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Items: 1 to 20 of 48


Cleavage of osmosensitive transcriptional factor NFAT5 by Coxsackieviral protease 2A promotes viral replication.

Qiu Y, Ye X, Zhang HM, Hanson P, Zhao G, Tong L, Xie R, Yang D.

PLoS Pathog. 2017 Dec 8;13(12):e1006744. doi: 10.1371/journal.ppat.1006744. eCollection 2017 Dec.


Heat shock protein 70 promotes coxsackievirus B3 translation initiation and elongation via Akt-mTORC1 pathway depending on activation of p70S6K and Cdc2.

Wang F, Qiu Y, Zhang HM, Hanson P, Ye X, Zhao G, Xie R, Tong L, Yang D.

Cell Microbiol. 2017 Jul;19(7). doi: 10.1111/cmi.12725. Epub 2017 Feb 1.


Emodin inhibits coxsackievirus B3 replication via multiple signalling cascades leading to suppression of translation.

Zhang HM, Wang F, Qiu Y, Ye X, Hanson P, Shen H, Yang D.

Biochem J. 2016 Feb 15;473(4):473-85. doi: 10.1042/BJ20150419. Epub 2015 Nov 30.


Cleavage of DAP5 by coxsackievirus B3 2A protease facilitates viral replication and enhances apoptosis by altering translation of IRES-containing genes.

Hanson PJ, Ye X, Qiu Y, Zhang HM, Hemida MG, Wang F, Lim T, Gu A, Cho B, Kim H, Fung G, Granville DJ, Yang D.

Cell Death Differ. 2016 May;23(5):828-40. doi: 10.1038/cdd.2015.145. Epub 2015 Nov 20.


Hsp70-1: upregulation via selective phosphorylation of heat shock factor 1 during coxsackieviral infection and promotion of viral replication via the AU-rich element.

Qiu Y, Ye X, Hanson PJ, Zhang HM, Zong J, Cho B, Yang D.

Cell Mol Life Sci. 2016 Mar;73(5):1067-84. doi: 10.1007/s00018-015-2036-6. Epub 2015 Sep 11.


Involvement of Endoplasmic Reticulum Stress-Mediated C/EBP Homologous Protein Activation in Coxsackievirus B3-Induced Acute Viral Myocarditis.

Cai Z, Shen L, Ma H, Yang J, Yang D, Chen H, Wei J, Lu Q, Wang DW, Xiang M, Wang J.

Circ Heart Fail. 2015 Jul;8(4):809-18. doi: 10.1161/CIRCHEARTFAILURE.114.001244. Epub 2015 May 18.


Coxsackievirus B3 replication and pathogenesis.

Garmaroudi FS, Marchant D, Hendry R, Luo H, Yang D, Ye X, Shi J, McManus BM.

Future Microbiol. 2015;10(4):629-53. doi: 10.2217/fmb.15.5. Review.


Coxsackievirus-induced miR-21 disrupts cardiomyocyte interactions via the downregulation of intercalated disk components.

Ye X, Zhang HM, Qiu Y, Hanson PJ, Hemida MG, Wei W, Hoodless PA, Chu F, Yang D.

PLoS Pathog. 2014 Apr 10;10(4):e1004070. doi: 10.1371/journal.ppat.1004070. eCollection 2014 Apr.


Antiviral activity of an isatin derivative via induction of PERK-Nrf2-mediated suppression of cap-independent translation.

Zhang HM, Dai H, Hanson PJ, Li H, Guo H, Ye X, Hemida MG, Wang L, Tong Y, Qiu Y, Liu S, Wang F, Song F, Zhang B, Wang JG, Zhang LX, Yang D.

ACS Chem Biol. 2014 Apr 18;9(4):1015-24. doi: 10.1021/cb400775z. Epub 2014 Feb 18.


P58(IPK) inhibits coxsackievirus-induced apoptosis via the PI3K/Akt pathway requiring activation of ATF6a and subsequent upregulation of mitofusin 2.

Zhang HM, Qiu Y, Ye X, Hemida MG, Hanson P, Yang D.

Cell Microbiol. 2014 Mar;16(3):411-24. doi: 10.1111/cmi.12229. Epub 2013 Nov 6.


MiR-126 promotes coxsackievirus replication by mediating cross-talk of ERK1/2 and Wnt/β-catenin signal pathways.

Ye X, Hemida MG, Qiu Y, Hanson PJ, Zhang HM, Yang D.

Cell Mol Life Sci. 2013 Dec;70(23):4631-44. doi: 10.1007/s00018-013-1411-4. Epub 2013 Jun 30.


An ERK-p38 subnetwork coordinates host cell apoptosis and necrosis during coxsackievirus B3 infection.

Jensen KJ, Garmaroudi FS, Zhang J, Lin J, Boroomand S, Zhang M, Luo Z, Yang D, Luo H, McManus BM, Janes KA.

Cell Host Microbe. 2013 Jan 16;13(1):67-76. doi: 10.1016/j.chom.2012.11.009. Epub 2013 Jan 16.


MicroRNA-203 enhances coxsackievirus B3 replication through targeting zinc finger protein-148.

Hemida MG, Ye X, Zhang HM, Hanson PJ, Liu Z, McManus BM, Yang D.

Cell Mol Life Sci. 2013 Jan;70(2):277-91. doi: 10.1007/s00018-012-1104-4. Epub 2012 Jul 29.


The immunity-related GTPase Irgm3 relieves endoplasmic reticulum stress response during coxsackievirus B3 infection via a PI3K/Akt dependent pathway.

Liu Z, Zhang HM, Yuan J, Ye X, Taylor GA, Yang D.

Cell Microbiol. 2012 Jan;14(1):133-46. doi: 10.1111/j.1462-5822.2011.01708.x. Epub 2011 Nov 10.


Small interfering RNA against the 2C genomic region of coxsackievirus B3 exerts potential antiviral effects in permissive HeLa cells.

Luan Y, Dai HL, Yang D, Zhu L, Gao TL, Shao HJ, Peng X, Jin ZF.

Virus Res. 2012 Jan;163(1):183-9. doi: 10.1016/j.virusres.2011.09.016. Epub 2011 Sep 16.


Targeted delivery of mutant tolerant anti-coxsackievirus artificial microRNAs using folate conjugated bacteriophage Phi29 pRNA.

Ye X, Liu Z, Hemida MG, Yang D.

PLoS One. 2011;6(6):e21215. doi: 10.1371/journal.pone.0021215. Epub 2011 Jun 15.


Coxsackievirus B3 infection activates the unfolded protein response and induces apoptosis through downregulation of p58IPK and activation of CHOP and SREBP1.

Zhang HM, Ye X, Su Y, Yuan J, Liu Z, Stein DA, Yang D.

J Virol. 2010 Sep;84(17):8446-59. doi: 10.1128/JVI.01416-09. Epub 2010 Jun 16.


Targeted delivery of anti-coxsackievirus siRNAs using ligand-conjugated packaging RNAs.

Zhang HM, Su Y, Guo S, Yuan J, Lim T, Liu J, Guo P, Yang D.

Antiviral Res. 2009 Sep;83(3):307-16. doi: 10.1016/j.antiviral.2009.07.005. Epub 2009 Jul 16.


CXCL10 inhibits viral replication through recruitment of natural killer cells in coxsackievirus B3-induced myocarditis.

Yuan J, Liu Z, Lim T, Zhang H, He J, Walker E, Shier C, Wang Y, Su Y, Sall A, McManus B, Yang D.

Circ Res. 2009 Mar 13;104(5):628-38. doi: 10.1161/CIRCRESAHA.108.192179. Epub 2009 Jan 22.


Focal adhesion kinase mediates the interferon-gamma-inducible GTPase-induced phosphatidylinositol 3-kinase/Akt survival pathway and further initiates a positive feedback loop of NF-kappaB activation.

Liu Z, Zhang HM, Yuan J, Lim T, Sall A, Taylor GA, Yang D.

Cell Microbiol. 2008 Sep;10(9):1787-800. doi: 10.1111/j.1462-5822.2008.01165.x. Epub 2008 Apr 28.

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