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Items: 1 to 20 of 76

1.

Proteoglycan 4 deficiency protects against glucose intolerance and fatty liver disease in diet-induced obese mice.

Nahon JE, Hoekstra M, van Harmelen V, Rensen PCN, van Dijk KW, Kooijman S, Van Eck M.

Biochim Biophys Acta Mol Basis Dis. 2018 Nov 15. pii: S0925-4439(18)30468-X. doi: 10.1016/j.bbadis.2018.11.009. [Epub ahead of print]

PMID:
30448542
2.

The prebiotic inulin modulates gut microbiota but does not ameliorate atherosclerosis in hypercholesterolemic APOE*3-Leiden.CETP mice.

Hoving LR, Katiraei S, Pronk A, Heijink M, Vonk KKD, Amghar-El Bouazzaoui F, Vermeulen R, Drinkwaard L, Giera M, van Harmelen V, Willems van Dijk K.

Sci Rep. 2018 Nov 8;8(1):16515. doi: 10.1038/s41598-018-34970-y.

3.

Dietary yeast-derived mannan oligosaccharides have immune-modulatory properties but do not improve high fat diet-induced obesity and glucose intolerance.

Hoving LR, van der Zande HJP, Pronk A, Guigas B, Willems van Dijk K, van Harmelen V.

PLoS One. 2018 May 3;13(5):e0196165. doi: 10.1371/journal.pone.0196165. eCollection 2018.

4.

Dietary Mannan Oligosaccharides Modulate Gut Microbiota, Increase Fecal Bile Acid Excretion, and Decrease Plasma Cholesterol and Atherosclerosis Development.

R Hoving L, Katiraei S, Heijink M, Pronk A, van der Wee-Pals L, Streefland T, Giera M, Willems van Dijk K, van Harmelen V.

Mol Nutr Food Res. 2018 May;62(10):e1700942. doi: 10.1002/mnfr.201700942.

5.

A Restricted Role for FcγR in the Regulation of Adaptive Immunity.

Fransen MF, Benonisson H, van Maren WW, Sow HS, Breukel C, Linssen MM, Claassens JWC, Brouwers C, van der Kaa J, Camps M, Kleinovink JW, Vonk KK, van Heiningen S, Klar N, van Beek L, van Harmelen V, Daxinger L, Nandakumar KS, Holmdahl R, Coward C, Lin Q, Hirose S, Salvatori D, van Hall T, van Kooten C, Mastroeni P, Ossendorp F, Verbeek JS.

J Immunol. 2018 Apr 15;200(8):2615-2626. doi: 10.4049/jimmunol.1700429. Epub 2018 Mar 9.

6.

The Prebiotic Inulin Aggravates Accelerated Atherosclerosis in Hypercholesterolemic APOE*3-Leiden Mice.

Hoving LR, de Vries MR, de Jong RCM, Katiraei S, Pronk A, Quax PHA, van Harmelen V, Willems van Dijk K.

Nutrients. 2018 Feb 3;10(2). pii: E172. doi: 10.3390/nu10020172.

7.

GC-MS Analysis of Medium- and Long-Chain Fatty Acids in Blood Samples.

Hoving LR, Heijink M, van Harmelen V, van Dijk KW, Giera M.

Methods Mol Biol. 2018;1730:257-265. doi: 10.1007/978-1-4939-7592-1_18.

PMID:
29363079
8.

GC-MS Analysis of Short-Chain Fatty Acids in Feces, Cecum Content, and Blood Samples.

Hoving LR, Heijink M, van Harmelen V, van Dijk KW, Giera M.

Methods Mol Biol. 2018;1730:247-256. doi: 10.1007/978-1-4939-7592-1_17.

PMID:
29363078
9.

IgG is elevated in obese white adipose tissue but does not induce glucose intolerance via Fcγ-receptor or complement.

van Dam AD, van Beek L, Pronk ACM, van den Berg SM, Van den Bossche J, de Winther MPJ, Koning F, van Kooten C, Rensen PCN, Boon MR, Verbeek JS, van Dijk KW, van Harmelen V.

Int J Obes (Lond). 2018 Feb;42(2):260-269. doi: 10.1038/ijo.2017.209. Epub 2017 Aug 30.

PMID:
28852207
10.

BMT decreases HFD-induced weight gain associated with decreased preadipocyte number and insulin secretion.

Katiraei S, Hoving LR, van Beek L, Mohamedhoesein S, Carlotti F, van Diepen JA, Rensen PCN, Netea MG, Willems van Dijk K, Berbée JFP, van Harmelen V.

PLoS One. 2017 Apr 26;12(4):e0175524. doi: 10.1371/journal.pone.0175524. eCollection 2017.

11.

Targeting white, brown and perivascular adipose tissue in atherosclerosis development.

van Dam AD, Boon MR, Berbée JFP, Rensen PCN, van Harmelen V.

Eur J Pharmacol. 2017 Dec 5;816:82-92. doi: 10.1016/j.ejphar.2017.03.051. Epub 2017 Mar 24. Review.

12.

Weight loss induced by very low calorie diet is associated with a more beneficial systemic inflammatory profile than by Roux-en-Y gastric bypass.

Lips MA, van Klinken JB, Pijl H, Janssen I, Willems van Dijk K, Koning F, van Harmelen V.

Metabolism. 2016 Nov;65(11):1614-1620. doi: 10.1016/j.metabol.2016.07.013. Epub 2016 Aug 16.

PMID:
27733249
13.

BCG lowers plasma cholesterol levels and delays atherosclerotic lesion progression in mice.

van Dam AD, Bekkering S, Crasborn M, van Beek L, van den Berg SM, Vrieling F, Joosten SA, van Harmelen V, de Winther MPJ, Lütjohann D, Lutgens E, Boon MR, Riksen NP, Rensen PCN, Berbée JFP.

Atherosclerosis. 2016 Aug;251:6-14. doi: 10.1016/j.atherosclerosis.2016.05.031. Epub 2016 May 19.

14.

Identification of a selective glucocorticoid receptor modulator that prevents both diet-induced obesity and inflammation.

van den Heuvel JK, Boon MR, van Hengel I, Peschier-van der Put E, van Beek L, van Harmelen V, van Dijk KW, Pereira AM, Hunt H, Belanoff JK, Rensen PC, Meijer OC.

Br J Pharmacol. 2016 Jun;173(11):1793-804. doi: 10.1111/bph.13477. Epub 2016 Apr 24.

15.

FcRγ-chain deficiency reduces the development of diet-induced obesity.

van Beek L, Vroegrijk IO, Katiraei S, Heemskerk MM, van Dam AD, Kooijman S, Rensen PC, Koning F, Verbeek JS, Willems van Dijk K, van Harmelen V.

Obesity (Silver Spring). 2015 Dec;23(12):2435-44. doi: 10.1002/oby.21309. Epub 2015 Nov 2.

16.

Increased PUFA Content and 5-Lipoxygenase Pathway Expression Are Associated with Subcutaneous Adipose Tissue Inflammation in Obese Women with Type 2 Diabetes.

Heemskerk MM, Giera M, Bouazzaoui FE, Lips MA, Pijl H, van Dijk KW, van Harmelen V.

Nutrients. 2015 Sep 11;7(9):7676-90. doi: 10.3390/nu7095362.

17.

Splenic autonomic denervation increases inflammatory status but does not aggravate atherosclerotic lesion development.

Kooijman S, Meurs I, van Beek L, Khedoe PP, Giezekamp A, Pike-Overzet K, Cailotto C, van der Vliet J, van Harmelen V, Boeckxstaens G, Berbée JF, Rensen PC.

Am J Physiol Heart Circ Physiol. 2015 Aug 15;309(4):H646-54. doi: 10.1152/ajpheart.00787.2014. Epub 2015 Jun 19.

18.

Reanalysis of mGWAS results and in vitro validation show that lactate dehydrogenase interacts with branched-chain amino acid metabolism.

Heemskerk MM, van Harmelen VJ, van Dijk KW, van Klinken JB.

Eur J Hum Genet. 2016 Jan;24(1):142-5. doi: 10.1038/ejhg.2015.106. Epub 2015 May 27.

19.

The limited storage capacity of gonadal adipose tissue directs the development of metabolic disorders in male C57Bl/6J mice.

van Beek L, van Klinken JB, Pronk AC, van Dam AD, Dirven E, Rensen PC, Koning F, Willems van Dijk K, van Harmelen V.

Diabetologia. 2015 Jul;58(7):1601-9. doi: 10.1007/s00125-015-3594-8. Epub 2015 May 12.

20.

Chronic helminth infection and helminth-derived egg antigens promote adipose tissue M2 macrophages and improve insulin sensitivity in obese mice.

Hussaarts L, García-Tardón N, van Beek L, Heemskerk MM, Haeberlein S, van der Zon GC, Ozir-Fazalalikhan A, Berbée JF, Willems van Dijk K, van Harmelen V, Yazdanbakhsh M, Guigas B.

FASEB J. 2015 Jul;29(7):3027-39. doi: 10.1096/fj.14-266239. Epub 2015 Apr 7.

PMID:
25852044

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