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Items: 1 to 20 of 172

1.

A Hybrid Insulin Epitope Maintains High 2D Affinity for Diabetogenic T Cells in the Periphery.

Liu B, Hood JD, Kolawole EM, Woodruff DM, Vignali DA, Bettini M, Evavold BD.

Diabetes. 2019 Dec 5. pii: db190399. doi: 10.2337/db19-0399. [Epub ahead of print]

PMID:
31806623
2.

Metastatic breast cancers have reduced immune cell recruitment but harbor increased macrophages relative to their matched primary tumors.

Zhu L, Narloch JL, Onkar S, Joy M, Broadwater G, Luedke C, Hall A, Kim R, Pogue-Geile K, Sammons S, Nayyar N, Chukwueke U, Brastianos PK, Anders CK, Soloff AC, Vignali DAA, Tseng GC, Emens LA, Lucas PC, Blackwell KL, Oesterreich S, Lee AV.

J Immunother Cancer. 2019 Oct 18;7(1):265. doi: 10.1186/s40425-019-0755-1.

3.

Inhibitory receptors and ligands beyond PD-1, PD-L1 and CTLA-4: breakthroughs or backups.

Andrews LP, Yano H, Vignali DAA.

Nat Immunol. 2019 Nov;20(11):1425-1434. doi: 10.1038/s41590-019-0512-0. Epub 2019 Oct 14. Review.

PMID:
31611702
4.

Lymphocyte-activation gene 3 (LAG3): The next immune checkpoint receptor.

Ruffo E, Wu RC, Bruno TC, Workman CJ, Vignali DAA.

Semin Immunol. 2019 Apr;42:101305. doi: 10.1016/j.smim.2019.101305. Review.

PMID:
31604537
5.

Pancreatic cancer-associated inflammation drives dynamic regulation of p35 and Ebi3.

Michaud D, Mirlekar B, Bischoff S, Cowley DO, Vignali DAA, Pylayeva-Gupta Y.

Cytokine. 2020 Jan;125:154817. doi: 10.1016/j.cyto.2019.154817. Epub 2019 Aug 28.

PMID:
31472403
6.

Treg Cells Promote the SREBP1-Dependent Metabolic Fitness of Tumor-Promoting Macrophages via Repression of CD8+ T Cell-Derived Interferon-γ.

Liu C, Chikina M, Deshpande R, Menk AV, Wang T, Tabib T, Brunazzi EA, Vignali KM, Sun M, Stolz DB, Lafyatis RA, Chen W, Delgoffe GM, Workman CJ, Wendell SG, Vignali DAA.

Immunity. 2019 Aug 20;51(2):381-397.e6. doi: 10.1016/j.immuni.2019.06.017. Epub 2019 Jul 23.

PMID:
31350177
7.

Intratumoral regulatory T cells: markers, subsets and their impact on anti-tumor immunity.

Yano H, Andrews LP, Workman CJ, Vignali DAA.

Immunology. 2019 Jul;157(3):232-247. doi: 10.1111/imm.13067. Epub 2019 Jun 3. Review.

PMID:
31087644
8.

A Bayesian mixture model for clustering droplet-based single-cell transcriptomic data from population studies.

Sun Z, Chen L, Xin H, Jiang Y, Huang Q, Cillo AR, Tabib T, Kolls JK, Bruno TC, Lafyatis R, Vignali DAA, Chen K, Ding Y, Hu M, Chen W.

Nat Commun. 2019 Apr 9;10(1):1649. doi: 10.1038/s41467-019-09639-3.

9.

Adaptive plasticity of IL-10+ and IL-35+ Treg cells cooperatively promotes tumor T cell exhaustion.

Sawant DV, Yano H, Chikina M, Zhang Q, Liao M, Liu C, Callahan DJ, Sun Z, Sun T, Tabib T, Pennathur A, Corry DB, Luketich JD, Lafyatis R, Chen W, Poholek AC, Bruno TC, Workman CJ, Vignali DAA.

Nat Immunol. 2019 Jun;20(6):724-735. doi: 10.1038/s41590-019-0346-9. Epub 2019 Apr 1.

10.

Fibrinogen-like Protein 1 Is a Major Immune Inhibitory Ligand of LAG-3.

Wang J, Sanmamed MF, Datar I, Su TT, Ji L, Sun J, Chen L, Chen Y, Zhu G, Yin W, Zheng L, Zhou T, Badri T, Yao S, Zhu S, Boto A, Sznol M, Melero I, Vignali DAA, Schalper K, Chen L.

Cell. 2019 Jan 10;176(1-2):334-347.e12. doi: 10.1016/j.cell.2018.11.010. Epub 2018 Dec 20.

PMID:
30580966
11.

Treg Fragility: A Prerequisite for Effective Antitumor Immunity?

Overacre-Delgoffe AE, Vignali DAA.

Cancer Immunol Res. 2018 Aug;6(8):882-887. doi: 10.1158/2326-6066.CIR-18-0066. Review.

12.

B7-H4 Modulates Regulatory CD4+ T Cell Induction and Function via Ligation of a Semaphorin 3a/Plexin A4/Neuropilin-1 Complex.

Podojil JR, Chiang MY, Ifergan I, Copeland R, Liu LN, Maloveste S, Langermann S, Liebenson D, Balabanov R, Chi H, Chen L, Vignali DAA, Miller SD.

J Immunol. 2018 Aug 1;201(3):897-907. doi: 10.4049/jimmunol.1700811. Epub 2018 Jun 13.

13.

Invasive lobular and ductal breast carcinoma differ in immune response, protein translation efficiency and metabolism.

Du T, Zhu L, Levine KM, Tasdemir N, Lee AV, Vignali DAA, Houten BV, Tseng GC, Oesterreich S.

Sci Rep. 2018 May 8;8(1):7205. doi: 10.1038/s41598-018-25357-0.

14.

Opening the Door for Immune Oncology Studies in Invasive Lobular Breast Cancer.

Oesterreich S, Lucas PC, McAuliffe PF, Bruno TC, Vignali DAA.

J Natl Cancer Inst. 2018 Jul 1;110(7):696-698. doi: 10.1093/jnci/djy014. No abstract available.

PMID:
29471462
15.

Treg-specific IL-27Rα deletion uncovers a key role for IL-27 in Treg function to control autoimmunity.

Do J, Kim D, Kim S, Valentin-Torres A, Dvorina N, Jang E, Nagarajavel V, DeSilva TM, Li X, Ting AH, Vignali DAA, Stohlman SA, Baldwin WM 3rd, Min B.

Proc Natl Acad Sci U S A. 2017 Sep 19;114(38):10190-10195. doi: 10.1073/pnas.1703100114. Epub 2017 Sep 5.

16.

LAG3 limits regulatory T cell proliferation and function in autoimmune diabetes.

Zhang Q, Chikina M, Szymczak-Workman AL, Horne W, Kolls JK, Vignali KM, Normolle D, Bettini M, Workman CJ, Vignali DAA.

Sci Immunol. 2017 Mar 31;2(9). pii: eaah4569. doi: 10.1126/sciimmunol.aah4569.

17.

Cutting Edge: CD3 ITAM Diversity Is Required for Optimal TCR Signaling and Thymocyte Development.

Bettini ML, Chou PC, Guy CS, Lee T, Vignali KM, Vignali DAA.

J Immunol. 2017 Sep 1;199(5):1555-1560. doi: 10.4049/jimmunol.1700069. Epub 2017 Jul 21.

18.

Interferon-γ Drives Treg Fragility to Promote Anti-tumor Immunity.

Overacre-Delgoffe AE, Chikina M, Dadey RE, Yano H, Brunazzi EA, Shayan G, Horne W, Moskovitz JM, Kolls JK, Sander C, Shuai Y, Normolle DP, Kirkwood JM, Ferris RL, Delgoffe GM, Bruno TC, Workman CJ, Vignali DAA.

Cell. 2017 Jun 1;169(6):1130-1141.e11. doi: 10.1016/j.cell.2017.05.005. Epub 2017 May 25.

19.

Treg-recruiting microspheres prevent inflammation in a murine model of dry eye disease.

Ratay ML, Glowacki AJ, Balmert SC, Acharya AP, Polat J, Andrews LP, Fedorchak MV, Schuman JS, Vignali DAA, Little SR.

J Control Release. 2017 Jul 28;258:208-217. doi: 10.1016/j.jconrel.2017.05.007. Epub 2017 May 10.

PMID:
28501670
20.

Globule Leukocytes and Other Mast Cells in the Mouse Intestine.

Vogel P, Janke L, Gravano DM, Lu M, Sawant DV, Bush D, Shuyu E, Vignali DAA, Pillai A, Rehg JE.

Vet Pathol. 2018 Jan;55(1):76-97. doi: 10.1177/0300985817705174. Epub 2017 May 11.

PMID:
28494703

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