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Items: 1 to 20 of 44


Alterations in neuronal metabolism contribute to the pathogenesis of prion disease.

Bourgognon JM, Spiers JG, Scheiblich H, Antonov A, Bradley SJ, Tobin AB, Steinert JR.

Cell Death Differ. 2018 Aug;25(8):1408-1425. doi: 10.1038/s41418-018-0148-x. Epub 2018 Jun 18.


Nitric oxide-mediated posttranslational modifications control neurotransmitter release by modulating complexin farnesylation and enhancing its clamping ability.

Robinson SW, Bourgognon JM, Spiers JG, Breda C, Campesan S, Butcher A, Mallucci GR, Dinsdale D, Morone N, Mistry R, Smith TM, Guerra-Martin M, Challiss RAJ, Giorgini F, Steinert JR.

PLoS Biol. 2018 Apr 9;16(4):e2003611. doi: 10.1371/journal.pbio.2003611. eCollection 2018 Apr.


Myostatin-like proteins regulate synaptic function and neuronal morphology.

Augustin H, McGourty K, Steinert JR, Cochemé HM, Adcott J, Cabecinha M, Vincent A, Halff EF, Kittler JT, Boucrot E, Partridge L.

Development. 2017 Jul 1;144(13):2445-2455. doi: 10.1242/dev.152975. Epub 2017 May 22.


Activated inhibition in regulating excitability.

Steinert JR.

J Physiol. 2017 Jun 1;595(11):3243-3244. doi: 10.1113/JP274196. Epub 2017 Apr 11. No abstract available.


M1 muscarinic allosteric modulators slow prion neurodegeneration and restore memory loss.

Bradley SJ, Bourgognon JM, Sanger HE, Verity N, Mogg AJ, White DJ, Butcher AJ, Moreno JA, Molloy C, Macedo-Hatch T, Edwards JM, Wess J, Pawlak R, Read DJ, Sexton PM, Broad LM, Steinert JR, Mallucci GR, Christopoulos A, Felder CC, Tobin AB.

J Clin Invest. 2017 Feb 1;127(2):487-499. doi: 10.1172/JCI87526. Epub 2016 Dec 19.


The Amino Acid Transporter JhI-21 Coevolves with Glutamate Receptors, Impacts NMJ Physiology, and Influences Locomotor Activity in Drosophila Larvae.

Ziegler AB, Augustin H, Clark NL, Berthelot-Grosjean M, Simonnet MM, Steinert JR, Geillon F, Manière G, Featherstone DE, Grosjean Y.

Sci Rep. 2016 Jan 25;6:19692. doi: 10.1038/srep19692.


Nitric Oxide: A Regulator of Cellular Function in Health and Disease.

Sobrevia L, Ooi L, Ryan S, Steinert JR.

Oxid Med Cell Longev. 2016;2016:9782346. doi: 10.1155/2016/9782346. Epub 2015 Dec 21. No abstract available.


Nitric Oxide-Mediated Posttranslational Modifications: Impacts at the Synapse.

Bradley SA, Steinert JR.

Oxid Med Cell Longev. 2016;2016:5681036. doi: 10.1155/2016/5681036. Epub 2015 Nov 9. Review.


Prion protein as a mediator of synaptic transmission.

Steinert JR.

Commun Integr Biol. 2015 Aug 14;8(4):e1063753. doi: 10.1080/19420889.2015.1063753. eCollection 2015 Jul-Aug.


Characterisation and comparison of temporal release profiles of nitric oxide generating donors.

Bradley SA, Steinert JR.

J Neurosci Methods. 2015 Apr 30;245:116-24. doi: 10.1016/j.jneumeth.2015.02.024. Epub 2015 Mar 6.


RBM3 mediates structural plasticity and protective effects of cooling in neurodegeneration.

Peretti D, Bastide A, Radford H, Verity N, Molloy C, Martin MG, Moreno JA, Steinert JR, Smith T, Dinsdale D, Willis AE, Mallucci GR.

Nature. 2015 Feb 12;518(7538):236-9. doi: 10.1038/nature14142. Epub 2015 Jan 14.


Rab11 modulates α-synuclein-mediated defects in synaptic transmission and behaviour.

Breda C, Nugent ML, Estranero JG, Kyriacou CP, Outeiro TF, Steinert JR, Giorgini F.

Hum Mol Genet. 2015 Feb 15;24(4):1077-91. doi: 10.1093/hmg/ddu521. Epub 2014 Oct 9.


Prion protein facilitates synaptic vesicle release by enhancing release probability.

Robinson SW, Nugent ML, Dinsdale D, Steinert JR.

Hum Mol Genet. 2014 Sep 1;23(17):4581-96. doi: 10.1093/hmg/ddu171. Epub 2014 Apr 9.


Rab11 as a modulator of synaptic transmission.

Giorgini F, Steinert JR.

Commun Integr Biol. 2013 Nov 1;6(6):e26807. doi: 10.4161/cib.26807. Epub 2013 Nov 13.


TAp73 knockout mice show morphological and functional nervous system defects associated with loss of p75 neurotrophin receptor.

Niklison-Chirou MV, Steinert JR, Agostini M, Knight RA, Dinsdale D, Cattaneo A, Mak TW, Melino G.

Proc Natl Acad Sci U S A. 2013 Nov 19;110(47):18952-7. doi: 10.1073/pnas.1221172110. Epub 2013 Nov 4.


Protection from noise-induced hearing loss by Kv2.2 potassium currents in the central medial olivocochlear system.

Tong H, Kopp-Scheinpflug C, Pilati N, Robinson SW, Sinclair JL, Steinert JR, Barnes-Davies M, Allfree R, Grubb BD, Young SM Jr, Forsythe ID.

J Neurosci. 2013 May 22;33(21):9113-21. doi: 10.1523/JNEUROSCI.5043-12.2013.


A gas that ignites a bright spark.

Steinert JR.

J Physiol. 2012 Jul 15;590(14):3213-4. doi: 10.1113/jphysiol.2012.235556. No abstract available.


Sustained translational repression by eIF2α-P mediates prion neurodegeneration.

Moreno JA, Radford H, Peretti D, Steinert JR, Verity N, Martin MG, Halliday M, Morgan J, Dinsdale D, Ortori CA, Barrett DA, Tsaytler P, Bertolotti A, Willis AE, Bushell M, Mallucci GR.

Nature. 2012 May 6;485(7399):507-11. doi: 10.1038/nature11058. Erratum in: Nature.2014 Jul 17;511(7509):370.


Rab11 rescues synaptic dysfunction and behavioural deficits in a Drosophila model of Huntington's disease.

Steinert JR, Campesan S, Richards P, Kyriacou CP, Forsythe ID, Giorgini F.

Hum Mol Genet. 2012 Jul 1;21(13):2912-22. doi: 10.1093/hmg/dds117. Epub 2012 Mar 30.


Nitric oxide signalling augments neuronal voltage-gated L-type (Ca(v)1) and P/q-type (Ca(v)2.1) channels in the mouse medial nucleus of the trapezoid body.

Tozer AJ, Forsythe ID, Steinert JR.

PLoS One. 2012;7(2):e32256. doi: 10.1371/journal.pone.0032256. Epub 2012 Feb 28.

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