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Items: 1 to 20 of 32

1.

Clostridioides difficile Biology: Sporulation, Germination, and Corresponding Therapies for C. difficile Infection.

Zhu D, Sorg JA, Sun X.

Front Cell Infect Microbiol. 2018 Feb 8;8:29. doi: 10.3389/fcimb.2018.00029. eCollection 2018. Review.

2.

Hierarchical recognition of amino acid co-germinants during Clostridioides difficile spore germination.

Shrestha R, Sorg JA.

Anaerobe. 2018 Feb;49:41-47. doi: 10.1016/j.anaerobe.2017.12.001. Epub 2017 Dec 6.

PMID:
29221987
3.

Using CRISPR-Cas9-mediated genome editing to generate C. difficile mutants defective in selenoproteins synthesis.

McAllister KN, Bouillaut L, Kahn JN, Self WT, Sorg JA.

Sci Rep. 2017 Nov 7;7(1):14672. doi: 10.1038/s41598-017-15236-5.

4.

A Clostridium difficile alanine racemase affects spore germination and accommodates serine as a substrate.

Shrestha R, Lockless SW, Sorg JA.

J Biol Chem. 2017 Jun 23;292(25):10735-10742. doi: 10.1074/jbc.M117.791749. Epub 2017 May 9.

5.

Effect of tcdR Mutation on Sporulation in the Epidemic Clostridium difficile Strain R20291.

Girinathan BP, Monot M, Boyle D, McAllister KN, Sorg JA, Dupuy B, Govind R.

mSphere. 2017 Feb 15;2(1). pii: e00383-16. doi: 10.1128/mSphere.00383-16. eCollection 2017 Jan-Feb.

6.

Dipicolinic Acid Release by Germinating Clostridium difficile Spores Occurs through a Mechanosensing Mechanism.

Francis MB, Sorg JA.

mSphere. 2016 Dec 14;1(6). pii: e00306-16. eCollection 2016 Nov-Dec.

7.

Germinants and Their Receptors in Clostridia.

Bhattacharjee D, McAllister KN, Sorg JA.

J Bacteriol. 2016 Sep 22;198(20):2767-75. doi: 10.1128/JB.00405-16. Print 2016 Oct 15. Review.

8.

Detecting Cortex Fragments During Bacterial Spore Germination.

Francis MB, Sorg JA.

J Vis Exp. 2016 Jun 25;(112). doi: 10.3791/54146.

9.

Reexamining the Germination Phenotypes of Several Clostridium difficile Strains Suggests Another Role for the CspC Germinant Receptor.

Bhattacharjee D, Francis MB, Ding X, McAllister KN, Shrestha R, Sorg JA.

J Bacteriol. 2015 Dec 14;198(5):777-86. doi: 10.1128/JB.00908-15.

10.

Identification of a Novel Lipoprotein Regulator of Clostridium difficile Spore Germination.

Fimlaid KA, Jensen O, Donnelly ML, Francis MB, Sorg JA, Shen A.

PLoS Pathog. 2015 Oct 23;11(10):e1005239. doi: 10.1371/journal.ppat.1005239. eCollection 2015 Oct.

11.

Effects of surotomycin on Clostridium difficile viability and toxin production in vitro.

Bouillaut L, McBride S, Sorg JA, Schmidt DJ, Suarez JM, Tzipori S, Mascio C, Chesnel L, Sonenshein AL.

Antimicrob Agents Chemother. 2015 Jul;59(7):4199-205. doi: 10.1128/AAC.00275-15. Epub 2015 May 4.

12.

Spore Cortex Hydrolysis Precedes Dipicolinic Acid Release during Clostridium difficile Spore Germination.

Francis MB, Allen CA, Sorg JA.

J Bacteriol. 2015 Jul;197(14):2276-83. doi: 10.1128/JB.02575-14. Epub 2015 Apr 27.

13.

Microbial bile acid metabolic clusters: the bouncers at the bar.

Sorg JA.

Cell Host Microbe. 2014 Nov 12;16(5):551-2. doi: 10.1016/j.chom.2014.10.015. Epub 2014 Nov 12.

14.

Clostridium difficile spore biology: sporulation, germination, and spore structural proteins.

Paredes-Sabja D, Shen A, Sorg JA.

Trends Microbiol. 2014 Jul;22(7):406-16. doi: 10.1016/j.tim.2014.04.003. Epub 2014 May 7. Review.

15.

Muricholic acids inhibit Clostridium difficile spore germination and growth.

Francis MB, Allen CA, Sorg JA.

PLoS One. 2013 Sep 9;8(9):e73653. doi: 10.1371/journal.pone.0073653. eCollection 2013.

16.

Bile acid recognition by the Clostridium difficile germinant receptor, CspC, is important for establishing infection.

Francis MB, Allen CA, Shrestha R, Sorg JA.

PLoS Pathog. 2013 May;9(5):e1003356. doi: 10.1371/journal.ppat.1003356. Epub 2013 May 9.

17.

Site-directed mutations in the lanthipeptide mutacin 1140.

Chen S, Wilson-Stanford S, Cromwell W, Hillman JD, Guerrero A, Allen CA, Sorg JA, Smith L.

Appl Environ Microbiol. 2013 Jul;79(13):4015-23. doi: 10.1128/AEM.00704-13. Epub 2013 Apr 19.

18.

Small molecule inhibitor of lipoteichoic acid synthesis is an antibiotic for Gram-positive bacteria.

Richter SG, Elli D, Kim HK, Hendrickx AP, Sorg JA, Schneewind O, Missiakas D.

Proc Natl Acad Sci U S A. 2013 Feb 26;110(9):3531-6. doi: 10.1073/pnas.1217337110. Epub 2013 Feb 11.

19.

Both fidaxomicin and vancomycin inhibit outgrowth of Clostridium difficile spores.

Allen CA, Babakhani F, Sears P, Nguyen L, Sorg JA.

Antimicrob Agents Chemother. 2013 Jan;57(1):664-7. doi: 10.1128/AAC.01611-12. Epub 2012 Nov 12.

20.

Genetic manipulation of Clostridium difficile.

Bouillaut L, McBride SM, Sorg JA.

Curr Protoc Microbiol. 2011 Feb;Chapter 9:Unit 9A.2. doi: 10.1002/9780471729259.mc09a02s20.

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