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Items: 1 to 20 of 44


C/EBPδ links IL-6 and HIF-1 signaling to promote breast cancer stem cell-associated phenotypes.

Balamurugan K, Mendoza-Villanueva D, Sharan S, Summers GH, Dobrolecki LE, Lewis MT, Sterneck E.

Oncogene. 2018 Sep 27. doi: 10.1038/s41388-018-0516-5. [Epub ahead of print]


Scientific Summary from the Morgan Welch MD Anderson Cancer Center Inflammatory Breast Cancer (IBC) Program 10th Anniversary Conference.

Woodward WA, Cristofanilli M, Merajver SD, Van Laere S, Pusztai L, Bertucci F, Berditchevski F, Polyak K, Overmoyer B, Devi GR, Sterneck E, Schneider R, Debeb BG, Wang X, van Golen KL, El-Zein R, Rahal OM, Alexander A, Reuben JM, Krishnamurthy S, Lucci A, Ueno NT.

J Cancer. 2017 Oct 9;8(17):3607-3614. doi: 10.7150/jca.21200. eCollection 2017.


The C/EBPδ protein is stabilized by estrogen receptor α activity, inhibits SNAI2 expression and associates with good prognosis in breast cancer.

Mendoza-Villanueva D, Balamurugan K, Ali HR, Kim SR, Sharan S, Johnson RC, Merchant AS, Caldas C, Landberg G, Sterneck E.

Oncogene. 2016 Dec 1;35(48):6166-6176. doi: 10.1038/onc.2016.156. Epub 2016 May 16.


C/EBPδ deficiency sensitizes mice to ionizing radiation-induced hematopoietic and intestinal injury.

Pawar SA, Shao L, Chang J, Wang W, Pathak R, Zhu X, Wang J, Hendrickson H, Boerma M, Sterneck E, Zhou D, Hauer-Jensen M.

PLoS One. 2014 Apr 18;9(4):e94967. doi: 10.1371/journal.pone.0094967. eCollection 2014.


The many faces of C/EBPδ and their relevance for inflammation and cancer.

Balamurugan K, Sterneck E.

Int J Biol Sci. 2013 Sep 20;9(9):917-33. doi: 10.7150/ijbs.7224. eCollection 2013. Review.


Positional variations in mammary gland development and cancer.

Veltmaat JM, Ramsdell AF, Sterneck E.

J Mammary Gland Biol Neoplasia. 2013 Jun;18(2):179-88. doi: 10.1007/s10911-013-9287-3. Epub 2013 May 12. Review.


FBXW7α attenuates inflammatory signalling by downregulating C/EBPδ and its target gene Tlr4.

Balamurugan K, Sharan S, Klarmann KD, Zhang Y, Coppola V, Summers GH, Roger T, Morrison DK, Keller JR, Sterneck E.

Nat Commun. 2013;4:1662. doi: 10.1038/ncomms2677.


Identification of a Src tyrosine kinase/SIAH2 E3 ubiquitin ligase pathway that regulates C/EBPδ expression and contributes to transformation of breast tumor cells.

Sarkar TR, Sharan S, Wang J, Pawar SA, Cantwell CA, Johnson PF, Morrison DK, Wang JM, Sterneck E.

Mol Cell Biol. 2012 Jan;32(2):320-32. doi: 10.1128/MCB.05790-11. Epub 2011 Oct 28.


CCAAT/enhancer binding protein delta (CEBPD) elevating PTX3 expression inhibits macrophage-mediated phagocytosis of dying neuron cells.

Ko CY, Chang LH, Lee YC, Sterneck E, Cheng CP, Chen SH, Huang AM, Tseng JT, Wang JM.

Neurobiol Aging. 2012 Feb;33(2):422.e11-25. doi: 10.1016/j.neurobiolaging.2010.09.017. Epub 2010 Nov 26.


The tumour suppressor C/EBPδ inhibits FBXW7 expression and promotes mammary tumour metastasis.

Balamurugan K, Wang JM, Tsai HH, Sharan S, Anver M, Leighty R, Sterneck E.

EMBO J. 2010 Dec 15;29(24):4106-17. doi: 10.1038/emboj.2010.280. Epub 2010 Nov 12.


CEBPD reverses RB/E2F1-mediated gene repression and participates in HMDB-induced apoptosis of cancer cells.

Pan YC, Li CF, Ko CY, Pan MH, Chen PJ, Tseng JT, Wu WC, Chang WC, Huang AM, Sterneck E, Wang JM.

Clin Cancer Res. 2010 Dec 1;16(23):5770-80. doi: 10.1158/1078-0432.CCR-10-1025. Epub 2010 Oct 22.


CCAAT/enhancer binding protein delta (C/EBPdelta, CEBPD)-mediated nuclear import of FANCD2 by IPO4 augments cellular response to DNA damage.

Wang J, Sarkar TR, Zhou M, Sharan S, Ritt DA, Veenstra TD, Morrison DK, Huang AM, Sterneck E.

Proc Natl Acad Sci U S A. 2010 Sep 14;107(37):16131-6. doi: 10.1073/pnas.1002603107. Epub 2010 Aug 30.


C/EBP{delta} targets cyclin D1 for proteasome-mediated degradation via induction of CDC27/APC3 expression.

Pawar SA, Sarkar TR, Balamurugan K, Sharan S, Wang J, Zhang Y, Dowdy SF, Huang AM, Sterneck E.

Proc Natl Acad Sci U S A. 2010 May 18;107(20):9210-5. doi: 10.1073/pnas.0913813107. Epub 2010 May 3.


Transcriptional up-regulation of SOD1 by CEBPD: a potential target for cisplatin resistant human urothelial carcinoma cells.

Hour TC, Lai YL, Kuan CI, Chou CK, Wang JM, Tu HY, Hu HT, Lin CS, Wu WJ, Pu YS, Sterneck E, Huang AM.

Biochem Pharmacol. 2010 Aug 1;80(3):325-34. doi: 10.1016/j.bcp.2010.04.007. Epub 2010 Apr 10.


MAPK3/1 (ERK1/2) in ovarian granulosa cells are essential for female fertility.

Fan HY, Liu Z, Shimada M, Sterneck E, Johnson PF, Hedrick SM, Richards JS.

Science. 2009 May 15;324(5929):938-41. doi: 10.1126/science.1171396.


Transcription factor C/EBPbeta isoform ratio regulates osteoclastogenesis through MafB.

Smink JJ, Bégay V, Schoenmaker T, Sterneck E, de Vries TJ, Leutz A.

EMBO J. 2009 Jun 17;28(12):1769-81. doi: 10.1038/emboj.2009.127. Epub 2009 May 14.


CAATT/enhancer-binding proteins alpha and delta interact with NKX2-1 to synergistically activate mouse secretoglobin 3A2 gene expression.

Tomita T, Kido T, Kurotani R, Iemura S, Sterneck E, Natsume T, Vinson C, Kimura S.

J Biol Chem. 2008 Sep 12;283(37):25617-27. doi: 10.1074/jbc.M805140200. Epub 2008 Jul 16.


The Cebpd (C/EBPdelta) gene is induced by luteinizing hormones in ovarian theca and interstitial cells but is not essential for mouse ovary function.

Huang AM, Rudelius M, Sharan S, McAllister JM, Raffeld M, Christenson LK, Sterneck E.

PLoS One. 2007 Dec 19;2(12):e1334.


SLC5A8 triggers tumor cell apoptosis through pyruvate-dependent inhibition of histone deacetylases.

Thangaraju M, Gopal E, Martin PM, Ananth S, Smith SB, Prasad PD, Sterneck E, Ganapathy V.

Cancer Res. 2006 Dec 15;66(24):11560-4.


c/ebpdelta Null mouse as a model for the double knock-out of slc5a8 and slc5a12 in kidney.

Thangaraju M, Ananth S, Martin PM, Roon P, Smith SB, Sterneck E, Prasad PD, Ganapathy V.

J Biol Chem. 2006 Sep 15;281(37):26769-73. Epub 2006 Jul 26.

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