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Items: 1 to 20 of 644

1.

Impact of Porous Excipients on the Manufacturability and Product Performance of Solid Self-Emulsifying Drug Delivery Systems.

Beringhs AO, Minatovicz BC, Zhang GGZ, Chaudhuri B, Lu X.

AAPS PharmSciTech. 2018 Sep 14. doi: 10.1208/s12249-018-1178-x. [Epub ahead of print]

PMID:
30218264
2.

Manufacturing and characterization of long-acting levonorgestrel intrauterine systems.

Bao Q, Gu B, Price CF, Zou Y, Wang Y, Kozak D, Choi S, Burgess DJ.

Int J Pharm. 2018 Sep 5;550(1-2):447-454. doi: 10.1016/j.ijpharm.2018.09.004. [Epub ahead of print]

PMID:
30195080
3.

Applications of the tunable diode laser absorption spectroscopy (TDLAS): In-process estimation of primary drying heterogeneity and product temperature during lyophilization.

Sharma P, Kessler WJ, Bogner R, Thakur M, Pikal MJ.

J Pharm Sci. 2018 Aug 13. pii: S0022-3549(18)30500-8. doi: 10.1016/j.xphs.2018.07.031. [Epub ahead of print]

PMID:
30114403
4.

Mechanisms by which crystalline mannitol improves the reconstitution time of high concentration lyophilized protein formulations.

Kulkarni SS, Suryanarayanan R, Rinella JV Jr, Bogner RH.

Eur J Pharm Biopharm. 2018 Oct;131:70-81. doi: 10.1016/j.ejpb.2018.07.022. Epub 2018 Jul 26.

PMID:
30056143
5.

Freezing of aqueous solutions and chemical stability of amorphous pharmaceuticals: water clusters hypothesis.

Shalaev E, Soper A, Zeitler JA, Ohtake S, Roberts CJ, Pikal MJ, Wu K, Boldyreva E.

J Pharm Sci. 2018 Jul 25. pii: S0022-3549(18)30453-2. doi: 10.1016/j.xphs.2018.07.018. [Epub ahead of print]

6.

Influence of Manufacturing Process Variables on the Properties of Ophthalmic Ointments of Tobramycin.

Patere S, Newman B, Wang Y, Choi S, Vora S, Ma AWK, Jay M, Lu X.

Pharm Res. 2018 Jul 25;35(9):179. doi: 10.1007/s11095-018-2462-x.

PMID:
30046909
7.

Binding and backbone dynamics of protein under topological constraint: calmodulin as a model system.

Katyal P, Yang Y, Fu YJ, Iandosca J, Vinogradova O, Lin Y.

Chem Commun (Camb). 2018 Aug 7;54(64):8917-8920. doi: 10.1039/c8cc03977a.

PMID:
30043775
8.

Small molecule scaffolds that disrupt the Rev1-CT/RIR protein-protein interaction.

Ozen Z, Dash RC, McCarthy KR, Chow SA, Rizzo AA, Korzhnev DM, Hadden MK.

Bioorg Med Chem. 2018 Aug 7;26(14):4301-4309. doi: 10.1016/j.bmc.2018.07.029. Epub 2018 Jul 19.

PMID:
30037752
9.

Quantification of Moisture-Induced Cohesion in Pharmaceutical Mixtures.

Mukherjee R, Sen K, Fontana L, Mao C, Chaudhuri B.

J Pharm Sci. 2018 Jul 12. pii: S0022-3549(18)30408-8. doi: 10.1016/j.xphs.2018.07.006. [Epub ahead of print]

PMID:
30017891
10.

The Effect of Low Ionic Strength on Diffusion and Viscosity of Monoclonal Antibodies.

Pindrus MA, Shire SJ, Yadav S, Kalonia DS.

Mol Pharm. 2018 Aug 6;15(8):3133-3142. doi: 10.1021/acs.molpharmaceut.8b00210. Epub 2018 Jul 24.

PMID:
29996057
11.

Liver metabolomics in a mouse model of erythropoietic protoporphyria.

Wang P, Sachar M, Guo GL, Shehu AI, Lu J, Zhong XB, Ma X.

Biochem Pharmacol. 2018 Aug;154:474-481. doi: 10.1016/j.bcp.2018.06.011. Epub 2018 Jun 12.

PMID:
29906468
12.

Consequences of Phenytoin Exposure on Hepatic Cytochrome P450 Expression during Postnatal Liver Maturation in Mice.

Piekos SC, Chen L, Wang P, Shi J, Yaqoob S, Zhu HJ, Ma X, Zhong XB.

Drug Metab Dispos. 2018 Aug;46(8):1241-1250. doi: 10.1124/dmd.118.080861. Epub 2018 Jun 8.

PMID:
29884652
13.

Probing seco-steroid inhibition of the hedgehog signaling pathway.

Thompson EN, Sail V, Raccuia DS, Hadden MK.

Mol Cell Biochem. 2018 Jun 6. doi: 10.1007/s11010-018-3374-0. [Epub ahead of print]

PMID:
29876765
14.

A metadynamic approach to understand the recognition mechanism of the histone H3 tail with the ATRXADD domain.

Dash RC, Zaino AM, Hadden MK.

Biochim Biophys Acta Gene Regul Mech. 2018 Jun;1861(6):594-602. doi: 10.1016/j.bbagrm.2018.05.001. Epub 2018 May 3.

PMID:
29730439
15.

A Transcriptional Regulatory Network Containing Nuclear Receptors and Long Noncoding RNAs Controls Basal and Drug-Induced Expression of Cytochrome P450s in HepaRG Cells.

Chen L, Bao Y, Piekos SC, Zhu K, Zhang L, Zhong XB.

Mol Pharmacol. 2018 Jul;94(1):749-759. doi: 10.1124/mol.118.112235. Epub 2018 Apr 24.

PMID:
29691280
16.

Electrocardiographic effects of hawthorn (Crataegus oxyacantha) in healthy volunteers: A randomized controlled trial.

Trexler SE, Nguyen E, Gromek SM, Balunas MJ, Baker WL.

Phytother Res. 2018 Aug;32(8):1642-1646. doi: 10.1002/ptr.6094. Epub 2018 Apr 19.

PMID:
29672935
17.

A Novel Fibroblast Growth Factor 15 Dependent- and Bile Acid Independent-Promotion of Liver Regeneration in Mice.

Kong B, Sun R, Huang M, Chow MD, Zhong XB, Xie W, Lee YH, Guo GL.

Hepatology. 2018 Apr 19. doi: 10.1002/hep.30041. [Epub ahead of print]

PMID:
29672888
18.

Propagating annotations of molecular networks using in silico fragmentation.

da Silva RR, Wang M, Nothias LF, van der Hooft JJJ, Caraballo-Rodríguez AM, Fox E, Balunas MJ, Klassen JL, Lopes NP, Dorrestein PC.

PLoS Comput Biol. 2018 Apr 18;14(4):e1006089. doi: 10.1371/journal.pcbi.1006089. eCollection 2018 Apr.

19.

Effects of a Single Intra-Articular Injection of a Microsphere Formulation of Triamcinolone Acetonide on Knee Osteoarthritis Pain: A Double-Blinded, Randomized, Placebo-Controlled, Multinational Study.

Conaghan PG, Hunter DJ, Cohen SB, Kraus VB, Berenbaum F, Lieberman JR, Jones DG, Spitzer AI, Jevsevar DS, Katz NP, Burgess DJ, Lufkin J, Johnson JR, Bodick N; FX006-2014-008 Participating Investigators.

J Bone Joint Surg Am. 2018 Apr 18;100(8):666-677. doi: 10.2106/JBJS.17.00154.

20.

Advances in drug delivery related biosensors and medical devices.

Shen J, Burgess DJ.

Int J Pharm. 2018 Jun 15;544(2):307-308. doi: 10.1016/j.ijpharm.2018.03.051. Epub 2018 Mar 28. No abstract available.

PMID:
29601976

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