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Items: 1 to 20 of 52

1.

Age and frailty as risk factors for the development of osteoarthritis.

O'Brien MS, McDougall JJ.

Mech Ageing Dev. 2019 Mar 18;180:21-28. doi: 10.1016/j.mad.2019.03.003. [Epub ahead of print] Review.

PMID:
30898635
2.

Intraarticular senescent chondrocytes impair the cartilage regeneration capacity of mesenchymal stem cells.

Cao X, Luo P, Huang J, Liang C, He J, Wang Z, Shan D, Peng C, Wu S.

Stem Cell Res Ther. 2019 Mar 12;10(1):86. doi: 10.1186/s13287-019-1193-1.

3.

Mitochondria and cellular senescence: Implications for musculoskeletal ageing.

Habiballa L, Salmonowicz H, Passos JF.

Free Radic Biol Med. 2019 Feb 20;132:3-10. doi: 10.1016/j.freeradbiomed.2018.10.417. Epub 2018 Oct 15. Review.

PMID:
30336251
4.

Secreted α-Klotho maintains cartilage tissue homeostasis by repressing NOS2 and ZIP8-MMP13 catabolic axis.

Chuchana P, Mausset-Bonnefont AL, Mathieu M, Espinoza F, Teigell M, Toupet K, Ripoll C, Djouad F, Noel D, Jorgensen C, Brondello JM.

Aging (Albany NY). 2018 Jun 19;10(6):1442-1453. doi: 10.18632/aging.101481.

5.

Major traits of the senescent phenotype of nucleus pulposus intervertebral disc cells persist under the specific microenvironmental conditions of the tissue.

Kouroumalis A, Mavrogonatou E, Savvidou OD, Papagelopoulos PJ, Pratsinis H, Kletsas D.

Mech Ageing Dev. 2019 Jan;177:118-127. doi: 10.1016/j.mad.2018.05.007. Epub 2018 May 17.

PMID:
29778758
6.

Ascorbic Acid Attenuates Senescence of Human Osteoarthritic Osteoblasts.

Burger MG, Steinitz A, Geurts J, Pippenger BE, Schaefer DJ, Martin I, Barbero A, Pelttari K.

Int J Mol Sci. 2017 Nov 24;18(12). pii: E2517. doi: 10.3390/ijms18122517.

7.

Endoplasmic reticulum stress participates in the progress of senescence and apoptosis of osteoarthritis chondrocytes.

Liu Y, Zhu H, Yan X, Gu H, Gu Z, Liu F.

Biochem Biophys Res Commun. 2017 Sep 16;491(2):368-373. doi: 10.1016/j.bbrc.2017.07.094. Epub 2017 Jul 17.

PMID:
28728848
8.

Local clearance of senescent cells attenuates the development of post-traumatic osteoarthritis and creates a pro-regenerative environment.

Jeon OH, Kim C, Laberge RM, Demaria M, Rathod S, Vasserot AP, Chung JW, Kim DH, Poon Y, David N, Baker DJ, van Deursen JM, Campisi J, Elisseeff JH.

Nat Med. 2017 Jun;23(6):775-781. doi: 10.1038/nm.4324. Epub 2017 Apr 24.

9.

Characterisation of a divergent progenitor cell sub-populations in human osteoarthritic cartilage: the role of telomere erosion and replicative senescence.

Fellows CR, Williams R, Davies IR, Gohil K, Baird DM, Fairclough J, Rooney P, Archer CW, Khan IM.

Sci Rep. 2017 Feb 2;7:41421. doi: 10.1038/srep41421.

10.

Cellular senescence in osteoarthritis pathology.

McCulloch K, Litherland GJ, Rai TS.

Aging Cell. 2017 Apr;16(2):210-218. doi: 10.1111/acel.12562. Epub 2017 Jan 26. Review.

11.

Transplanted Senescent Cells Induce an Osteoarthritis-Like Condition in Mice.

Xu M, Bradley EW, Weivoda MM, Hwang SM, Pirtskhalava T, Decklever T, Curran GL, Ogrodnik M, Jurk D, Johnson KO, Lowe V, Tchkonia T, Westendorf JJ, Kirkland JL.

J Gerontol A Biol Sci Med Sci. 2017 Jun 1;72(6):780-785. doi: 10.1093/gerona/glw154.

12.

Moderate treadmill running exercise prior to tendon injury enhances wound healing in aging rats.

Zhang J, Yuan T, Wang JH.

Oncotarget. 2016 Feb 23;7(8):8498-512. doi: 10.18632/oncotarget.7381.

13.

Inhibition of senescence and promotion of the proliferation of chondrocytes from articular cartilage by CsA and FK506 involves inhibition of p38MAPK.

Kang SW, Kim J, Shin DY.

Mech Ageing Dev. 2016 Jan;153:7-13. doi: 10.1016/j.mad.2015.12.002. Epub 2015 Dec 15.

PMID:
26704447
14.

Regulation of senescence associated signaling mechanisms in chondrocytes for cartilage tissue regeneration.

Ashraf S, Cha BH, Kim JS, Ahn J, Han I, Park H, Lee SH.

Osteoarthritis Cartilage. 2016 Feb;24(2):196-205. doi: 10.1016/j.joca.2015.07.008. Epub 2015 Jul 16. Review.

15.

Chondrosenescence: definition, hallmarks and potential role in the pathogenesis of osteoarthritis.

Mobasheri A, Matta C, Zákány R, Musumeci G.

Maturitas. 2015 Mar;80(3):237-44. doi: 10.1016/j.maturitas.2014.12.003. Epub 2014 Dec 24. Review.

16.

Age-related degeneration of articular cartilage in the pathogenesis of osteoarthritis: molecular markers of senescent chondrocytes.

Musumeci G, Szychlinska MA, Mobasheri A.

Histol Histopathol. 2015 Jan;30(1):1-12. doi: 10.14670/HH-30.1. Epub 2014 Jul 10. Review.

PMID:
25010513
17.

Involvement of ERCC1 in the pathogenesis of osteoarthritis through the modulation of apoptosis and cellular senescence.

Takayama K, Kawakami Y, Lee S, Greco N, Lavasani M, Mifune Y, Cummins JH, Yurube T, Kuroda R, Kurosaka M, Fu FH, Huard J.

J Orthop Res. 2014 Oct;32(10):1326-32. doi: 10.1002/jor.22656. Epub 2014 Jun 25.

18.

p16(INK4a) exerts an anti-inflammatory effect through accelerated IRAK1 degradation in macrophages.

Murakami Y, Mizoguchi F, Saito T, Miyasaka N, Kohsaka H.

J Immunol. 2012 Nov 15;189(10):5066-72. doi: 10.4049/jimmunol.1103156. Epub 2012 Oct 12.

19.

Cellular senescence occurring in the rabbit medial collateral ligament during healing.

Hsu WH, Peng KT, Lai LJ, Hung CH, Chang PJ.

J Orthop Res. 2013 Jan;31(1):81-90. doi: 10.1002/jor.22194. Epub 2012 Sep 5.

20.

Alpha fucosidase and beta galactosidase in serum of a Lyme disease patients as a possible marker of accelerated senescence - a preliminary study.

Wasiluk A, Waszkiewicz N, Szajda SD, Wojewódzka-Żelezniakowicz M, Kępka A, Minarowska A, Zwierz ZW, Pancewicz S, Ładny JR, Zwierz K.

Folia Histochem Cytobiol. 2012 Jul 5;50(2):270-4.

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