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Items: 1 to 20 of 67


Transcriptional regulation of microalgae for concurrent lipid overproduction and secretion.

Li DW, Balamurugan S, Yang YF, Zheng JW, Huang D, Zou LG, Yang WD, Liu JS, Guan Y, Li HY.

Sci Adv. 2019 Jan 30;5(1):eaau3795. doi: 10.1126/sciadv.aau3795. eCollection 2019 Jan.


Anchor: trans-cell type prediction of transcription factor binding sites.

Li H, Quang D, Guan Y.

Genome Res. 2019 Feb;29(2):281-292. doi: 10.1101/gr.237156.118. Epub 2018 Dec 19.


BaiHui: Cross-species Brain-specific Network Built with Hundreds of Hand-curated Datasets.

Li HD, Bai T, Sandford E, Burmeister M, Guan Y.

Bioinformatics. 2018 Dec 5. doi: 10.1093/bioinformatics/bty1001. [Epub ahead of print]


TAIJI: Approaching Experimental Replicates-Level Accuracy for Drug Synergy Prediction.

Li H, Hu S, Neamati N, Guan Y.

Bioinformatics. 2018 Nov 21. doi: 10.1093/bioinformatics/bty955. [Epub ahead of print]


Model-Based and Model-Free Techniques for Amyotrophic Lateral Sclerosis Diagnostic Prediction and Patient Clustering.

Tang M, Gao C, Goutman SA, Kalinin A, Mukherjee B, Guan Y, Dinov ID.

Neuroinformatics. 2018 Nov 20. doi: 10.1007/s12021-018-9406-9. [Epub ahead of print]


High-Throughput Single-Cell Sequencing of both TCR-β Alleles.

Hosoya T, Li H, Ku CJ, Wu Q, Guan Y, Engel JD.

J Immunol. 2018 Dec 1;201(11):3465-3470. doi: 10.4049/jimmunol.1800774. Epub 2018 Oct 31.


Chromosome 17 Missing Proteins: Recent Progress and Future Directions as Part of the neXt-MP50 Challenge.

Siddiqui O, Zhang H, Guan Y, Omenn GS.

J Proteome Res. 2018 Oct 23. doi: 10.1021/acs.jproteome.8b00442. [Epub ahead of print]


Clinical applications of machine learning in cardiovascular disease and its relevance to cardiac imaging.

Al'Aref SJ, Anchouche K, Singh G, Slomka PJ, Kolli KK, Kumar A, Pandey M, Maliakal G, van Rosendael AR, Beecy AN, Berman DS, Leipsic J, Nieman K, Andreini D, Pontone G, Schoepf UJ, Shaw LJ, Chang HJ, Narula J, Bax JJ, Guan Y, Min JK.

Eur Heart J. 2018 Jul 27. doi: 10.1093/eurheartj/ehy404. [Epub ahead of print]


Network Propagation Predicts Drug Synergy in Cancers.

Li H, Li T, Quang D, Guan Y.

Cancer Res. 2018 Sep 15;78(18):5446-5457. doi: 10.1158/0008-5472.CAN-18-0740. Epub 2018 Jul 27.


A similarity-based approach to leverage multi-cohort medical data on the diagnosis and prognosis of Alzheimer's disease.

Zhang H, Zhu F, Dodge HH, Higgins GA, Omenn GS, Guan Y; Alzheimer's Disease Neuroimaging Initiative.

Gigascience. 2018 Jul 1;7(7). doi: 10.1093/gigascience/giy085.


Prioritizing predictive biomarkers for gene essentiality in cancer cells with mRNA expression data and DNA copy number profile.

Guan Y, Li T, Zhang H, Zhu F, Omenn GS.

Bioinformatics. 2018 Dec 1;34(23):3975-3982. doi: 10.1093/bioinformatics/bty467.


YAMDA: thousandfold speedup of EM-based motif discovery using deep learning libraries and GPU.

Quang D, Guan Y, Parker SCJ.

Bioinformatics. 2018 Oct 15;34(20):3578-3580. doi: 10.1093/bioinformatics/bty396.


DNAp: A Pipeline for DNA-seq Data Analysis.

Causey JL, Ashby C, Walker K, Wang ZP, Yang M, Guan Y, Moore JH, Huang X.

Sci Rep. 2018 May 1;8(1):6793. doi: 10.1038/s41598-018-25022-6.


Brain-specific functional relationship networks inform autism spectrum disorder gene prediction.

Duda M, Zhang H, Li HD, Wall DP, Burmeister M, Guan Y.

Transl Psychiatry. 2018 Mar 6;8(1):56. doi: 10.1038/s41398-018-0098-6.


Accurate prediction of personalized olfactory perception from large-scale chemoinformatic features.

Li H, Panwar B, Omenn GS, Guan Y.

Gigascience. 2018 Feb 1;7(2). doi: 10.1093/gigascience/gix127.


Complete hazard ranking to analyze right-censored data: An ALS survival study.

Huang Z, Zhang H, Boss J, Goutman SA, Mukherjee B, Dinov ID, Guan Y; Pooled Resource Open-Access ALS Clinical Trials Consortium.

PLoS Comput Biol. 2017 Dec 18;13(12):e1005887. doi: 10.1371/journal.pcbi.1005887. eCollection 2017 Dec.


A Community Challenge for Inferring Genetic Predictors of Gene Essentialities through Analysis of a Functional Screen of Cancer Cell Lines.

Gönen M, Weir BA, Cowley GS, Vazquez F, Guan Y, Jaiswal A, Karasuyama M, Uzunangelov V, Wang T, Tsherniak A, Howell S, Marbach D, Hoff B, Norman TC, Airola A, Bivol A, Bunte K, Carlin D, Chopra S, Deran A, Ellrott K, Gopalacharyulu P, Graim K, Kaski S, Khan SA, Newton Y, Ng S, Pahikkala T, Paull E, Sokolov A, Tang H, Tang J, Wennerberg K, Xie Y, Zhan X, Zhu F; Broad-DREAM Community, Aittokallio T, Mamitsuka H, Stuart JM, Boehm JS, Root DE, Xiao G, Stolovitzky G, Hahn WC, Margolin AA.

Cell Syst. 2017 Nov 22;5(5):485-497.e3. doi: 10.1016/j.cels.2017.09.004. Epub 2017 Oct 4.


Comparison of spinocerebellar ataxia type 3 mouse models identifies early gain-of-function, cell-autonomous transcriptional changes in oligodendrocytes.

Ramani B, Panwar B, Moore LR, Wang B, Huang R, Guan Y, Paulson HL.

Hum Mol Genet. 2017 Sep 1;26(17):3362-3374. doi: 10.1093/hmg/ddx224.


Conversion Discriminative Analysis on Mild Cognitive Impairment Using Multiple Cortical Features from MR Images.

Guo S, Lai C, Wu C, Cen G; Alzheimer's Disease Neuroimaging Initiative.

Front Aging Neurosci. 2017 May 18;9:146. doi: 10.3389/fnagi.2017.00146. eCollection 2017. Erratum in: Front Aging Neurosci. 2017 Sep 05;9:293.


GATA3 Abundance Is a Critical Determinant of T Cell Receptor β Allelic Exclusion.

Ku CJ, Sekiguchi JM, Panwar B, Guan Y, Takahashi S, Yoh K, Maillard I, Hosoya T, Engel JD.

Mol Cell Biol. 2017 May 31;37(12). pii: e00052-17. doi: 10.1128/MCB.00052-17. Print 2017 Jun 15.

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