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Items: 1 to 20 of 1705

1.

Glycogen storage disease type Ia mice with less than 2% of normal hepatic glucose-6-phosphatase-α activity restored are at risk of developing hepatic tumors.

Kim GY, Lee YM, Kwon JH, Cho JH, Pan CJ, Starost MF, Mansfield BC, Chou JY.

Mol Genet Metab. 2017 Jan 10. pii: S1096-7192(16)30814-9. doi: 10.1016/j.ymgme.2017.01.003. [Epub ahead of print]

PMID:
28096054
2.

MiR-30c-5p ameliorates hepatic steatosis in leptin receptor-deficient (db/db) mice via down-regulating FASN.

Fan J, Li H, Nie X, Yin Z, Zhao Y, Chen C, Wang DW.

Oncotarget. 2017 Jan 9. doi: 10.18632/oncotarget.14561. [Epub ahead of print]

3.

Diabetes Mellitus-Induced Microvascular Destabilization in the Myocardium.

Hinkel R, Hoewe A, Renner S, Ng J, Lee S, Klett K, Kaczmarek V, Moretti A, Laugwitz KL, Skroblin P, Mayr M, Milting H, Dendorfer A, Reichart B, Wolf E, Kupatt C.

J Am Coll Cardiol. 2017 Jan 17;69(2):131-143. doi: 10.1016/j.jacc.2016.10.058.

PMID:
28081822
4.

Future of rAAV gene therapy: Platform for RNAi, Gene Editing and Beyond.

Valdmanis P, Kay MA.

Hum Gene Ther. 2017 Jan 10. doi: 10.1089/hum.2016.171. [Epub ahead of print]

PMID:
28073291
5.

Adeno-associated virus serotype rh.10 displays strong muscle tropism following intraperitoneal delivery.

Ai J, Li J, Gessler DJ, Su Q, Wei Q, Li H, Gao G.

Sci Rep. 2017 Jan 9;7:40336. doi: 10.1038/srep40336.

6.

Preparation of rAAV9 to Overexpress or Knockdown Genes in Mouse Hearts.

Ding J, Lin ZQ, Jiang JM, Seidman CE, Seidman JG, Pu WT, Wang DZ.

J Vis Exp. 2016 Dec 17;(118). doi: 10.3791/54787.

PMID:
28060283
7.

Comparison of serum rAAV serotype-specific antibodies in patients with Duchenne Muscular Dystrophy, Becker Muscular Dystrophy, Inclusion Body Myositis or GNE myopathy.

Zygmunt D, Crowe KE, Flanigan K, Martin PT.

Hum Gene Ther. 2017 Jan 2. doi: 10.1089/hum.2016.141. [Epub ahead of print]

PMID:
28042944
8.
9.

Tollip, an early regulator of the acute inflammatory response in the substantia nigra.

Humbert-Claude M, Duc D, Dwir D, Thieren L, Sandström von Tobel J, Begka C, Legueux F, Velin D, Maillard MH, Do KQ, Monnet-Tschudi F, Tenenbaum L.

J Neuroinflammation. 2016 Dec 7;13(1):303.

10.

Therapeutic Benefits and Adverse Effects of Combined Proangiogenic Gene Therapy in Mouse Critical Leg Ischemia.

Lebas B, Galley J, Renaud-Gabardos E, Pujol F, Lenfant F, Garmy-Susini B, Chaufour X, Prats AC.

Ann Vasc Surg. 2016 Nov 27. pii: S0890-5096(16)31264-X. doi: 10.1016/j.avsg.2016.08.027. [Epub ahead of print]

PMID:
27903483
11.

Recombinant Adeno-Associated Virus Serotype 6 (rAAV6) Potently and Preferentially Transduces Rat Astrocytes In vitro and In vivo.

Schober AL, Gagarkin DA, Chen Y, Gao G, Jacobson L, Mongin AA.

Front Cell Neurosci. 2016 Nov 11;10:262.

12.

Phase 2a Randomized Clinical Trial: Safety and Post Hoc Analysis of Subretinal rAAV.sFLT-1 for Wet Age-related Macular Degeneration.

Constable IJ, Pierce CM, Lai CM, Magno AL, Degli-Esposti MA, French MA, McAllister IL, Butler S, Barone SB, Schwartz SD, Blumenkranz MS, Rakoczy EP.

EBioMedicine. 2016 Dec;14:168-175. doi: 10.1016/j.ebiom.2016.11.016.

13.

Transfer of Therapeutic Genes into Fetal Rhesus Monkeys Using Recombinant Adeno-Associated Type I Viral Vectors.

Conlon TJ, Mah CS, Pacak CA, Rucker Henninger MB, Erger KE, Jorgensen ML, Lee CC, Tarantal AF, Byrne BJ.

Hum Gene Ther Clin Dev. 2016 Dec;27(4):152-159.

PMID:
27855487
14.

Molecular inotropy mediated by cardiac miR-based PDE4D/PRKAR1α/phosphoprotein signaling.

Bedada FB, Martindale JJ, Arden E, Metzger JM.

Sci Rep. 2016 Nov 11;6:36803. doi: 10.1038/srep36803.

15.

Adeno-Associated Virus 5 Transduces Adipose-Derived Stem Cells with Greater Efficacy Than Other Adeno-Associated Viral Serotypes.

Sharma P, Wimalawansa SM, Gould GC, Johnson RM, Excoffon KJ.

Hum Gene Ther Methods. 2016 Dec;27(6):219-227.

PMID:
27820963
16.

Empty Capsids and Macrophage Inhibition/Depletion Increase rAAV Transgene Expression in Joints of Both Healthy and Arthritic Mice.

Aalbers CJ, Broekstra N, van Geldorp M, Kramer E, Ramiro S, Tak PP, Vervoordeldonk MJ, Finn JD.

Hum Gene Ther. 2016 Nov 2. [Epub ahead of print]

PMID:
27806641
17.

RNAi prevents and reverses phenotypes induced by mutant human ataxin-1.

Keiser MS, Monteys AM, Corbau R, Gonzalez-Alegre P, Davidson BL.

Ann Neurol. 2016 Nov;80(5):754-765. doi: 10.1002/ana.24789.

18.

High-Density Recombinant Adeno-Associated Viral Particles are Competent Vectors for In Vivo Transduction.

Wang Q, Firrman J, Wu Z, Pokiniewski KA, Valencia CA, Wang H, Wei H, Zhuang Z, Liu L, Wunder SL, Chin MP, Xu R, Diao Y, Dong B, Xiao W.

Hum Gene Ther. 2016 Dec;27(12):971-981. doi: 10.1089/hum.2016.055.

PMID:
27550145
19.

Optogenetic activation of melanin-concentrating hormone neurons increases non-rapid eye movement and rapid eye movement sleep during the night in rats.

Blanco-Centurion C, Liu M, Konadhode RP, Zhang X, Pelluru D, van den Pol AN, Shiromani PJ.

Eur J Neurosci. 2016 Nov;44(10):2846-2857. doi: 10.1111/ejn.13410.

PMID:
27657541
20.

Intrathecal administration of AAV/GALC vectors in 10-11-day-old twitcher mice improves survival and is enhanced by bone marrow transplant.

Karumuthil-Melethil S, Marshall MS, Heindel C, Jakubauskas B, Bongarzone ER, Gray SJ.

J Neurosci Res. 2016 Nov;94(11):1138-51. doi: 10.1002/jnr.23882.

PMID:
27638599
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