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  • Showing results for starfield[Title] AND pattern[Title] AND cerebral[Title] AND fat[Title] AND embolism[Title] AND bone[Title] AND marrow[Title] AND necrosis[Title]. Your search for the starfield pattern of cerebral fat embolism from bone marrow necrosis in sickl retrieved no results.
Neurohospitalist. 2015 Apr;5(2):74-6. doi: 10.1177/1941874414554300.

The "starfield" pattern of cerebral fat embolism from bone marrow necrosis in sickle cell crisis.

Author information

1
Department of Neurology, Jacksonville, FL, USA ; Department of Neurology, Jacksonville, FL, USA.
2
Department of Laboratory Medicine and Pathology, Jacksonville, FL, USA.
3
Department of Neurology, Jacksonville, FL, USA.
4
Department of Neurology, Jacksonville, FL, USA ; Department of Critical Care at Mayo Clinic, Jacksonville, FL, USA ; Department of Neurosurgery, Jacksonville, FL, USA.

Abstract

Sickle cell disease may manifest with cerebrovascular and systemic complications. Sickle crisis that results in avascular necrosis of long bones with resultant cerebral fat embolism syndrome is rare and has a characteristic "starfield" pattern on MRI. This "starfield" MRI pattern should raise suspicion for sickle cell crisis in patients without a known history of the disease, which can lead to earlier sickle cell red blood cell exchange transfusion and treatment. We present a case of a male who presented emergently with acute seizure, coma with a characteristic MRI pattern, which lead to the diagnosis of avascular bone marrow necrosis and cerebral fat embolism syndrome from sickle cell crisis.

KEYWORDS:

bone marrow necrosis; cerebral fat embolism syndrome; magnetic resonance imaging (MRI); seizure; sickle cell disease

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