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Single Muscle Fiber Proteomics Reveals Distinct Protein Changes in Slow and Fast Fibers during Muscle Atrophy.

Lang F, Khaghani S, Türk C, Wiederstein JL, Hölper S, Piller T, Nogara L, Blaauw B, Günther S, Müller S, Braun T, Krüger M.

J Proteome Res. 2018 Sep 5. doi: 10.1021/acs.jproteome.8b00093. [Epub ahead of print]


New insights into the structural dynamics of the kinase JNK3.

Mishra P, Günther S.

Sci Rep. 2018 Jun 21;8(1):9435. doi: 10.1038/s41598-018-27867-3.


MiCEE is a ncRNA-protein complex that mediates epigenetic silencing and nucleolar organization.

Singh I, Contreras A, Cordero J, Rubio K, Dobersch S, Günther S, Jeratsch S, Mehta A, Krüger M, Graumann J, Seeger W, Dobreva G, Braun T, Barreto G.

Nat Genet. 2018 Jul;50(7):990-1001. doi: 10.1038/s41588-018-0139-3. Epub 2018 Jun 4.


Reg proteins direct accumulation of functionally distinct macrophage subsets after myocardial infarction.

Lörchner H, Hou Y, Adrian-Segarra JM, Kulhei J, Detzer J, Günther S, Gajawada P, Warnecke H, Niessen HW, Pöling J, Braun T.

Cardiovasc Res. 2018 Oct 1;114(12):1667-1679. doi: 10.1093/cvr/cvy126.


The Hippo pathway effector Wwtr1 regulates cardiac wall maturation in zebrafish.

Lai JKH, Collins MM, Uribe V, Jiménez-Amilburu V, Günther S, Maischein HM, Stainier DYR.

Development. 2018 May 17;145(10). pii: dev159210. doi: 10.1242/dev.159210.


Skeletal Muscle-Specific Methyltransferase METTL21C Trimethylates p97 and Regulates Autophagy-Associated Protein Breakdown.

Wiederstein JL, Nolte H, Günther S, Piller T, Baraldo M, Kostin S, Bloch W, Schindler N, Sandri M, Blaauw B, Braun T, Hölper S, Krüger M.

Cell Rep. 2018 May 1;23(5):1342-1356. doi: 10.1016/j.celrep.2018.03.136.


Metabolic Maturation during Muscle Stem Cell Differentiation Is Achieved by miR-1/133a-Mediated Inhibition of the Dlk1-Dio3 Mega Gene Cluster.

Wüst S, Dröse S, Heidler J, Wittig I, Klockner I, Franko A, Bonke E, Günther S, Gärtner U, Boettger T, Braun T.

Cell Metab. 2018 May 1;27(5):1026-1039.e6. doi: 10.1016/j.cmet.2018.02.022. Epub 2018 Apr 5.


Switch in Laminin β2 to Laminin β1 Isoforms During Aging Controls Endothelial Cell Functions-Brief Report.

Wagner JUG, Chavakis E, Rogg EM, Muhly-Reinholz M, Glaser SF, Günther S, John D, Bonini F, Zeiher AM, Schaefer L, Hannocks MJ, Boon RA, Dimmeler S.

Arterioscler Thromb Vasc Biol. 2018 May;38(5):1170-1177. doi: 10.1161/ATVBAHA.117.310685. Epub 2018 Mar 29.


Gene expression profiling of human bronchial epithelial cells exposed to fine particulate matter (PM2.5) from biomass combustion.

Popadić D, Heßelbach K, Richter-Brockmann S, Kim GJ, Flemming S, Schmidt-Heck W, Häupl T, Bonin M, Dornhof R, Achten C, Günther S, Humar M, Merfort I.

Toxicol Appl Pharmacol. 2018 May 15;347:10-22. doi: 10.1016/j.taap.2018.03.024. Epub 2018 Mar 26. No abstract available.


Transmission of microRNA antimiRs to mouse offspring via the maternal-placental-fetal unit.

Hönig J, Mižíková I, Nardiello C, Surate Solaligue DE, Daume MJ, Vadász I, Mayer K, Herold S, Günther S, Seeger W, Morty RE.

RNA. 2018 Jun;24(6):865-879. doi: 10.1261/rna.063206.117. Epub 2018 Mar 14.


Clonal Expansion of Endothelial Cells Contributes to Ischemia-Induced Neovascularization.

Manavski Y, Lucas T, Glaser SF, Dorsheimer L, Günther S, Braun T, Rieger MA, Zeiher AM, Boon RA, Dimmeler S.

Circ Res. 2018 Mar 2;122(5):670-677. doi: 10.1161/CIRCRESAHA.117.312310. Epub 2018 Jan 22.


Members of Bitter Taste Receptor Cluster Tas2r143/Tas2r135/Tas2r126 Are Expressed in the Epithelium of Murine Airways and Other Non-gustatory Tissues.

Liu S, Lu S, Xu R, Atzberger A, Günther S, Wettschureck N, Offermanns S.

Front Physiol. 2017 Oct 30;8:849. doi: 10.3389/fphys.2017.00849. eCollection 2017.


Small RNA Sequencing Reveals Dlk1-Dio3 Locus-Embedded MicroRNAs as Major Drivers of Ground-State Pluripotency.

Moradi S, Sharifi-Zarchi A, Ahmadi A, Mollamohammadi S, Stubenvoll A, Günther S, Salekdeh GH, Asgari S, Braun T, Baharvand H.

Stem Cell Reports. 2017 Dec 12;9(6):2081-2096. doi: 10.1016/j.stemcr.2017.10.009. Epub 2017 Nov 9.


In vitro observations and in silico predictions of xenoestrogen mixture effects in T47D-based receptor transactivation and proliferation assays.

Schlotz N, Kim GJ, Jäger S, Günther S, Lamy E.

Toxicol In Vitro. 2017 Dec;45(Pt 1):146-157. doi: 10.1016/j.tiv.2017.08.017. Epub 2017 Aug 30.


Single-cell profiling reveals GPCR heterogeneity and functional patterning during neuroinflammation.

Tischner D, Grimm M, Kaur H, Staudenraus D, Carvalho J, Looso M, Günther S, Wanke F, Moos S, Siller N, Breuer J, Schwab N, Zipp F, Waisman A, Kurschus FC, Offermanns S, Wettschureck N.

JCI Insight. 2017 Aug 3;2(15). pii: 95063. doi: 10.1172/jci.insight.95063. [Epub ahead of print]


Beyond the BET Family: Targeting CBP/p300 with 4-Acyl Pyrroles.

Hügle M, Lucas X, Ostrovskyi D, Regenass P, Gerhardt S, Einsle O, Hau M, Jung M, Breit B, Günther S, Wohlwend D.

Angew Chem Int Ed Engl. 2017 Oct 2;56(41):12476-12480. doi: 10.1002/anie.201705516. Epub 2017 Sep 7.


Disease relevant modifications of the methylome and transcriptome by particulate matter (PM2.5) from biomass combustion.

Heßelbach K, Kim GJ, Flemming S, Häupl T, Bonin M, Dornhof R, Günther S, Merfort I, Humar M.

Epigenetics. 2017 Sep;12(9):779-792. doi: 10.1080/15592294.2017.1356555. Epub 2017 Oct 27.


NANPDB: A Resource for Natural Products from Northern African Sources.

Ntie-Kang F, Telukunta KK, Döring K, Simoben CV, A Moumbock AF, Malange YI, Njume LE, Yong JN, Sippl W, Günther S.

J Nat Prod. 2017 Jul 28;80(7):2067-2076. doi: 10.1021/acs.jnatprod.7b00283. Epub 2017 Jun 22.


Dynamic changes in the mouse skeletal muscle proteome during denervation-induced atrophy.

Lang F, Aravamudhan S, Nolte H, Türk C, Hölper S, Müller S, Günther S, Blaauw B, Braun T, Krüger M.

Dis Model Mech. 2017 Jul 1;10(7):881-896. doi: 10.1242/dmm.028910. Epub 2017 May 25.


SeMPI: a genome-based secondary metabolite prediction and identification web server.

Zierep PF, Padilla N, Yonchev DG, Telukunta KK, Klementz D, Günther S.

Nucleic Acids Res. 2017 Jul 3;45(W1):W64-W71. doi: 10.1093/nar/gkx289.

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