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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1928 1
1933 1
1938 1
1961 1
1962 1
1964 1
1967 2
1968 1
1969 1
1971 3
1972 5
1974 5
1975 20
1976 41
1977 34
1978 40
1979 38
1980 53
1981 87
1982 94
1983 103
1984 110
1985 123
1986 142
1987 161
1988 201
1989 226
1990 269
1991 258
1992 315
1993 342
1994 393
1995 407
1996 458
1997 526
1998 562
1999 611
2000 655
2001 659
2002 623
2003 746
2004 832
2005 923
2006 907
2007 956
2008 1074
2009 1193
2010 1302
2011 1429
2012 1494
2013 1594
2014 1841
2015 2261
2016 1655
2017 1484
2018 1863
2019 2054
2020 2353
2021 2576
2022 2435
2023 2286
2024 699

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37,208 results

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Page 1
Annexin-A1: Therapeutic Potential in Microvascular Disease.
Purvis GSD, Solito E, Thiemermann C. Purvis GSD, et al. Front Immunol. 2019 Apr 30;10:938. doi: 10.3389/fimmu.2019.00938. eCollection 2019. Front Immunol. 2019. PMID: 31114582 Free PMC article. Review.
Annexin-A1 (ANXA1) was first discovered in the early 1980's as a protein, which mediates (some of the) anti-inflammatory effects of glucocorticoids. ...In the present mini review, we will endeavor to give an overview of ANXA1 biology in relation to inflammation and …
Annexin-A1 (ANXA1) was first discovered in the early 1980's as a protein, which mediates (some of the) anti-inflammatory effec …
Purinergic receptors in cognitive disturbances.
Illes P, Ulrich H, Chen JF, Tang Y. Illes P, et al. Neurobiol Dis. 2023 Sep;185:106229. doi: 10.1016/j.nbd.2023.106229. Epub 2023 Jul 13. Neurobiol Dis. 2023. PMID: 37453562 Free article. Review.
Purinergic receptors (Rs) of the ATP/ADP, UTP/UDP (P2X, P2Y) and adenosine (A1, A2A)-sensitive classes broadly interfere with cognitive processes both under quasi normal and disease conditions. ...Dementia is a leading symptom in Alzheimer's disease (A …
Purinergic receptors (Rs) of the ATP/ADP, UTP/UDP (P2X, P2Y) and adenosine (A1, A2A)-sensitive classes broadly interfere with cogniti …
Adenosine receptors and Huntington's disease.
Lee CF, Chern Y. Lee CF, et al. Int Rev Neurobiol. 2014;119:195-232. doi: 10.1016/B978-0-12-801022-8.00010-6. Int Rev Neurobiol. 2014. PMID: 25175968 Review.
Adenosine regulates important pathophysiological functions via four distinct adenosine receptor subtypes (A1, A2A, A2B, and A3). The A1 and A2A adenosine receptors (A1R and A2AR) are major targets of caffeine and have been extensively investigated. Huntington's …
Adenosine regulates important pathophysiological functions via four distinct adenosine receptor subtypes (A1, A2A, A2B, and A3). The …
A Comprehensive Analysis of the Role of hnRNP A1 Function and Dysfunction in the Pathogenesis of Neurodegenerative Disease.
Clarke JP, Thibault PA, Salapa HE, Levin MC. Clarke JP, et al. Front Mol Biosci. 2021 Apr 12;8:659610. doi: 10.3389/fmolb.2021.659610. eCollection 2021. Front Mol Biosci. 2021. PMID: 33912591 Free PMC article. Review.
While a plethora of knowledge is known about the function and dysfunction of hnRNP A1 in diseases other than neurodegenerative disease (e.g., cancer), numerous studies in amyotrophic lateral sclerosis, frontotemporal lobar degeneration, multiple sclerosis, sp …
While a plethora of knowledge is known about the function and dysfunction of hnRNP A1 in diseases other than neurodegenerative …
Single cell landscape of parietal epithelial cells in healthy and diseased states.
Liu WB, Huang GR, Liu BL, Hu HK, Geng J, Rui HL, Gao C, Huang YJ, Huo GY, Mao JR, Lu CJ, Xu AL. Liu WB, et al. Kidney Int. 2023 Jul;104(1):108-123. doi: 10.1016/j.kint.2023.03.036. Epub 2023 Apr 24. Kidney Int. 2023. PMID: 37100348 Free article.
Our analysis identified five distinct PEC subpopulations: PEC-A1, PEC-A2, PEC-A3, PEC-A4 and PEC-B. Among these subpopulations, PEC- A1 and PEC-A2 were characterized as podocyte progenitors while PEC-A4 represented tubular progenitors. ...
Our analysis identified five distinct PEC subpopulations: PEC-A1, PEC-A2, PEC-A3, PEC-A4 and PEC-B. Among these subpopulations, PEC- …
The advantageous role of annexin A1 in cardiovascular disease.
de Jong R, Leoni G, Drechsler M, Soehnlein O. de Jong R, et al. Cell Adh Migr. 2017 May 4;11(3):261-274. doi: 10.1080/19336918.2016.1259059. Epub 2016 Nov 18. Cell Adh Migr. 2017. PMID: 27860536 Free PMC article. Review.
However, uncontrolled and unresolved inflammation can lead to tissue damage and chronic inflammatory diseases. Therefore, active resolution of inflammation is essential to restore tissue homeostasis. ...Additionally, this review details the therapeutic relevance of ANXA1 a …
However, uncontrolled and unresolved inflammation can lead to tissue damage and chronic inflammatory diseases. Therefore, active reso …
CD49f Is a Novel Marker of Functional and Reactive Human iPSC-Derived Astrocytes.
Barbar L, Jain T, Zimmer M, Kruglikov I, Sadick JS, Wang M, Kalpana K, Rose IVL, Burstein SR, Rusielewicz T, Nijsure M, Guttenplan KA, di Domenico A, Croft G, Zhang B, Nobuta H, Hébert JM, Liddelow SA, Fossati V. Barbar L, et al. Neuron. 2020 Aug 5;107(3):436-453.e12. doi: 10.1016/j.neuron.2020.05.014. Epub 2020 Jun 1. Neuron. 2020. PMID: 32485136 Free PMC article.
Notably, CD49f(+) hiPSC-astrocytes respond to inflammatory stimuli, acquiring an A1-like reactive state, in which they display impaired phagocytosis and glutamate uptake and fail to support neuronal maturation. Most importantly, we show that conditioned medium from human r …
Notably, CD49f(+) hiPSC-astrocytes respond to inflammatory stimuli, acquiring an A1-like reactive state, in which they display impair …
Annexin A1 based inflammation resolving mediators and nanomedicines for inflammatory bowel disease therapy.
Xu R, Weber MC, Hu X, Neumann PA, Kamaly N. Xu R, et al. Semin Immunol. 2022 Nov;61-64:101664. doi: 10.1016/j.smim.2022.101664. Epub 2022 Oct 25. Semin Immunol. 2022. PMID: 36306664 Free article. Review.
Inflammatory bowel diseases (IBD) such as Crohn's Disease (CD) and Ulcerative Colitis (UC) are chronic, progressive, and relapsing disorders of the gastrointestinal tract (GIT), characterised by intestinal epithelial injury and inflammation. ...Resolution med …
Inflammatory bowel diseases (IBD) such as Crohn's Disease (CD) and Ulcerative Colitis (UC) are chronic, progressive, an …
Adenosine receptors and Huntington's disease: implications for pathogenesis and therapeutics.
Blum D, Hourez R, Galas MC, Popoli P, Schiffmann SN. Blum D, et al. Lancet Neurol. 2003 Jun;2(6):366-74. doi: 10.1016/s1474-4422(03)00411-3. Lancet Neurol. 2003. PMID: 12849153 Review.
Huntington's disease (HD) is a devastating hereditary neurodegenerative disorder, the progression of which cannot be prevented by any neuroprotective approach, despite major advances in the understanding of its pathogenesis. ...Adenosine has neuroprotective potentia …
Huntington's disease (HD) is a devastating hereditary neurodegenerative disorder, the progression of which cannot be prevented …
37,208 results
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