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Items: 1 to 20 of 173

1.

Characterization of the two conformations adopted by the T3SS inner-membrane protein PrgK.

Bergeron JRC, Brockerman JA, Vuckovic M, Deng W, Okon M, Finlay BB, McIntosh LP, Strynadka NCJ.

Protein Sci. 2018 Aug 10. doi: 10.1002/pro.3447. [Epub ahead of print]

PMID:
30095200
2.

Structural Basis for Binding of Fluorescent CMP-Neu5Ac Mimetics to Enzymes of the Human ST8Sia Family.

Volkers G, Lizak C, Niesser J, Rosell FI, Preidl J, Gnanapragassam VS, Horstkorte R, Rademann J, Strynadka NCJ.

ACS Chem Biol. 2018 Jul 26. doi: 10.1021/acschembio.8b00478. [Epub ahead of print]

PMID:
30015474
3.

Structural and biochemical characterization of SpoIIIAF, a component of a sporulation-essential channel in Bacillus subtilis.

Zeytuni N, Flanagan KA, Worrall LJ, Massoni SC, Camp AH, Strynadka NCJ.

J Struct Biol. 2018 Jun 7. pii: S1047-8477(18)30140-0. doi: 10.1016/j.jsb.2018.06.002. [Epub ahead of print]

PMID:
29886194
4.

Enzyme structures of the bacterial peptidoglycan and wall teichoic acid biogenesis pathways.

Caveney NA, Li FK, Strynadka NC.

Curr Opin Struct Biol. 2018 Jun 6;53:45-58. doi: 10.1016/j.sbi.2018.05.002. [Epub ahead of print] Review.

PMID:
29885610
5.

IpdAB, a virulence factor in Mycobacterium tuberculosis, is a cholesterol ring-cleaving hydrolase.

Crowe AM, Workman SD, Watanabe N, Worrall LJ, Strynadka NCJ, Eltis LD.

Proc Natl Acad Sci U S A. 2018 Apr 10;115(15):E3378-E3387. doi: 10.1073/pnas.1717015115. Epub 2018 Mar 26.

PMID:
29581275
6.

Secretins revealed: structural insights into the giant gated outer membrane portals of bacteria.

Majewski DD, Worrall LJ, Strynadka NC.

Curr Opin Struct Biol. 2018 Mar 23;51:61-72. doi: 10.1016/j.sbi.2018.02.008. [Epub ahead of print] Review.

PMID:
29579693
7.

Crystal structure of an intramembranal phosphatase central to bacterial cell-wall peptidoglycan biosynthesis and lipid recycling.

Workman SD, Worrall LJ, Strynadka NCJ.

Nat Commun. 2018 Mar 20;9(1):1159. doi: 10.1038/s41467-018-03547-8.

8.

PBP4 activity and its overexpression are necessary for PBP4-mediated high-level β-lactam resistance.

Basuino L, Jousselin A, Alexander JAN, Strynadka NCJ, Pinho MG, Chambers HF, Chatterjee SS.

J Antimicrob Chemother. 2018 May 1;73(5):1177-1180. doi: 10.1093/jac/dkx531.

PMID:
29360990
9.

Structural characterization of SpoIIIAB sporulation-essential protein in Bacillus subtilis.

Zeytuni N, Flanagan KA, Worrall LJ, Massoni SC, Camp AH, Strynadka NCJ.

J Struct Biol. 2018 May;202(2):105-112. doi: 10.1016/j.jsb.2017.12.009. Epub 2017 Dec 26.

PMID:
29288127
10.

B. subtilis LytR-CpsA-Psr Enzymes Transfer Wall Teichoic Acids from Authentic Lipid-Linked Substrates to Mature Peptidoglycan In Vitro.

Gale RT, Li FKK, Sun T, Strynadka NCJ, Brown ED.

Cell Chem Biol. 2017 Dec 21;24(12):1537-1546.e4. doi: 10.1016/j.chembiol.2017.09.006. Epub 2017 Oct 26.

PMID:
29107701
11.

Near-atomic resolution cryoelectron microscopy structure of the 30-fold homooligomeric SpoIIIAG channel essential to spore formation in Bacillus subtilis.

Zeytuni N, Hong C, Flanagan KA, Worrall LJ, Theiltges KA, Vuckovic M, Huang RK, Massoni SC, Camp AH, Yu Z, Strynadka NC.

Proc Natl Acad Sci U S A. 2017 Aug 22;114(34):E7073-E7081. doi: 10.1073/pnas.1704310114. Epub 2017 Aug 7.

12.

X-ray crystallographic structure of a bacterial polysialyltransferase provides insight into the biosynthesis of capsular polysialic acid.

Lizak C, Worrall LJ, Baumann L, Pfleiderer MM, Volkers G, Sun T, Sim L, Wakarchuk W, Withers SG, Strynadka NCJ.

Sci Rep. 2017 Jul 19;7(1):5842. doi: 10.1038/s41598-017-05627-z.

13.

Corrigendum: Assembly, structure, function and regulation of type III secretion systems.

Deng W, Marshall NC, Rowland JL, McCoy JM, Worrall LJ, Santos AS, Strynadka NCJ, Finlay BB.

Nat Rev Microbiol. 2017 May 12;15(6):379. doi: 10.1038/nrmicro.2017.54. No abstract available.

PMID:
28496165
14.

Assembly, structure, function and regulation of type III secretion systems.

Deng W, Marshall NC, Rowland JL, McCoy JM, Worrall LJ, Santos AS, Strynadka NCJ, Finlay BB.

Nat Rev Microbiol. 2017 Jun;15(6):323-337. doi: 10.1038/nrmicro.2017.20. Epub 2017 Apr 10. Review. Erratum in: Nat Rev Microbiol. 2017 May 12;15(6):379.

PMID:
28392566
15.

High-Level Resistance of Staphylococcus aureus to β-Lactam Antibiotics Mediated by Penicillin-Binding Protein 4 (PBP4).

Hamilton SM, Alexander JAN, Choo EJ, Basuino L, da Costa TM, Severin A, Chung M, Aedo S, Strynadka NCJ, Tomasz A, Chatterjee SS, Chambers HF.

Antimicrob Agents Chemother. 2017 May 24;61(6). pii: e02727-16. doi: 10.1128/AAC.02727-16. Print 2017 Jun.

16.

Gentamicin B1 is a minor gentamicin component with major nonsense mutation suppression activity.

Baradaran-Heravi A, Niesser J, Balgi AD, Choi K, Zimmerman C, South AP, Anderson HJ, Strynadka NC, Bally MB, Roberge M.

Proc Natl Acad Sci U S A. 2017 Mar 28;114(13):3479-3484. doi: 10.1073/pnas.1620982114. Epub 2017 Mar 13.

17.

Near-atomic-resolution cryo-EM analysis of the Salmonella T3S injectisome basal body.

Worrall LJ, Hong C, Vuckovic M, Deng W, Bergeron JR, Majewski DD, Huang RK, Spreter T, Finlay BB, Yu Z, Strynadka NC.

Nature. 2016 Dec 14. doi: 10.1038/nature20576. [Epub ahead of print]

PMID:
27974800
18.

Structure and Mechanism of Staphylococcus aureus TarS, the Wall Teichoic Acid β-glycosyltransferase Involved in Methicillin Resistance.

Sobhanifar S, Worrall LJ, King DT, Wasney GA, Baumann L, Gale RT, Nosella M, Brown ED, Withers SG, Strynadka NC.

PLoS Pathog. 2016 Dec 14;12(12):e1006067. doi: 10.1371/journal.ppat.1006067. eCollection 2016 Dec.

19.

Structural Insights into Inhibition of Escherichia coli Penicillin-binding Protein 1B.

King DT, Wasney GA, Nosella M, Fong A, Strynadka NC.

J Biol Chem. 2017 Jan 20;292(3):979-993. doi: 10.1074/jbc.M116.718403. Epub 2016 Nov 29.

20.

Identification of Two Phosphate Starvation-induced Wall Teichoic Acid Hydrolases Provides First Insights into the Degradative Pathway of a Key Bacterial Cell Wall Component.

Myers CL, Li FK, Koo BM, El-Halfawy OM, French S, Gross CA, Strynadka NC, Brown ED.

J Biol Chem. 2016 Dec 9;291(50):26066-26082. Epub 2016 Oct 25.

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