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Items: 12

1.

Mitochondrial Arginase-2 is a cell autonomous regulator of CD8+ T cell function and anti-tumor efficacy.

Martí I Líndez AA, Dunand-Sauthier I, Conti M, Gobet F, Núñez N, Hannich JT, Riezman H, Geiger R, Piersigilli A, Hahn K, Lemeille S, Becher B, De Smedt T, Hugues S, Reith W.

JCI Insight. 2019 Nov 21. pii: 132975. doi: 10.1172/jci.insight.132975. [Epub ahead of print]

2.

Pseudomonas aeruginosa lectin LecB impairs keratinocyte fitness by abrogating growth factor signalling.

Landi A, Mari M, Kleiser S, Wolf T, Gretzmeier C, Wilhelm I, Kiritsi D, Thünauer R, Geiger R, Nyström A, Reggiori F, Claudinon J, Römer W.

Life Sci Alliance. 2019 Nov 15;2(6). pii: e201900422. doi: 10.26508/lsa.201900422. Print 2019 Dec.

3.

A single T cell epitope drives the neutralizing anti-drug antibody response to natalizumab in multiple sclerosis patients.

Cassotta A, Mikol V, Bertrand T, Pouzieux S, Le Parc J, Ferrari P, Dumas J, Auer M, Deisenhammer F, Gastaldi M, Franciotta D, Silacci-Fregni C, Fernandez Rodriguez B, Giacchetto-Sasselli I, Foglierini M, Jarrossay D, Geiger R, Sallusto F, Lanzavecchia A, Piccoli L.

Nat Med. 2019 Sep;25(9):1402-1407. doi: 10.1038/s41591-019-0568-2. Epub 2019 Sep 9.

PMID:
31501610
4.

Plasma cell deficiency in human subjects with heterozygous mutations in Sec61 translocon alpha 1 subunit (SEC61A1).

Schubert D, Klein MC, Hassdenteufel S, Caballero-Oteyza A, Yang L, Proietti M, Bulashevska A, Kemming J, Kühn J, Winzer S, Rusch S, Fliegauf M, Schäffer AA, Pfeffer S, Geiger R, Cavalié A, Cao H, Yang F, Li Y, Rizzi M, Eibel H, Kobbe R, Marks AL, Peppers BP, Hostoffer RW, Puck JM, Zimmermann R, Grimbacher B.

J Allergy Clin Immunol. 2018 Apr;141(4):1427-1438. doi: 10.1016/j.jaci.2017.06.042. Epub 2017 Aug 4.

5.

Social network architecture of human immune cells unveiled by quantitative proteomics.

Rieckmann JC, Geiger R, Hornburg D, Wolf T, Kveler K, Jarrossay D, Sallusto F, Shen-Orr SS, Lanzavecchia A, Mann M, Meissner F.

Nat Immunol. 2017 May;18(5):583-593. doi: 10.1038/ni.3693. Epub 2017 Mar 6.

PMID:
28263321
6.

L-Arginine Modulates T Cell Metabolism and Enhances Survival and Anti-tumor Activity.

Geiger R, Rieckmann JC, Wolf T, Basso C, Feng Y, Fuhrer T, Kogadeeva M, Picotti P, Meissner F, Mann M, Zamboni N, Sallusto F, Lanzavecchia A.

Cell. 2016 Oct 20;167(3):829-842.e13. doi: 10.1016/j.cell.2016.09.031. Epub 2016 Oct 13.

7.

Platelet-derived growth factor-α receptor is the cellular receptor for human cytomegalovirus gHgLgO trimer.

Kabanova A, Marcandalli J, Zhou T, Bianchi S, Baxa U, Tsybovsky Y, Lilleri D, Silacci-Fregni C, Foglierini M, Fernandez-Rodriguez BM, Druz A, Zhang B, Geiger R, Pagani M, Sallusto F, Kwong PD, Corti D, Lanzavecchia A, Perez L.

Nat Microbiol. 2016 Jun 6;1(8):16082. doi: 10.1038/nmicrobiol.2016.82.

8.

A LAIR1 insertion generates broadly reactive antibodies against malaria variant antigens.

Tan J, Pieper K, Piccoli L, Abdi A, Perez MF, Geiger R, Tully CM, Jarrossay D, Maina Ndungu F, Wambua J, Bejon P, Fregni CS, Fernandez-Rodriguez B, Barbieri S, Bianchi S, Marsh K, Thathy V, Corti D, Sallusto F, Bull P, Lanzavecchia A.

Nature. 2016 Jan 7;529(7584):105-109. doi: 10.1038/nature16450. Epub 2015 Dec 23.

9.

Investigating endocytic pathways to the endoplasmic reticulum and to the cytosol using SNAP-trap.

Geiger R, Luisoni S, Johnsson K, Greber UF, Helenius A.

Traffic. 2013 Jan;14(1):36-46. doi: 10.1111/tra.12018. Epub 2012 Nov 12.

10.

BAP31 and BiP are essential for dislocation of SV40 from the endoplasmic reticulum to the cytosol.

Geiger R, Andritschke D, Friebe S, Herzog F, Luisoni S, Heger T, Helenius A.

Nat Cell Biol. 2011 Sep 25;13(11):1305-14. doi: 10.1038/ncb2339.

PMID:
21947079
11.

Folding, quality control, and secretion of pancreatic ribonuclease in live cells.

Geiger R, Gautschi M, Thor F, Hayer A, Helenius A.

J Biol Chem. 2011 Feb 18;286(7):5813-22. doi: 10.1074/jbc.M110.171694. Epub 2010 Dec 14.

12.

Bulk flow revisited: transport of a soluble protein in the secretory pathway.

Thor F, Gautschi M, Geiger R, Helenius A.

Traffic. 2009 Dec;10(12):1819-30. doi: 10.1111/j.1600-0854.2009.00989.x. Epub 2009 Sep 16.

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