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Items: 20


Dietary oxalate and kidney stone formation.

Mitchell T, Kumar P, Reddy T, Wood KD, Knight J, Assimos DG, Holmes RP.

Am J Physiol Renal Physiol. 2019 Mar 1;316(3):F409-F413. doi: 10.1152/ajprenal.00373.2018. Epub 2018 Dec 19.


Stay in the Loop: New Insights about Randall's Plaques and Stone Disease.

Mitchell T.

Am J Physiol Renal Physiol. 2018 Sep 19. doi: 10.1152/ajprenal.00409.2018. [Epub ahead of print] No abstract available.


Oxalate induces mitochondrial dysfunction and disrupts redox homeostasis in a human monocyte derived cell line.

Patel M, Yarlagadda V, Adedoyin O, Saini V, Assimos DG, Holmes RP, Mitchell T.

Redox Biol. 2018 May;15:207-215. doi: 10.1016/j.redox.2017.12.003. Epub 2017 Dec 15.


Pleiotropic effects of 4-hydroxynonenal on oxidative burst and phagocytosis in neutrophils.

Chacko BK, Wall SB, Kramer PA, Ravi S, Mitchell T, Johnson MS, Wilson L, Barnes S, Landar A, Darley-Usmar VM.

Redox Biol. 2016 Oct;9:57-66. doi: 10.1016/j.redox.2016.06.003. Epub 2016 Jun 23.


Monocyte Mitochondrial Function in Calcium Oxalate Stone Formers.

Williams J, Holmes RP, Assimos DG, Mitchell T.

Urology. 2016 Jul;93:224.e1-6. doi: 10.1016/j.urology.2016.03.004. Epub 2016 Mar 10.


The Bioenergetic Health Index is a sensitive measure of oxidative stress in human monocytes.

Chacko BK, Zhi D, Darley-Usmar VM, Mitchell T.

Redox Biol. 2016 Aug;8:43-50. doi: 10.1016/j.redox.2015.12.008. Epub 2015 Dec 24.


Hemoglobin-associated oxidative stress in the pericardial compartment of postoperative cardiac surgery patients.

Kramer PA, Chacko BK, Ravi S, Johnson MS, Mitchell T, Barnes S, Arabshahi A, Dell'Italia LJ, George DJ, Steele C, George JF, Darley-Usmar VM, Melby SJ.

Lab Invest. 2015 Feb;95(2):132-41. doi: 10.1038/labinvest.2014.144. Epub 2014 Dec 1.


The Bioenergetic Health Index: a new concept in mitochondrial translational research.

Chacko BK, Kramer PA, Ravi S, Benavides GA, Mitchell T, Dranka BP, Ferrick D, Singal AK, Ballinger SW, Bailey SM, Hardy RW, Zhang J, Zhi D, Darley-Usmar VM.

Clin Sci (Lond). 2014 Sep;127(6):367-73. doi: 10.1042/CS20140101. Review.


Mitochondria in monocytes and macrophages-implications for translational and basic research.

Ravi S, Mitchell T, Kramer P, Chacko B, Darley-Usmar VM.

Int J Biochem Cell Biol. 2014 Aug;53:202-207. doi: 10.1016/j.biocel.2014.05.019. Epub 2014 May 23.


Bioenergetics and the oxidative burst: protocols for the isolation and evaluation of human leukocytes and platelets.

Kramer PA, Chacko BK, Ravi S, Johnson MS, Mitchell T, Darley-Usmar VM.

J Vis Exp. 2014 Mar 27;(85). doi: 10.3791/51301.


Dysfunctional mitochondrial bioenergetics and oxidative stress in Akita(+/Ins2)-derived β-cells.

Mitchell T, Johnson MS, Ouyang X, Chacko BK, Mitra K, Lei X, Gai Y, Moore DR, Barnes S, Zhang J, Koizumi A, Ramanadham S, Darley-Usmar VM.

Am J Physiol Endocrinol Metab. 2013 Sep 1;305(5):E585-99. doi: 10.1152/ajpendo.00093.2013. Epub 2013 Jul 2.


Mitochondrially targeted compounds and their impact on cellular bioenergetics.

Reily C, Mitchell T, Chacko BK, Benavides G, Murphy MP, Darley-Usmar V.

Redox Biol. 2013;1(1):86-93.


Convergent mechanisms for dysregulation of mitochondrial quality control in metabolic disease: implications for mitochondrial therapeutics.

Mitchell T, Chacko B, Ballinger SW, Bailey SM, Zhang J, Darley-Usmar V.

Biochem Soc Trans. 2013 Feb 1;41(1):127-33. doi: 10.1042/BST20120231. Review.


Controlling radicals in the powerhouse: development of MitoSOD.

Mitchell T, Chacko BK, Darley-Usmar V.

Chem Biol. 2012 Oct 26;19(10):1217-8. doi: 10.1016/j.chembiol.2012.10.004.


Metabolic syndrome and mitochondrial dysfunction: insights from preclinical studies with a mitochondrially targeted antioxidant.

Mitchell T, Darley-Usmar V.

Free Radic Biol Med. 2012 Mar 1;52(5):838-40. doi: 10.1016/j.freeradbiomed.2011.12.014. Epub 2011 Dec 22. No abstract available.


Generation and characterization of a novel kidney-specific manganese superoxide dismutase knockout mouse.

Parajuli N, Marine A, Simmons S, Saba H, Mitchell T, Shimizu T, Shirasawa T, Macmillan-Crow LA.

Free Radic Biol Med. 2011 Jul 15;51(2):406-16. doi: 10.1016/j.freeradbiomed.2011.04.024. Epub 2011 Apr 17.


The mitochondria-targeted antioxidant mitoquinone protects against cold storage injury of renal tubular cells and rat kidneys.

Mitchell T, Rotaru D, Saba H, Smith RA, Murphy MP, MacMillan-Crow LA.

J Pharmacol Exp Ther. 2011 Mar;336(3):682-92. doi: 10.1124/jpet.110.176743. Epub 2010 Dec 15. Erratum in: J Pharmacol Exp Ther. 2012 Aug;342(2):596.


Role of mitochondrial-derived oxidants in renal tubular cell cold-storage injury.

Mitchell T, Saba H, Laakman J, Parajuli N, MacMillan-Crow LA.

Free Radic Biol Med. 2010 Nov 1;49(8):1273-82. doi: 10.1016/j.freeradbiomed.2010.07.012. Epub 2010 Jul 24.


Alteration of renal respiratory Complex-III during experimental type-1 diabetes.

Munusamy S, Saba H, Mitchell T, Megyesi JK, Brock RW, Macmillan-Crow LA.

BMC Endocr Disord. 2009 Jan 23;9:2. doi: 10.1186/1472-6823-9-2.


Manganese porphyrin reduces renal injury and mitochondrial damage during ischemia/reperfusion.

Saba H, Batinic-Haberle I, Munusamy S, Mitchell T, Lichti C, Megyesi J, MacMillan-Crow LA.

Free Radic Biol Med. 2007 May 15;42(10):1571-8. Epub 2007 Feb 28.

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