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Items: 1 to 20 of 227

1.

Association of Whole-Genome and NETRIN1 Signaling Pathway-Derived Polygenic Risk Scores for Major Depressive Disorder and White Matter Microstructure in the UK Biobank.

Barbu MC, Zeng Y, Shen X, Cox SR, Clarke TK, Gibson J, Adams MJ, Johnstone M, Haley CS, Lawrie SM, Deary IJ; Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium; 23andMe Research Team, McIntosh AM, Whalley HC.

Biol Psychiatry Cogn Neurosci Neuroimaging. 2018 Jul 31. pii: S2451-9022(18)30181-2. doi: 10.1016/j.bpsc.2018.07.006. [Epub ahead of print]

PMID:
30197049
2.

Effect of cytochrome CYP2C19 metabolizing activity on antidepressant response and side effects: Meta-analysis of data from genome-wide association studies.

Fabbri C, Tansey KE, Perlis RH, Hauser J, Henigsberg N, Maier W, Mors O, Placentino A, Rietschel M, Souery D, Breen G, Curtis C, Lee SH, Newhouse S, Patel H, O'Donovan M, Lewis G, Jenkins G, Weinshilboum RM, Farmer A, Aitchison KJ, Craig I, McGuffin P, Schruers K, Biernacka JM, Uher R, Lewis CM.

Eur Neuropsychopharmacol. 2018 Aug;28(8):945-954. doi: 10.1016/j.euroneuro.2018.05.009. Epub 2018 Jun 28.

PMID:
30135031
3.

Cohort study of the relationship between individual psychotherapy and pregnancy outcomes.

Snapper LA, Hart KL, Venkatesh KK, Kaimal AJ, Perlis RH.

J Affect Disord. 2018 Oct 15;239:253-257. doi: 10.1016/j.jad.2018.05.083. Epub 2018 Jul 6.

PMID:
30029152
4.

Genomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes.

Bipolar Disorder and Schizophrenia Working Group of the Psychiatric Genomics Consortium. Electronic address: douglas.ruderfer@vanderbilt.edu; Bipolar Disorder and Schizophrenia Working Group of the Psychiatric Genomics Consortium.

Cell. 2018 Jun 14;173(7):1705-1715.e16. doi: 10.1016/j.cell.2018.05.046.

PMID:
29906448
5.

Analysis of the Influence of microRNAs in Lithium Response in Bipolar Disorder.

Reinbold CS, Forstner AJ, Hecker J, Fullerton JM, Hoffmann P, Hou L, Heilbronner U, Degenhardt F, Adli M, Akiyama K, Akula N, Ardau R, Arias B, Backlund L, Benabarre A, Bengesser S, Bhattacharjee AK, Biernacka JM, Birner A, Marie-Claire C, Cervantes P, Chen GB, Chen HC, Chillotti C, Clark SR, Colom F, Cousins DA, Cruceanu C, Czerski PM, Dayer A, Étain B, Falkai P, Frisén L, Gard S, Garnham JS, Goes FS, Grof P, Gruber O, Hashimoto R, Hauser J, Herms S, Jamain S, Jiménez E, Kahn JP, Kassem L, Kittel-Schneider S, Kliwicki S, König B, Kusumi I, Lackner N, Laje G, Landén M, Lavebratt C, Leboyer M, Leckband SG, López Jaramillo CA, MacQueen G, Manchia M, Martinsson L, Mattheisen M, McCarthy MJ, McElroy SL, Mitjans M, Mondimore FM, Monteleone P, Nievergelt CM, Ösby U, Ozaki N, Perlis RH, Pfennig A, Reich-Erkelenz D, Rouleau GA, Schofield PR, Schubert KO, Schweizer BW, Seemüller F, Severino G, Shekhtman T, Shilling PD, Shimoda K, Simhandl C, Slaney CM, Smoller JW, Squassina A, Stamm TJ, Stopkova P, Tighe SK, Tortorella A, Turecki G, Volkert J, Witt SH, Wright AJ, Young LT, Zandi PP, Potash JB, DePaulo JR, Bauer M, Reininghaus E, Novák T, Aubry JM, Maj M, Baune BT, Mitchell PB, Vieta E, Frye MA, Rybakowski JK, Kuo PH, Kato T, Grigoroiu-Serbanescu M, Reif A, Del Zompo M, Bellivier F, Schalling M, Wray NR, Kelsoe JR, Alda M, McMahon FJ, Schulze TG, Rietschel M, Nöthen MM, Cichon S.

Front Psychiatry. 2018 May 31;9:207. doi: 10.3389/fpsyt.2018.00207. eCollection 2018.

6.

No Association Between Antidepressant Efficacy and rs28365143 in Corticotropin-Releasing Hormone Binding Protein in a Large Meta-Analysis.

Fabbri C, Lewis CM, Perlis RH, Uher R.

Am J Psychiatry. 2018 Jun 1;175(6):575-576. doi: 10.1176/appi.ajp.2018.18010070. No abstract available.

PMID:
29869543
7.

Impairment in delay discounting in schizophrenia and schizoaffective disorder but not primary mood disorders.

Brown HE, Hart KL, Snapper LA, Roffman JL, Perlis RH.

NPJ Schizophr. 2018 May 28;4(1):9. doi: 10.1038/s41537-018-0050-z.

8.

Pharmacogenetic testing among patients with mood and anxiety disorders is associated with decreased utilization and cost: A propensity-score matched study.

Perlis RH, Mehta R, Edwards AM, Tiwari A, Imbens GW.

Depress Anxiety. 2018 May 7. doi: 10.1002/da.22742. [Epub ahead of print]

PMID:
29734486
9.

Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression.

Wray NR, Ripke S, Mattheisen M, Trzaskowski M, Byrne EM, Abdellaoui A, Adams MJ, Agerbo E, Air TM, Andlauer TMF, Bacanu SA, Bækvad-Hansen M, Beekman AFT, Bigdeli TB, Binder EB, Blackwood DRH, Bryois J, Buttenschøn HN, Bybjerg-Grauholm J, Cai N, Castelao E, Christensen JH, Clarke TK, Coleman JIR, Colodro-Conde L, Couvy-Duchesne B, Craddock N, Crawford GE, Crowley CA, Dashti HS, Davies G, Deary IJ, Degenhardt F, Derks EM, Direk N, Dolan CV, Dunn EC, Eley TC, Eriksson N, Escott-Price V, Kiadeh FHF, Finucane HK, Forstner AJ, Frank J, Gaspar HA, Gill M, Giusti-Rodríguez P, Goes FS, Gordon SD, Grove J, Hall LS, Hannon E, Hansen CS, Hansen TF, Herms S, Hickie IB, Hoffmann P, Homuth G, Horn C, Hottenga JJ, Hougaard DM, Hu M, Hyde CL, Ising M, Jansen R, Jin F, Jorgenson E, Knowles JA, Kohane IS, Kraft J, Kretzschmar WW, Krogh J, Kutalik Z, Lane JM, Li Y, Li Y, Lind PA, Liu X, Lu L, MacIntyre DJ, MacKinnon DF, Maier RM, Maier W, Marchini J, Mbarek H, McGrath P, McGuffin P, Medland SE, Mehta D, Middeldorp CM, Mihailov E, Milaneschi Y, Milani L, Mill J, Mondimore FM, Montgomery GW, Mostafavi S, Mullins N, Nauck M, Ng B, Nivard MG, Nyholt DR, O'Reilly PF, Oskarsson H, Owen MJ, Painter JN, Pedersen CB, Pedersen MG, Peterson RE, Pettersson E, Peyrot WJ, Pistis G, Posthuma D, Purcell SM, Quiroz JA, Qvist P, Rice JP, Riley BP, Rivera M, Saeed Mirza S, Saxena R, Schoevers R, Schulte EC, Shen L, Shi J, Shyn SI, Sigurdsson E, Sinnamon GBC, Smit JH, Smith DJ, Stefansson H, Steinberg S, Stockmeier CA, Streit F, Strohmaier J, Tansey KE, Teismann H, Teumer A, Thompson W, Thomson PA, Thorgeirsson TE, Tian C, Traylor M, Treutlein J, Trubetskoy V, Uitterlinden AG, Umbricht D, Van der Auwera S, van Hemert AM, Viktorin A, Visscher PM, Wang Y, Webb BT, Weinsheimer SM, Wellmann J, Willemsen G, Witt SH, Wu Y, Xi HS, Yang J, Zhang F; eQTLGen; 23andMe, Arolt V, Baune BT, Berger K, Boomsma DI, Cichon S, Dannlowski U, de Geus ECJ, DePaulo JR, Domenici E, Domschke K, Esko T, Grabe HJ, Hamilton SP, Hayward C, Heath AC, Hinds DA, Kendler KS, Kloiber S, Lewis G, Li QS, Lucae S, Madden PFA, Magnusson PK, Martin NG, McIntosh AM, Metspalu A, Mors O, Mortensen PB, Müller-Myhsok B, Nordentoft M, Nöthen MM, O'Donovan MC, Paciga SA, Pedersen NL, Penninx BWJH, Perlis RH, Porteous DJ, Potash JB, Preisig M, Rietschel M, Schaefer C, Schulze TG, Smoller JW, Stefansson K, Tiemeier H, Uher R, Völzke H, Weissman MM, Werge T, Winslow AR, Lewis CM, Levinson DF, Breen G, Børglum AD, Sullivan PF; Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium.

Nat Genet. 2018 May;50(5):668-681. doi: 10.1038/s41588-018-0090-3. Epub 2018 Apr 26.

PMID:
29700475
10.

Anxiety About Antidepressants.

Perlis RH.

Am J Psychiatry. 2018 Jun 1;175(6):500-501. doi: 10.1176/appi.ajp.2018.18040399. Epub 2018 Apr 25. No abstract available.

PMID:
29690791
11.

Genetic validation of bipolar disorder identified by automated phenotyping using electronic health records.

Chen CY, Lee PH, Castro VM, Minnier J, Charney AW, Stahl EA, Ruderfer DM, Murphy SN, Gainer V, Cai T, Jones I, Pato CN, Pato MT, Landén M, Sklar P, Perlis RH, Smoller JW.

Transl Psychiatry. 2018 Apr 18;8(1):86. doi: 10.1038/s41398-018-0133-7.

12.

Can a Framework Be Established for the Safe Use of Ketamine?

Freedman R, Brown AS, Cannon TD, Druss BG, Earls FJ, Escobar J, Hurd YL, Lewis DA, López-Jaramillo C, Luby J, Mayberg HS, Moffitt TE, Oquendo M, Perlis RH, Pine DS, Rush AJ, Tamminga CA, Tohen M, Vieta E, Wisner KL, Xin Y.

Am J Psychiatry. 2018 Jul 1;175(7):587-589. doi: 10.1176/appi.ajp.2018.18030290. Epub 2018 Apr 16. No abstract available.

PMID:
29656666
13.

Genome-wide association identifies a novel locus for delirium risk.

McCoy TH Jr, Hart K, Pellegrini A, Perlis RH.

Neurobiol Aging. 2018 Aug;68:160.e9-160.e14. doi: 10.1016/j.neurobiolaging.2018.03.008. Epub 2018 Mar 10.

PMID:
29631748
14.

Computational repositioning and preclinical validation of mifepristone for human vestibular schwannoma.

Sagers JE, Brown AS, Vasilijic S, M Lewis R, Sahin MI, Landegger LD, Perlis RH, Kohane IS, Welling DB, Patel CJ, Stankovic KM.

Sci Rep. 2018 Apr 3;8(1):5437. doi: 10.1038/s41598-018-23609-7.

15.

Genome-wide Association Study of Dimensional Psychopathology Using Electronic Health Records.

McCoy TH Jr, Castro VM, Hart KL, Pellegrini AM, Yu S, Cai T, Perlis RH.

Biol Psychiatry. 2018 Jun 15;83(12):1005-1011. doi: 10.1016/j.biopsych.2017.12.004. Epub 2018 Feb 26.

16.

High Throughput Phenotyping for Dimensional Psychopathology in Electronic Health Records.

McCoy TH Jr, Yu S, Hart KL, Castro VM, Brown HE, Rosenquist JN, Doyle AE, Vuijk PJ, Cai T, Perlis RH.

Biol Psychiatry. 2018 Jun 15;83(12):997-1004. doi: 10.1016/j.biopsych.2018.01.011. Epub 2018 Feb 26.

17.

Does Childhood Trauma Moderate Polygenic Risk for Depression? A Meta-analysis of 5765 Subjects From the Psychiatric Genomics Consortium.

Peyrot WJ, Van der Auwera S, Milaneschi Y, Dolan CV, Madden PAF, Sullivan PF, Strohmaier J, Ripke S, Rietschel M, Nivard MG, Mullins N, Montgomery GW, Henders AK, Heat AC, Fisher HL, Dunn EC, Byrne EM, Air TA; Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Baune BT, Breen G, Levinson DF, Lewis CM, Martin NG, Nelson EN, Boomsma DI, Grabe HJ, Wray NR, Penninx BWJH.

Biol Psychiatry. 2017 Sep 21. pii: S0006-3223(17)31993-5. doi: 10.1016/j.biopsych.2017.09.009. [Epub ahead of print]

PMID:
29129318
18.

Hair Cortisol in Twins: Heritability and Genetic Overlap with Psychological Variables and Stress-System Genes.

Rietschel L, Streit F, Zhu G, McAloney K, Frank J, Couvy-Duchesne B, Witt SH, Binz TM; CORtisolNETwork (CORNET) Consortium; Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium (PGC), McGrath J, Hickie IB, Hansell NK, Wright MJ, Gillespie NA, Forstner AJ, Schulze TG, Wüst S, Nöthen MM, Baumgartner MR, Walker BR, Crawford AA, Colodro-Conde L, Medland SE, Martin NG, Rietschel M.

Sci Rep. 2017 Nov 10;7(1):15351. doi: 10.1038/s41598-017-11852-3.

19.

Genetic Association of Major Depression With Atypical Features and Obesity-Related Immunometabolic Dysregulations.

Milaneschi Y, Lamers F, Peyrot WJ, Baune BT, Breen G, Dehghan A, Forstner AJ, Grabe HJ, Homuth G, Kan C, Lewis C, Mullins N, Nauck M, Pistis G, Preisig M, Rivera M, Rietschel M, Streit F, Strohmaier J, Teumer A, Van der Auwera S, Wray NR, Boomsma DI, Penninx BWJH; CHARGE Inflammation Working Group and the Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium.

JAMA Psychiatry. 2017 Dec 1;74(12):1214-1225. doi: 10.1001/jamapsychiatry.2017.3016.

PMID:
29049554
20.

Validation of Polygenic Scores for QT Interval in Clinical Populations.

Rosenberg MA, Lubitz SA, Lin H, Kosova G, Castro VM, Huang P, Ellinor PT, Perlis RH, Newton-Cheh C.

Circ Cardiovasc Genet. 2017 Oct;10(5). pii: e001724. doi: 10.1161/CIRCGENETICS.117.001724.

PMID:
28986454

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