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Items: 1 to 20 of 43

1.

p53 Functions in Adipose Tissue Metabolism and Homeostasis.

Krstic J, Reinisch I, Schupp M, Schulz TJ, Prokesch A.

Int J Mol Sci. 2018 Sep 4;19(9). pii: E2622. doi: 10.3390/ijms19092622. Review.

2.

Liver-secreted RBP4 does not impair glucose homeostasis in mice.

Fedders R, Muenzner M, Weber P, Sommerfeld M, Knauer M, Kedziora S, Kast N, Heidenreich S, Raila J, Weger S, Henze A, Schupp M.

J Biol Chem. 2018 Sep 28;293(39):15269-15276. doi: 10.1074/jbc.RA118.004294. Epub 2018 Aug 20.

PMID:
30126844
3.

Loss of the Hematopoietic Stem Cell Factor GATA2 in the Osteogenic Lineage Impairs Trabecularization and Mechanical Strength of Bone.

Tolkachov A, Fischer C, Ambrosi TH, Bothe M, Han CT, Muenzner M, Mathia S, Salminen M, Seifert G, Thiele M, Duda GN, Meijsing SH, Sauer S, Schulz TJ, Schupp M.

Mol Cell Biol. 2018 May 29;38(12). pii: e00599-17. doi: 10.1128/MCB.00599-17. Print 2018 Jun 15.

4.

p53 as a Dichotomous Regulator of Liver Disease: The Dose Makes the Medicine.

Krstic J, Galhuber M, Schulz TJ, Schupp M, Prokesch A.

Int J Mol Sci. 2018 Mar 20;19(3). pii: E921. doi: 10.3390/ijms19030921. Review.

5.

Selective Mineralocorticoid Receptor Cofactor Modulation as Molecular Basis for Finerenone's Antifibrotic Activity.

Grune J, Beyhoff N, Smeir E, Chudek R, Blumrich A, Ban Z, Brix S, Betz IR, Schupp M, Foryst-Ludwig A, Klopfleisch R, Stawowy P, Houtman R, Kolkhof P, Kintscher U.

Hypertension. 2018 Apr;71(4):599-608. doi: 10.1161/HYPERTENSIONAHA.117.10360. Epub 2018 Feb 5.

PMID:
29437893
6.

Retinol saturase coordinates liver metabolism by regulating ChREBP activity.

Heidenreich S, Witte N, Weber P, Goehring I, Tolkachov A, von Loeffelholz C, Döcke S, Bauer M, Stockmann M, Pfeiffer AFH, Birkenfeld AL, Pietzke M, Kempa S, Muenzner M, Schupp M.

Nat Commun. 2017 Aug 30;8(1):384. doi: 10.1038/s41467-017-00430-w.

7.

Reciprocal regulation of carbon monoxide metabolism and the circadian clock.

Klemz R, Reischl S, Wallach T, Witte N, Jürchott K, Klemz S, Lang V, Lorenzen S, Knauer M, Heidenreich S, Xu M, Ripperger JA, Schupp M, Stanewsky R, Kramer A.

Nat Struct Mol Biol. 2017 Jan;24(1):15-22. doi: 10.1038/nsmb.3331. Epub 2016 Nov 28.

PMID:
27892932
8.

Liver p53 is stabilized upon starvation and required for amino acid catabolism and gluconeogenesis.

Prokesch A, Graef FA, Madl T, Kahlhofer J, Heidenreich S, Schumann A, Moyschewitz E, Pristoynik P, Blaschitz A, Knauer M, Muenzner M, Bogner-Strauss JG, Dohr G, Schulz TJ, Schupp M.

FASEB J. 2017 Feb;31(2):732-742. doi: 10.1096/fj.201600845R. Epub 2016 Nov 3.

9.

Loss of BMP receptor type 1A in murine adipose tissue attenuates age-related onset of insulin resistance.

Schulz TJ, Graja A, Huang TL, Xue R, An D, Poehle-Kronawitter S, Lynes MD, Tolkachov A, O'Sullivan LE, Hirshman MF, Schupp M, Goodyear LJ, Mishina Y, Tseng YH.

Diabetologia. 2016 Aug;59(8):1769-77. doi: 10.1007/s00125-016-3990-8. Epub 2016 May 21.

10.

Diabetes prevalence in NZO females depends on estrogen action on liver fat content.

Lubura M, Hesse D, Kraemer M, Hallahan N, Schupp M, von Löffelholz C, Kriebel J, Rudovich N, Pfeiffer A, John C, Scheja L, Heeren J, Koliaki C, Roden M, Schürmann A.

Am J Physiol Endocrinol Metab. 2015 Dec 15;309(12):E968-80. doi: 10.1152/ajpendo.00338.2015. Epub 2015 Oct 20.

11.

FABP4-Cre Mediated Expression of Constitutively Active ChREBP Protects Against Obesity, Fatty Liver, and Insulin Resistance.

Nuotio-Antar AM, Poungvarin N, Li M, Schupp M, Mohammad M, Gerard S, Zou F, Chan L.

Endocrinology. 2015 Nov;156(11):4020-32. doi: 10.1210/en.2015-1210. Epub 2015 Aug 6.

12.

The Glucose Sensor ChREBP Links De Novo Lipogenesis to PPARγ Activity and Adipocyte Differentiation.

Witte N, Muenzner M, Rietscher J, Knauer M, Heidenreich S, Nuotio-Antar AM, Graef FA, Fedders R, Tolkachov A, Goehring I, Schupp M.

Endocrinology. 2015 Nov;156(11):4008-19. doi: 10.1210/EN.2015-1209. Epub 2015 Jul 16.

PMID:
26181104
13.

Retinol binding protein 4 and its membrane receptors: a metabolic perspective.

Fedders R, Muenzner M, Schupp M.

Horm Mol Biol Clin Investig. 2015 Apr;22(1):27-37. doi: 10.1515/hmbci-2015-0013. Review.

PMID:
25941915
14.

The mammalian INDY homolog is induced by CREB in a rat model of type 2 diabetes.

Neuschäfer-Rube F, Lieske S, Kuna M, Henkel J, Perry RJ, Erion DM, Pesta D, Willmes DM, Brachs S, von Loeffelholz C, Tolkachov A, Schupp M, Pathe-Neuschäfer-Rube A, Pfeiffer AF, Shulman GI, Püschel GP, Birkenfeld AL.

Diabetes. 2014 Mar;63(3):1048-57. doi: 10.2337/db13-0749. Epub 2013 Nov 12.

15.

Metabolite and transcriptome analysis during fasting suggest a role for the p53-Ddit4 axis in major metabolic tissues.

Schupp M, Chen F, Briggs ER, Rao S, Pelzmann HJ, Pessentheiner AR, Bogner-Strauss JG, Lazar MA, Baldwin D, Prokesch A.

BMC Genomics. 2013 Nov 5;14:758. doi: 10.1186/1471-2164-14-758.

16.

Retinol-binding protein 4 and its membrane receptor STRA6 control adipogenesis by regulating cellular retinoid homeostasis and retinoic acid receptor α activity.

Muenzner M, Tuvia N, Deutschmann C, Witte N, Tolkachov A, Valai A, Henze A, Sander LE, Raila J, Schupp M.

Mol Cell Biol. 2013 Oct;33(20):4068-82. doi: 10.1128/MCB.00221-13. Epub 2013 Aug 19.

17.

GTPase ARFRP1 is essential for normal hepatic glycogen storage and insulin-like growth factor 1 secretion.

Hesse D, Jaschke A, Kanzleiter T, Witte N, Augustin R, Hommel A, Püschel GP, Petzke KJ, Joost HG, Schupp M, Schürmann A.

Mol Cell Biol. 2012 Nov;32(21):4363-74. doi: 10.1128/MCB.00522-12. Epub 2012 Aug 27.

18.

Histone deacetylase 6 (HDAC6) is an essential modifier of glucocorticoid-induced hepatic gluconeogenesis.

Winkler R, Benz V, Clemenz M, Bloch M, Foryst-Ludwig A, Wardat S, Witte N, Trappiel M, Namsolleck P, Mai K, Spranger J, Matthias G, Roloff T, Truee O, Kappert K, Schupp M, Matthias P, Kintscher U.

Diabetes. 2012 Feb;61(2):513-23. doi: 10.2337/db11-0313. Epub 2011 Dec 30.

19.

Repressor transcription factor 7-like 1 promotes adipogenic competency in precursor cells.

Cristancho AG, Schupp M, Lefterova MI, Cao S, Cohen DM, Chen CS, Steger DJ, Lazar MA.

Proc Natl Acad Sci U S A. 2011 Sep 27;108(39):16271-6. doi: 10.1073/pnas.1109409108. Epub 2011 Sep 13.

20.

Endogenous ligands for nuclear receptors: digging deeper.

Schupp M, Lazar MA.

J Biol Chem. 2010 Dec 24;285(52):40409-15. doi: 10.1074/jbc.R110.182451. Epub 2010 Oct 18. Review.

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