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Items: 14


Profound Tissue Specificity in Proliferation Control Underlies Cancer Drivers and Aneuploidy Patterns.

Sack LM, Davoli T, Li MZ, Li Y, Xu Q, Naxerova K, Wooten EC, Bernardi RJ, Martin TD, Chen T, Leng Y, Liang AC, Scorsone KA, Westbrook TF, Wong KK, Elledge SJ.

Cell. 2018 Apr 5;173(2):499-514.e23. doi: 10.1016/j.cell.2018.02.037. Epub 2018 Mar 22.


Tumor aneuploidy correlates with markers of immune evasion and with reduced response to immunotherapy.

Davoli T, Uno H, Wooten EC, Elledge SJ.

Science. 2017 Jan 20;355(6322). pii: eaaf8399. doi: 10.1126/science.aaf8399.


Functional genomics reveals that tumors with activating phosphoinositide 3-kinase mutations are dependent on accelerated protein turnover.

Davoli T, Mengwasser KE, Duan J, Chen T, Christensen C, Wooten EC, Anselmo AN, Li MZ, Wong KK, Kahle KT, Elledge SJ.

Genes Dev. 2016 Dec 15;30(24):2684-2695. doi: 10.1101/gad.290122.116.


Notch pathway activation contributes to inhibition of C2C12 myoblast differentiation by ethanol.

Arya MA, Tai AK, Wooten EC, Parkin CD, Kudryavtseva E, Huggins GS.

PLoS One. 2013 Aug 20;8(8):e71632. doi: 10.1371/journal.pone.0071632. eCollection 2013.


Formin homology 2 domain containing 3 variants associated with hypertrophic cardiomyopathy.

Wooten EC, Hebl VB, Wolf MJ, Greytak SR, Orr NM, Draper I, Calvino JE, Kapur NK, Maron MS, Kullo IJ, Ommen SR, Bos JM, Ackerman MJ, Huggins GS.

Circ Cardiovasc Genet. 2013 Feb;6(1):10-8. doi: 10.1161/CIRCGENETICS.112.965277. Epub 2012 Dec 19.


Lack of association of Klotho gene variants with valvular and vascular calcification in Caucasians: a candidate gene study of the Framingham Offspring Cohort.

Tangri N, Alam A, Wooten EC, Huggins GS.

Nephrol Dial Transplant. 2011 Dec;26(12):3998-4002. doi: 10.1093/ndt/gfr188. Epub 2011 May 12.


Mind the dbGAP: the application of data mining to identify biological mechanisms.

Wooten EC, Huggins GS.

Mol Interv. 2011 Apr;11(2):95-102. doi: 10.1124/mi.11.2.6. No abstract available.


Application of gene network analysis techniques identifies AXIN1/PDIA2 and endoglin haplotypes associated with bicuspid aortic valve.

Wooten EC, Iyer LK, Montefusco MC, Hedgepeth AK, Payne DD, Kapur NK, Housman DE, Mendelsohn ME, Huggins GS.

PLoS One. 2010 Jan 21;5(1):e8830. doi: 10.1371/journal.pone.0008830.


Increased FOG-2 in failing myocardium disrupts thyroid hormone-dependent SERCA2 gene transcription.

Rouf R, Greytak S, Wooten EC, Wu J, Boltax J, Picard M, Svensson EC, Dillmann WH, Patten RD, Huggins GS.

Circ Res. 2008 Aug 29;103(5):493-501. doi: 10.1161/CIRCRESAHA.108.181487. Epub 2008 Jul 25.


Patterns of resistance and incomplete response to docetaxel by gene expression profiling in breast cancer patients.

Chang JC, Wooten EC, Tsimelzon A, Hilsenbeck SG, Gutierrez MC, Tham YL, Kalidas M, Elledge R, Mohsin S, Osborne CK, Chamness GC, Allred DC, Lewis MT, Wong H, O'Connell P.

J Clin Oncol. 2005 Feb 20;23(6):1169-77.


Coordinated upregulation of oxidative pathways and downregulation of lipid biosynthesis underlie obesity resistance in perilipin knockout mice: a microarray gene expression profile.

Castro-Chavez F, Yechoor VK, Saha PK, Martinez-Botas J, Wooten EC, Sharma S, O'Connell P, Taegtmeyer H, Chan L.

Diabetes. 2003 Nov;52(11):2666-74.


Gene expression profiling for the prediction of therapeutic response to docetaxel in patients with breast cancer.

Chang JC, Wooten EC, Tsimelzon A, Hilsenbeck SG, Gutierrez MC, Elledge R, Mohsin S, Osborne CK, Chamness GC, Allred DC, O'Connell P.

Lancet. 2003 Aug 2;362(9381):362-9.


A study of loss of heterozygosity at 70 loci in anaplastic astrocytoma and glioblastoma multiforme with implications for tumor evolution.

Wooten EC, Fults D, Duggirala R, Williams K, Kyritsis AP, Bondy ML, Levin VA, O'Connell P.

Neuro Oncol. 1999 Jul;1(3):169-76. doi: 10.1093/neuonc/1.3.169.


An electronic reticle generator for use with CT scanners.

Wooten EC, Friauf WS.

J Comput Assist Tomogr. 1980 Feb;4(1):130-1.


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