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Items: 1 to 20 of 22


Vaccine-induced effector-memory CD8+ T cell responses predict therapeutic efficacy against tumors.

van Duikeren S, Fransen MF, Redeker A, Wieles B, Platenburg G, Krebber WJ, Ossendorp F, Melief CJ, Arens R.

J Immunol. 2012 Oct 1;189(7):3397-403. Epub 2012 Aug 22.


Hypomethylating drugs convert HA-1-negative solid tumors into targets for stem cell-based immunotherapy.

Hambach L, Ling KW, Pool J, Aghai Z, Blokland E, Tanke HJ, Bruijn JA, Halfwerk H, van Boven H, Wieles B, Goulmy E.

Blood. 2009 Mar 19;113(12):2715-22. doi: 10.1182/blood-2008-05-158956. Epub 2008 Dec 18.


The diallelic locus encoding the minor histocompatibility antigen HA-1 is evolutionarily conserved.

Wieles B, Pool J, Wilke M, Weber M, Kolb HJ, Bontrop RE, Goulmy E.

Tissue Antigens. 2006 Jul;68(1):62-5.


Adult and cord blood T cells can acquire HA-1 specificity through HA-1 T-cell receptor gene transfer.

Mommaas B, van Halteren AG, Pool J, van der Veken L, Wieles B, Heemskerk MH, Goulmy E.

Haematologica. 2005 Oct;90(10):1415-21.


Postgenomic approach to identify novel Mycobacterium leprae antigens with potential to improve immunodiagnosis of infection.

Geluk A, Klein MR, Franken KL, van Meijgaarden KE, Wieles B, Pereira KC, Bührer-Sékula S, Klatser PR, Brennan PJ, Spencer JS, Williams DL, Pessolani MC, Sampaio EP, Ottenhoff TH.

Infect Immun. 2005 Sep;73(9):5636-44.


Detection of microchimerism by minor histocompatibility antigen HA-1 allele-specific nested polymerase chain reaction.

Wieles B, Pool J, Derks R, Burlingham WJ, Goulmy E.

Biol Blood Marrow Transplant. 2005 May;11(5):345-8.


Minor histocompatibility antigens--big in tumour therapy.

Spierings E, Wieles B, Goulmy E.

Trends Immunol. 2004 Feb;25(2):56-60. Review.


Immunological crossreactivity of the Mycobacterium leprae CFP-10 with its homologue in Mycobacterium tuberculosis.

Geluk A, van Meijgaarden KE, Franken KL, Wieles B, Arend SM, Faber WR, Naafs B, Ottenhoff TH.

Scand J Immunol. 2004 Jan;59(1):66-70.


Identification and characterization of the ESAT-6 homologue of Mycobacterium leprae and T-cell cross-reactivity with Mycobacterium tuberculosis.

Geluk A, van Meijgaarden KE, Franken KL, Subronto YW, Wieles B, Arend SM, Sampaio EP, de Boer T, Faber WR, Naafs B, Ottenhoff TH.

Infect Immun. 2002 May;70(5):2544-8.


Presence of human T-cell responses to the Mycobacterium leprae 45-kilodalton antigen reflects infection with or exposure to M. leprae.

Macfarlane A, Mondragon-Gonzalez R, Vega-Lopez F, Wieles B, de Pena J, Rodriguez O, Suarez y de la Torre R, de Vries RR, Ottenhoff TH, Dockrell HM.

Clin Diagn Lab Immunol. 2001 May;8(3):604-11.


HLA-class II-associated control of antigen recognition by T cells in leprosy: a prominent role for the 30/31-kDa antigens.

Thole JE, Janson AA, Cornelisse Y, Schreuder GM, Wieles B, Naafs B, de Vries RR, Ottenhoff TH.

J Immunol. 1999 Jun 1;162(11):6912-8.


Increased intracellular survival of Mycobacterium smegmatis containing the Mycobacterium leprae thioredoxin-thioredoxin reductase gene.

Wieles B, Ottenhoff TH, Steenwijk TM, Franken KL, de Vries RR, Langermans JA.

Infect Immun. 1997 Jul;65(7):2537-41.


The emb operon, a gene cluster of Mycobacterium tuberculosis involved in resistance to ethambutol.

Telenti A, Philipp WJ, Sreevatsan S, Bernasconi C, Stockbauer KE, Wieles B, Musser JM, Jacobs WR Jr.

Nat Med. 1997 May;3(5):567-70.


Immunological and functional characterization of Mycobacterium leprae protein antigens: an overview.

Thole JE, Wieles B, Clark-Curtiss JE, Ottenhoff TH, Rinke de Wit TF.

Mol Microbiol. 1995 Dec;18(5):791-800. Review.


Identification and functional characterization of thioredoxin of Mycobacterium tuberculosis.

Wieles B, Nagai S, Wiker HG, Harboe M, Ottenhoff TH.

Infect Immun. 1995 Dec;63(12):4946-8.


Molecular characterization and T-cell-stimulatory capacity of Mycobacterium leprae antigen T5.

Wieles B, Spierings E, van Noort J, Naafs B, Offringa R, Ottenhoff T.

Infect Immun. 1995 Dec;63(12):4682-5.


Purification and functional analysis of the Mycobacterium leprae thioredoxin/thioredoxin reductase hybrid protein.

Wieles B, van Noort J, Drijfhout JW, Offringa R, Holmgren A, Ottenhoff TH.

J Biol Chem. 1995 Oct 27;270(43):25604-6.


Unique gene organization of thioredoxin and thioredoxin reductase in Mycobacterium leprae.

Wieles B, van Soolingen D, Holmgren A, Offringa R, Ottenhoff T, Thole J.

Mol Microbiol. 1995 Jun;16(5):921-9.


Characterization of a Mycobacterium leprae antigen related to the secreted Mycobacterium tuberculosis protein MPT32.

Wieles B, van Agterveld M, Janson A, Clark-Curtiss J, Rinke de Wit T, Harboe M, Thole J.

Infect Immun. 1994 Jan;62(1):252-8.

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