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Items: 1 to 20 of 56


Suppression of TGFβ-mediated conversion of endothelial cells and fibroblasts into cancer associated (myo)fibroblasts via HDAC inhibition.

Kim DJ, Dunleavey JM, Xiao L, Ollila DW, Troester MA, Otey CA, Li W, Barker TH, Dudley AC.

Br J Cancer. 2018 May;118(10):1359-1368. doi: 10.1038/s41416-018-0072-3. Epub 2018 Apr 26.


Enhancing clot properties through fibrin-specific self-cross-linked PEG side-chain microgels.

Welsch N, Brown AC, Barker TH, Lyon LA.

Colloids Surf B Biointerfaces. 2018 Jun 1;166:89-97. doi: 10.1016/j.colsurfb.2018.03.003. Epub 2018 Mar 2.


The fibrotic tumor stroma.

Yamauchi M, Barker TH, Gibbons DL, Kurie JM.

J Clin Invest. 2018 Jan 2;128(1):16-25. doi: 10.1172/JCI93554. Epub 2018 Jan 2.


Hydrogels with precisely controlled integrin activation dictate vascular patterning and permeability.

Li S, Nih LR, Bachman H, Fei P, Li Y, Nam E, Dimatteo R, Carmichael ST, Barker TH, Segura T.

Nat Mater. 2017 Sep;16(9):953-961. doi: 10.1038/nmat4954. Epub 2017 Aug 7.


Detection of an Integrin-Binding Mechanoswitch within Fibronectin during Tissue Formation and Fibrosis.

Cao L, Nicosia J, Larouche J, Zhang Y, Bachman H, Brown AC, Holmgren L, Barker TH.

ACS Nano. 2017 Jul 25;11(7):7110-7117. doi: 10.1021/acsnano.7b02755. Epub 2017 Jul 12.


The provisional matrix: setting the stage for tissue repair outcomes.

Barker TH, Engler AJ.

Matrix Biol. 2017 Jul;60-61:1-4. doi: 10.1016/j.matbio.2017.04.003. Review.


Charge segregation in weakly ionized microgels.

Hyatt JS, Douglas AM, Stanley C, Do C, Barker TH, Fernández-Nieves A.

Phys Rev E. 2017 Jan;95(1-1):012608. doi: 10.1103/PhysRevE.95.012608. Epub 2017 Jan 19.


Dynamic assembly of ultrasoft colloidal networks enables cell invasion within restrictive fibrillar polymers.

Douglas AM, Fragkopoulos AA, Gaines MK, Lyon LA, Fernandez-Nieves A, Barker TH.

Proc Natl Acad Sci U S A. 2017 Jan 31;114(5):885-890. doi: 10.1073/pnas.1607350114. Epub 2017 Jan 18.


A novel platelet lysate hydrogel for endothelial cell and mesenchymal stem cell-directed neovascularization.

Robinson ST, Douglas AM, Chadid T, Kuo K, Rajabalan A, Li H, Copland IB, Barker TH, Galipeau J, Brewster LP.

Acta Biomater. 2016 May;36:86-98. doi: 10.1016/j.actbio.2016.03.002. Epub 2016 Mar 4.


Fibrin Network Changes in Neonates after Cardiopulmonary Bypass.

Brown AC, Hannan RT, Timmins LH, Fernandez JD, Barker TH, Guzzetta NA.

Anesthesiology. 2016 May;124(5):1021-31. doi: 10.1097/ALN.0000000000001058. Erratum in: Anesthesiology. 2016 Sep;125(3):610.


Conformational coupling of integrin and Thy-1 regulates Fyn priming and fibroblast mechanotransduction.

Fiore VF, Strane PW, Bryksin AV, White ES, Hagood JS, Barker TH.

J Cell Biol. 2015 Oct 12;211(1):173-90. doi: 10.1083/jcb.201505007.


Chondroitin Sulfate Glycosaminoglycan Hydrogels Create Endogenous Niches for Neural Stem Cells.

Karumbaiah L, Enam SF, Brown AC, Saxena T, Betancur MI, Barker TH, Bellamkonda RV.

Bioconjug Chem. 2015 Dec 16;26(12):2336-49. doi: 10.1021/acs.bioconjchem.5b00397. Epub 2015 Oct 20.


Integrin α3β1 Binding to Fibronectin Is Dependent on the Ninth Type III Repeat.

Brown AC, Dysart MM, Clarke KC, Stabenfeldt SE, Barker TH.

J Biol Chem. 2015 Oct 16;290(42):25534-47. doi: 10.1074/jbc.M115.656702. Epub 2015 Aug 28.


Utilizing Fibronectin Integrin-Binding Specificity to Control Cellular Responses.

Bachman H, Nicosia J, Dysart M, Barker TH.

Adv Wound Care (New Rochelle). 2015 Aug 1;4(8):501-511. Review.


Molecular interference of fibrin's divalent polymerization mechanism enables modulation of multiscale material properties.

Brown AC, Baker SR, Douglas AM, Keating M, Alvarez-Elizondo MB, Botvinick EL, Guthold M, Barker TH.

Biomaterials. 2015 May;49:27-36. doi: 10.1016/j.biomaterials.2015.01.010. Epub 2015 Feb 11.


The evolution of fibrin-specific targeting strategies.

Stefanelli VL, Barker TH.

J Mater Chem B. 2015 Feb 21;3(7):1177-1186. doi: 10.1039/C4TB01769B. Epub 2015 Jan 13.


Synergistic effects of particulate matter and substrate stiffness on epithelial-to-mesenchymal transition.

Barker TH, Dysart MM, Brown AC, Douglas AM, Fiore VF, Russell AG; HEI Health Review Committee.

Res Rep Health Eff Inst. 2014 Nov;(182):3-41.


One primer to rule them all: universal primer that adds BBa_B0034 ribosomal binding site to any coding standard 10 BioBrick.

Bryksin AV, Bachman HN, Cooper SW, Balavijayan T, Blackstone RM, Du H, Jenkins JP, Haynes CL, Siemer JL, Fiore VF, Barker TH.

ACS Synth Biol. 2014 Dec 19;3(12):956-9. doi: 10.1021/sb500047r.


Platelet mechanosensing of substrate stiffness during clot formation mediates adhesion, spreading, and activation.

Qiu Y, Brown AC, Myers DR, Sakurai Y, Mannino RG, Tran R, Ahn B, Hardy ET, Kee MF, Kumar S, Bao G, Barker TH, Lam WA.

Proc Natl Acad Sci U S A. 2014 Oct 7;111(40):14430-5. doi: 10.1073/pnas.1322917111. Epub 2014 Sep 22.


Environmental particulate (PM2.5) augments stiffness-induced alveolar epithelial cell mechanoactivation of transforming growth factor beta.

Dysart MM, Galvis BR, Russell AG, Barker TH.

PLoS One. 2014 Sep 16;9(9):e106821. doi: 10.1371/journal.pone.0106821. eCollection 2014.

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