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Items: 1 to 20 of 95

1.

The C-Terminal Transactivation Domain of STAT1 Has a Gene-Specific Role in Transactivation and Cofactor Recruitment.

Parrini M, Meissl K, Ola MJ, Lederer T, Puga A, Wienerroither S, Kovarik P, Decker T, Müller M, Strobl B.

Front Immunol. 2018 Dec 6;9:2879. doi: 10.3389/fimmu.2018.02879. eCollection 2018.

2.

Dependency on the TYK2/STAT1/MCL1 axis in anaplastic large cell lymphoma.

Prutsch N, Gurnhofer E, Suske T, Liang HC, Schlederer M, Roos S, Wu LC, Simonitsch-Klupp I, Alvarez-Hernandez A, Kornauth C, Leone DA, Svinka J, Eferl R, Limberger T, Aufinger A, Shirsath N, Wolf P, Hielscher T, Aberger F, Schmoellerl J, Stoiber D, Strobl B, Jäger U, Staber PB, Grebien F, Moriggl R, Müller M, Inghirami GG, Sanda T, Look AT, Turner SD, Kenner L, Merkel O.

Leukemia. 2018 Aug 21. doi: 10.1038/s41375-018-0239-1. [Epub ahead of print]

PMID:
30131584
3.

Aggressive B-cell lymphomas in patients with myelofibrosis receiving JAK1/2 inhibitor therapy.

Porpaczy E, Tripolt S, Hoelbl-Kovacic A, Gisslinger B, Bago-Horvath Z, Casanova-Hevia E, Clappier E, Decker T, Fajmann S, Fux DA, Greiner G, Gueltekin S, Heller G, Herkner H, Hoermann G, Kiladjian JJ, Kolbe T, Kornauth C, Krauth MT, Kralovics R, Muellauer L, Mueller M, Prchal-Murphy M, Putz EM, Raffoux E, Schiefer AI, Schmetterer K, Schneckenleithner C, Simonitsch-Klupp I, Skrabs C, Sperr WR, Staber PB, Strobl B, Valent P, Jaeger U, Gisslinger H, Sexl V.

Blood. 2018 Aug 16;132(7):694-706. doi: 10.1182/blood-2017-10-810739. Epub 2018 Jun 14.

PMID:
29907599
4.

STAT1 is a sex-specific tumor suppressor in colitis-associated colorectal cancer.

Crnčec I, Modak M, Gordziel C, Svinka J, Scharf I, Moritsch S, Pathria P, Schlederer M, Kenner L, Timelthaler G, Müller M, Strobl B, Casanova E, Bayer E, Mohr T, Stöckl J, Friedrich K, Eferl R.

Mol Oncol. 2018 Apr;12(4):514-528. doi: 10.1002/1878-0261.12178. Epub 2018 Feb 20.

5.

Kinase Inactive Tyrosine Kinase (Tyk2) Supports Differentiation of Brown Fat Cells.

Raje V, Derecka M, Cantwell M, Meier J, Szczepanek K, Sisler JD, Strobl B, Gamero A, Harris TE, Larner AC.

Endocrinology. 2017 Jan 1;158(1):148-157. doi: 10.1210/en.2015-2048.

6.

Type I interferon promotes alveolar epithelial type II cell survival during pulmonary Streptococcus pneumoniae infection and sterile lung injury in mice.

Maier BB, Hladik A, Lakovits K, Korosec A, Martins R, Kral JB, Mesteri I, Strobl B, Müller M, Kalinke U, Merad M, Knapp S.

Eur J Immunol. 2016 Sep;46(9):2175-86. doi: 10.1002/eji.201546201. Epub 2016 Jul 12.

7.

Defining the functional binding sites of interleukin 12 receptor β1 and interleukin 23 receptor to Janus kinases.

Floss DM, Klöcker T, Schröder J, Lamertz L, Mrotzek S, Strobl B, Hermanns H, Scheller J.

Mol Biol Cell. 2016 Jul 15;27(14):2301-16. doi: 10.1091/mbc.E14-12-1645. Epub 2016 May 18.

8.

Type I Interferon Signaling Prevents IL-1β-Driven Lethal Systemic Hyperinflammation during Invasive Bacterial Infection of Soft Tissue.

Castiglia V, Piersigilli A, Ebner F, Janos M, Goldmann O, Damböck U, Kröger A, Weiss S, Knapp S, Jamieson AM, Kirschning C, Kalinke U, Strobl B, Müller M, Stoiber D, Lienenklaus S, Kovarik P.

Cell Host Microbe. 2016 Mar 9;19(3):375-87. doi: 10.1016/j.chom.2016.02.003.

9.

STAT5 Is a Key Regulator in NK Cells and Acts as a Molecular Switch from Tumor Surveillance to Tumor Promotion.

Gotthardt D, Putz EM, Grundschober E, Prchal-Murphy M, Straka E, Kudweis P, Heller G, Bago-Horvath Z, Witalisz-Siepracka A, Cumaraswamy AA, Gunning PT, Strobl B, Müller M, Moriggl R, Stockmann C, Sexl V.

Cancer Discov. 2016 Apr;6(4):414-29. doi: 10.1158/2159-8290.CD-15-0732. Epub 2016 Feb 12.

10.

Intestinal Microbiota Signatures Associated with Inflammation History in Mice Experiencing Recurring Colitis.

Berry D, Kuzyk O, Rauch I, Heider S, Schwab C, Hainzl E, Decker T, Müller M, Strobl B, Schleper C, Urich T, Wagner M, Kenner L, Loy A.

Front Microbiol. 2015 Dec 15;6:1408. doi: 10.3389/fmicb.2015.01408. eCollection 2015.

11.

The good and the bad faces of STAT1 in solid tumours.

Meissl K, Macho-Maschler S, Müller M, Strobl B.

Cytokine. 2017 Jan;89:12-20. doi: 10.1016/j.cyto.2015.11.011. Epub 2015 Nov 26. Review.

12.

Tyrosine kinase 2 - Surveillant of tumours and bona fide oncogene.

Leitner NR, Witalisz-Siepracka A, Strobl B, Müller M.

Cytokine. 2017 Jan;89:209-218. doi: 10.1016/j.cyto.2015.10.015. Epub 2015 Nov 26. Review.

13.

In vivo tumor surveillance by NK cells requires TYK2 but not TYK2 kinase activity.

Prchal-Murphy M, Witalisz-Siepracka A, Bednarik KT, Putz EM, Gotthardt D, Meissl K, Sexl V, Müller M, Strobl B.

Oncoimmunology. 2015 May 26;4(11):e1047579. eCollection 2015 Nov.

14.

Intestinal Epithelial Cell Tyrosine Kinase 2 Transduces IL-22 Signals To Protect from Acute Colitis.

Hainzl E, Stockinger S, Rauch I, Heider S, Berry D, Lassnig C, Schwab C, Rosebrock F, Milinovich G, Schlederer M, Wagner M, Schleper C, Loy A, Urich T, Kenner L, Han X, Decker T, Strobl B, Müller M.

J Immunol. 2015 Nov 15;195(10):5011-24. doi: 10.4049/jimmunol.1402565. Epub 2015 Oct 2.

15.

Cooperative Transcriptional Activation of Antimicrobial Genes by STAT and NF-κB Pathways by Concerted Recruitment of the Mediator Complex.

Wienerroither S, Shukla P, Farlik M, Majoros A, Stych B, Vogl C, Cheon H, Stark GR, Strobl B, Müller M, Decker T.

Cell Rep. 2015 Jul 14;12(2):300-12. doi: 10.1016/j.celrep.2015.06.021. Epub 2015 Jul 2.

16.

Myeloid STAT3 promotes formation of colitis-associated colorectal cancer in mice.

Pathria P, Gotthardt D, Prchal-Murphy M, Putz EM, Holcmann M, Schlederer M, Grabner B, Crncec I, Svinka J, Musteanu M, Hoffmann T, Filipits M, Berger W, Poli V, Kenner L, Bilban M, Casanova E, Müller M, Strobl B, Bayer E, Mohr T, Sexl V, Eferl R.

Oncoimmunology. 2015 Jan 22;4(4):e998529. eCollection 2015 Apr.

17.

Noncanonical Effects of IRF9 in Intestinal Inflammation: More than Type I and Type III Interferons.

Rauch I, Rosebrock F, Hainzl E, Heider S, Majoros A, Wienerroither S, Strobl B, Stockinger S, Kenner L, Müller M, Decker T.

Mol Cell Biol. 2015 Jul;35(13):2332-43. doi: 10.1128/MCB.01498-14. Epub 2015 Apr 27.

18.

Methods to study tumor surveillance using tumor cell transplantation into genetically engineered mice.

Bauer E, Witalisz A, Strobl B, Stoiber D.

Methods Mol Biol. 2015;1267:439-56. doi: 10.1007/978-1-4939-2297-0_22.

PMID:
25636483
19.

Promoter occupancy of STAT1 in interferon responses is regulated by processive transcription.

Wiesauer I, Gaumannmüller C, Steinparzer I, Strobl B, Kovarik P.

Mol Cell Biol. 2015 Feb;35(4):716-27. doi: 10.1128/MCB.01097-14. Epub 2014 Dec 15.

20.

Interruption of macrophage-derived IL-27(p28) production by IL-10 during sepsis requires STAT3 but not SOCS3.

Bosmann M, Russkamp NF, Strobl B, Roewe J, Balouzian L, Pache F, Radsak MP, van Rooijen N, Zetoune FS, Sarma JV, Núñez G, Müller M, Murray PJ, Ward PA.

J Immunol. 2014 Dec 1;193(11):5668-77. doi: 10.4049/jimmunol.1302280. Epub 2014 Oct 27.

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