/VPS34: the key to autophagic processing in liver and heart.

Jaber N, Dou Z, Lin RZ, Zhang J, Zong WX.

Autophagy. 2012 Apr;8(4):707-8. doi: 10.4161/auto.19627. Epub 2012 Apr 1.

17.

Class III PI3K Vps34 plays an essential role in autophagy and in heart and liver function.

Jaber N, Dou Z, Chen JS, Catanzaro J, Jiang YP, Ballou LM, Selinger E, Ouyang X, Lin RZ, Zhang J, Zong WX.

Proc Natl Acad Sci U S A. 2012 Feb 7;109(6):2003-8. doi: 10.1073/pnas.1112848109. Epub 2012 Jan 23.

18.
19.

The beta identity of class I PtdIns3K: A positive role of p110β in autophagy revealed.

Dou Z, Pan JA, Lin RZ, Zong WX.

Autophagy. 2011 Feb;7(2):246-7. Epub 2011 Feb 1.

20.

The class IA phosphatidylinositol 3-kinase p110-beta subunit is a positive regulator of autophagy.

Dou Z, Chattopadhyay M, Pan JA, Guerriero JL, Jiang YP, Ballou LM, Yue Z, Lin RZ, Zong WX.

J Cell Biol. 2010 Nov 15;191(4):827-43. doi: 10.1083/jcb.201006056. Epub 2010 Nov 8.

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