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Items: 9


Mitochondria sustain store-operated currents in colon cancer cells but not in normal colonic cells: reversal by non-steroidal anti-inflammatory drugs.

Hernández-Morales M, Sobradillo D, Valero RA, Muñoz E, Ubierna D, Moyer MP, Núñez L, Villalobos C.

Oncotarget. 2017 Jul 21;8(33):55332-55352. doi: 10.18632/oncotarget.19430. eCollection 2017 Aug 15.


DYNLT (Tctex-1) forms a tripartite complex with dynein intermediate chain and RagA, hence linking this small GTPase to the dynein motor.

Merino-Gracia J, García-Mayoral MF, Rapali P, Valero RA, Bruix M, Rodríguez-Crespo I.

FEBS J. 2015 Oct;282(20):3945-58. doi: 10.1111/febs.13388. Epub 2015 Aug 20.


Protein palmitoylation and subcellular trafficking.

Aicart-Ramos C, Valero RA, Rodriguez-Crespo I.

Biochim Biophys Acta. 2011 Dec;1808(12):2981-94. doi: 10.1016/j.bbamem.2011.07.009. Epub 2011 Jul 23. Review.


Nonsteroidal anti-inflammatory drugs inhibit vascular smooth muscle cell proliferation by enabling the Ca2+-dependent inactivation of calcium release-activated calcium/orai channels normally prevented by mitochondria.

Muñoz E, Valero RA, Quintana A, Hoth M, Núñez L, Villalobos C.

J Biol Chem. 2011 May 6;286(18):16186-96. doi: 10.1074/jbc.M110.198952. Epub 2011 Mar 14.


Structural determinants allowing endolysosomal sorting and degradation of endosomal GTPases.

Valero RA, Oeste CL, Stamatakis K, Ramos I, Herrera M, Boya P, Pérez-Sala D.

Traffic. 2010 Sep;11(9):1221-33. doi: 10.1111/j.1600-0854.2010.01091.x. Epub 2010 Jun 21.


RhoA-ROCK and p38MAPK-MSK1 mediate vitamin D effects on gene expression, phenotype, and Wnt pathway in colon cancer cells.

Ordóñez-Morán P, Larriba MJ, Pálmer HG, Valero RA, Barbáchano A, Duñach M, de Herreros AG, Villalobos C, Berciano MT, Lafarga M, Muñoz A.

J Cell Biol. 2008 Nov 17;183(4):697-710. doi: 10.1083/jcb.200803020.


Mitochondrial Ca2+ overload underlies Abeta oligomers neurotoxicity providing an unexpected mechanism of neuroprotection by NSAIDs.

Sanz-Blasco S, Valero RA, Rodríguez-Crespo I, Villalobos C, Núñez L.

PLoS One. 2008 Jul 23;3(7):e2718. doi: 10.1371/journal.pone.0002718.


The role of mitochondrial potential in control of calcium signals involved in cell proliferation.

Valero RA, Senovilla L, Núñez L, Villalobos C.

Cell Calcium. 2008 Sep;44(3):259-69. doi: 10.1016/j.ceca.2007.12.002. Epub 2008 Feb 1.


Cell proliferation depends on mitochondrial Ca2+ uptake: inhibition by salicylate.

Núñez L, Valero RA, Senovilla L, Sanz-Blasco S, García-Sancho J, Villalobos C.

J Physiol. 2006 Feb 15;571(Pt 1):57-73. Epub 2005 Dec 8.

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