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Items: 1 to 20 of 34

1.

Differential regulation of Ca2+ influx by ORAI channels mediates enamel mineralization.

Eckstein M, Vaeth M, Aulestia FJ, Costiniti V, Kassam SN, Bromage TG, Pedersen P, Issekutz T, Idaghdour Y, Moursi AM, Feske S, Lacruz RS.

Sci Signal. 2019 Apr 23;12(578). pii: eaav4663. doi: 10.1126/scisignal.aav4663.

PMID:
31015290
2.

Tissue resident and follicular Treg cell differentiation is regulated by CRAC channels.

Vaeth M, Wang YH, Eckstein M, Yang J, Silverman GJ, Lacruz RS, Kannan K, Feske S.

Nat Commun. 2019 Mar 12;10(1):1183. doi: 10.1038/s41467-019-08959-8.

3.

ORAI1, STIM1/2, and RYR1 shape subsecond Ca2+ microdomains upon T cell activation.

Diercks BP, Werner R, Weidemüller P, Czarniak F, Hernandez L, Lehmann C, Rosche A, Krüger A, Kaufmann U, Vaeth M, Failla AV, Zobiak B, Kandil FI, Schetelig D, Ruthenbeck A, Meier C, Lodygin D, Flügel A, Ren D, Wolf IMA, Feske S, Guse AH.

Sci Signal. 2018 Dec 18;11(561). pii: eaat0358. doi: 10.1126/scisignal.aat0358.

PMID:
30563862
4.

STIM1 and STIM2 Mediate Cancer-Induced Inflammation in T Cell Acute Lymphoblastic Leukemia.

Saint Fleur-Lominy S, Maus M, Vaeth M, Lange I, Zee I, Suh D, Liu C, Wu X, Tikhonova A, Aifantis I, Feske S.

Cell Rep. 2018 Sep 11;24(11):3045-3060.e5. doi: 10.1016/j.celrep.2018.08.030.

5.

Functional Interrogation of Primary Human T Cells via CRISPR Genetic Editing.

Chen X, Kozhaya L, Tastan C, Placek L, Dogan M, Horne M, Abblett R, Karhan E, Vaeth M, Feske S, Unutmaz D.

J Immunol. 2018 Sep 1;201(5):1586-1598. doi: 10.4049/jimmunol.1701616. Epub 2018 Jul 18.

PMID:
30021769
6.

Ion channelopathies of the immune system.

Vaeth M, Feske S.

Curr Opin Immunol. 2018 Jun;52:39-50. doi: 10.1016/j.coi.2018.03.021. Epub 2018 Apr 7. Review.

7.

NFAT control of immune function: New Frontiers for an Abiding Trooper.

Vaeth M, Feske S.

F1000Res. 2018 Mar 2;7:260. doi: 10.12688/f1000research.13426.1. eCollection 2018. Review.

8.

ORAI1 mutations abolishing store-operated Ca2+ entry cause anhidrotic ectodermal dysplasia with immunodeficiency.

Lian J, Cuk M, Kahlfuss S, Kozhaya L, Vaeth M, Rieux-Laucat F, Picard C, Benson MJ, Jakovcevic A, Bilic K, Martinac I, Stathopulos P, Kacskovics I, Vraetz T, Speckmann C, Ehl S, Issekutz T, Unutmaz D, Feske S.

J Allergy Clin Immunol. 2018 Oct;142(4):1297-1310.e11. doi: 10.1016/j.jaci.2017.10.031. Epub 2017 Nov 16.

PMID:
29155098
9.

Store-Operated Ca2+ Entry Controls Clonal Expansion of T Cells through Metabolic Reprogramming.

Vaeth M, Maus M, Klein-Hessling S, Freinkman E, Yang J, Eckstein M, Cameron S, Turvey SE, Serfling E, Berberich-Siebelt F, Possemato R, Feske S.

Immunity. 2017 Oct 17;47(4):664-679.e6. doi: 10.1016/j.immuni.2017.09.003. Epub 2017 Oct 11.

10.

NFATc1 controls the cytotoxicity of CD8+ T cells.

Klein-Hessling S, Muhammad K, Klein M, Pusch T, Rudolf R, Flöter J, Qureischi M, Beilhack A, Vaeth M, Kummerow C, Backes C, Schoppmeyer R, Hahn U, Hoth M, Bopp T, Berberich-Siebelt F, Patra A, Avots A, Müller N, Schulze A, Serfling E.

Nat Commun. 2017 Sep 11;8(1):511. doi: 10.1038/s41467-017-00612-6.

11.

Store-operated Ca2+ entry controls ameloblast cell function and enamel development.

Eckstein M, Vaeth M, Fornai C, Vinu M, Bromage TG, Nurbaeva MK, Sorge JL, Coelho PG, Idaghdour Y, Feske S, Lacruz RS.

JCI Insight. 2017 Mar 23;2(6):e91166. doi: 10.1172/jci.insight.91166.

12.

ORAI2 modulates store-operated calcium entry and T cell-mediated immunity.

Vaeth M, Yang J, Yamashita M, Zee I, Eckstein M, Knosp C, Kaufmann U, Karoly Jani P, Lacruz RS, Flockerzi V, Kacskovics I, Prakriya M, Feske S.

Nat Commun. 2017 Mar 15;8:14714. doi: 10.1038/ncomms14714.

13.

Store-operated Ca2+ entry regulates Ca2+-activated chloride channels and eccrine sweat gland function.

Concepcion AR, Vaeth M, Wagner LE 2nd, Eckstein M, Hecht L, Yang J, Crottes D, Seidl M, Shin HP, Weidinger C, Cameron S, Turvey SE, Issekutz T, Meyts I, Lacruz RS, Cuk M, Yule DI, Feske S.

J Clin Invest. 2016 Nov 1;126(11):4303-4318. doi: 10.1172/JCI89056. Epub 2016 Oct 10.

14.

Exogenous TNFR2 activation protects from acute GvHD via host T reg cell expansion.

Chopra M, Biehl M, Steinfatt T, Brandl A, Kums J, Amich J, Vaeth M, Kuen J, Holtappels R, Podlech J, Mottok A, Kraus S, Jordán-Garrote AL, Bäuerlein CA, Brede C, Ribechini E, Fick A, Seher A, Polz J, Ottmüller KJ, Baker J, Nishikii H, Ritz M, Mattenheimer K, Schwinn S, Winter T, Schäfer V, Krappmann S, Einsele H, Müller TD, Reddehase MJ, Lutz MB, Männel DN, Berberich-Siebelt F, Wajant H, Beilhack A.

J Exp Med. 2016 Aug 22;213(9):1881-900. doi: 10.1084/jem.20151563. Epub 2016 Aug 15.

15.

Identification of PGAM5 as a Mammalian Protein Histidine Phosphatase that Plays a Central Role to Negatively Regulate CD4(+) T Cells.

Panda S, Srivastava S, Li Z, Vaeth M, Fuhs SR, Hunter T, Skolnik EY.

Mol Cell. 2016 Aug 4;63(3):457-69. doi: 10.1016/j.molcel.2016.06.021. Epub 2016 Jul 21.

16.

Store-Operated Ca(2+) Entry in Follicular T Cells Controls Humoral Immune Responses and Autoimmunity.

Vaeth M, Eckstein M, Shaw PJ, Kozhaya L, Yang J, Berberich-Siebelt F, Clancy R, Unutmaz D, Feske S.

Immunity. 2016 Jun 21;44(6):1350-64. doi: 10.1016/j.immuni.2016.04.013. Epub 2016 May 31.

17.

Ca2+ Signaling but Not Store-Operated Ca2+ Entry Is Required for the Function of Macrophages and Dendritic Cells.

Vaeth M, Zee I, Concepcion AR, Maus M, Shaw P, Portal-Celhay C, Zahra A, Kozhaya L, Weidinger C, Philips J, Unutmaz D, Feske S.

J Immunol. 2015 Aug 1;195(3):1202-17. doi: 10.4049/jimmunol.1403013. Epub 2015 Jun 24.

18.

STIM1 controls T cell-mediated immune regulation and inflammation in chronic infection.

Desvignes L, Weidinger C, Shaw P, Vaeth M, Ribierre T, Liu M, Fergus T, Kozhaya L, McVoy L, Unutmaz D, Ernst JD, Feske S.

J Clin Invest. 2015 Jun;125(6):2347-62. doi: 10.1172/JCI80273. Epub 2015 May 4.

19.

TCAIM decreases T cell priming capacity of dendritic cells by inhibiting TLR-induced Ca2+ influx and IL-2 production.

Vogel SZ, Schlickeiser S, Jürchott K, Akyuez L, Schumann J, Appelt C, Vogt K, Schröder M, Vaeth M, Berberich-Siebelt F, Lutz MB, Grütz G, Sawitzki B.

J Immunol. 2015 Apr 1;194(7):3136-46. doi: 10.4049/jimmunol.1400713. Epub 2015 Mar 6.

20.

NFAT1 deficit and NFAT2 deficit attenuate EAE via different mechanisms.

Dietz L, Frommer F, Vogel AL, Vaeth M, Serfling E, Waisman A, Buttmann M, Berberich-Siebelt F.

Eur J Immunol. 2015 May;45(5):1377-89. doi: 10.1002/eji.201444638. Epub 2015 Feb 19.

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