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Items: 1 to 20 of 95


Concise, Simple, and Not Wrong: In Search of a Short-Hand Interpretation of Statistical Significance.

Spence JR, Stanley DJ.

Front Psychol. 2018 Nov 13;9:2185. doi: 10.3389/fpsyg.2018.02185. eCollection 2018.


Natural succession and clearcutting as drivers of environmental heterogeneity and beta diversity in North American boreal forests.

García-Tejero S, Spence JR, O'Halloran J, Bourassa S, Oxbrough A.

PLoS One. 2018 Nov 2;13(11):e0206931. doi: 10.1371/journal.pone.0206931. eCollection 2018.


Publisher Correction: PEG-4MAL hydrogels for human organoid generation, culture, and in vivo delivery.

Cruz-Acuña R, Quirós M, Huang S, Siuda D, Spence JR, Nusrat A, García AJ.

Nat Protoc. 2018 Oct 24. doi: 10.1038/s41596-018-0079-5. [Epub ahead of print]


PEG-4MAL hydrogels for human organoid generation, culture, and in vivo delivery.

Cruz-Acuña R, Quirós M, Huang S, Siuda D, Spence JR, Nusrat A, García AJ.

Nat Protoc. 2018 Sep;13(9):2102-2119. doi: 10.1038/s41596-018-0036-3. Erratum in: Nat Protoc. 2018 Oct 24;:.


Single-cell analysis of progenitor cell dynamics and lineage specification in the human fetal kidney.

Menon R, Otto EA, Kokoruda A, Zhou J, Zhang Z, Yoon E, Chen YC, Troyanskaya O, Spence JR, Kretzler M, Cebrián C.

Development. 2018 Aug 30;145(16). pii: dev164038. doi: 10.1242/dev.164038.


A Method for Cryogenic Preservation of Human Biopsy Specimens and Subsequent Organoid Culture.

Tsai YH, Czerwinski M, Wu A, Dame MK, Attili D, Hill E, Colacino JA, Nowacki LM, Shroyer NF, Higgins PDR, Kao JY, Spence JR.

Cell Mol Gastroenterol Hepatol. 2018 May 30;6(2):218-222.e7. doi: 10.1016/j.jcmgh.2018.04.008. eCollection 2018. No abstract available.


Lactobacillus rhamnosus GG prevents epithelial barrier dysfunction induced by interferon-gamma and fecal supernatants from irritable bowel syndrome patients in human intestinal enteroids and colonoids.

Han X, Lee A, Huang S, Gao J, Spence JR, Owyang C.

Gut Microbes. 2018 Jul 24:1-18. doi: 10.1080/19490976.2018.1479625. [Epub ahead of print]


Taming the Wild West of Organoids, Enteroids, and Mini-Guts.

Spence JR.

Cell Mol Gastroenterol Hepatol. 2017 Nov 28;5(2):159-160. doi: 10.1016/j.jcmgh.2017.11.003. eCollection 2018. No abstract available.


Identification, isolation and characterization of human LGR5-positive colon adenoma cells.

Dame MK, Attili D, McClintock SD, Dedhia PH, Ouillette P, Hardt O, Chin AM, Xue X, Laliberte J, Katz EL, Newsome GM, Hill DR, Miller AJ, Tsai YH, Agorku D, Altheim CH, Bosio A, Simon B, Samuelson LC, Stoerker JA, Appelman HD, Varani J, Wicha MS, Brenner DE, Shah YM, Spence JR, Colacino JA.

Development. 2018 Mar 14;145(6). pii: dev153049. doi: 10.1242/dev.153049.


Real-time Measurement of Epithelial Barrier Permeability in Human Intestinal Organoids.

Hill DR, Huang S, Tsai YH, Spence JR, Young VB.

J Vis Exp. 2017 Dec 18;(130). doi: 10.3791/56960.


Species traits modify the species-area relationship in ground-beetle (Coleoptera: Carabidae) assemblages on islands in a boreal lake.

Bell AJ, Phillips ID, Nielsen SE, Spence JR.

PLoS One. 2017 Dec 20;12(12):e0190174. doi: 10.1371/journal.pone.0190174. eCollection 2017.


In Vitro Induction and In Vivo Engraftment of Lung Bud Tip Progenitor Cells Derived from Human Pluripotent Stem Cells.

Miller AJ, Hill DR, Nagy MS, Aoki Y, Dye BR, Chin AM, Huang S, Zhu F, White ES, Lama V, Spence JR.

Stem Cell Reports. 2018 Jan 9;10(1):101-119. doi: 10.1016/j.stemcr.2017.11.012. Epub 2017 Dec 14.


Clocking the Pace of Organoid Research.

Spence JR.

Cell Mol Gastroenterol Hepatol. 2017 May 13;4(1):203-204. doi: 10.1016/j.jcmgh.2017.04.006. eCollection 2017 Jul. No abstract available.


Bacterial colonization stimulates a complex physiological response in the immature human intestinal epithelium.

Hill DR, Huang S, Nagy MS, Yadagiri VK, Fields C, Mukherjee D, Bons B, Dedhia PH, Chin AM, Tsai YH, Thodla S, Schmidt TM, Walk S, Young VB, Spence JR.

Elife. 2017 Nov 7;6. pii: e29132. doi: 10.7554/eLife.29132.


Quantitative proteomics identifies STEAP4 as a critical regulator of mitochondrial dysfunction linking inflammation and colon cancer.

Xue X, Bredell BX, Anderson ER, Martin A, Mays C, Nagao-Kitamoto H, Huang S, Győrffy B, Greenson JK, Hardiman K, Spence JR, Kamada N, Shah YM.

Proc Natl Acad Sci U S A. 2017 Nov 7;114(45):E9608-E9617. doi: 10.1073/pnas.1712946114. Epub 2017 Oct 23.


Synthetic hydrogels for human intestinal organoid generation and colonic wound repair.

Cruz-Acuña R, Quirós M, Farkas AE, Dedhia PH, Huang S, Siuda D, García-Hernández V, Miller AJ, Spence JR, Nusrat A, García AJ.

Nat Cell Biol. 2017 Nov;19(11):1326-1335. doi: 10.1038/ncb3632. Epub 2017 Oct 23.


Neural Crest Cell Implantation Restores Enteric Nervous System Function and Alters the Gastrointestinal Transcriptome in Human Tissue-Engineered Small Intestine.

Schlieve CR, Fowler KL, Thornton M, Huang S, Hajjali I, Hou X, Grubbs B, Spence JR, Grikscheit TC.

Stem Cell Reports. 2017 Sep 12;9(3):883-896. doi: 10.1016/j.stemcr.2017.07.017. Epub 2017 Aug 10.


Differentiation of Human Pluripotent Stem Cells into Colonic Organoids via Transient Activation of BMP Signaling.

Múnera JO, Sundaram N, Rankin SA, Hill D, Watson C, Mahe M, Vallance JE, Shroyer NF, Sinagoga KL, Zarzoso-Lacoste A, Hudson JR, Howell JC, Chatuvedi P, Spence JR, Shannon JM, Zorn AM, Helmrath MA, Wells JM.

Cell Stem Cell. 2017 Jul 6;21(1):51-64.e6. doi: 10.1016/j.stem.2017.05.020. Epub 2017 Jun 22.


Bioengineering for intestinal organoid cultures.

Kim GA, Spence JR, Takayama S.

Curr Opin Biotechnol. 2017 Oct;47:51-58. doi: 10.1016/j.copbio.2017.05.006. Epub 2017 Jun 21. Review.


In Vitro Models to Study Human Lung Development, Disease and Homeostasis.

Miller AJ, Spence JR.

Physiology (Bethesda). 2017 May;32(3):246-260. doi: 10.1152/physiol.00041.2016. Review.

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