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Transient pausing by RNA polymerase II.

Price DH.

Proc Natl Acad Sci U S A. 2018 May 8;115(19):4810-4812. doi: 10.1073/pnas.1805129115. Epub 2018 Apr 24. No abstract available.


Hydrogen peroxide yields mechanistic insights into human mRNA capping enzyme function.

Mullen NJ, Price DH.

PLoS One. 2017 Oct 13;12(10):e0186423. doi: 10.1371/journal.pone.0186423. eCollection 2017.


Oxidative stress rapidly stabilizes promoter-proximal paused Pol II across the human genome.

Nilson KA, Lawson CK, Mullen NJ, Ball CB, Spector BM, Meier JL, Price DH.

Nucleic Acids Res. 2017 Nov 2;45(19):11088-11105. doi: 10.1093/nar/gkx724.


Reconstitution of a functional 7SK snRNP.

Brogie JE, Price DH.

Nucleic Acids Res. 2017 Jun 20;45(11):6864-6880. doi: 10.1093/nar/gkx262.


Benzotriazoles Reactivate Latent HIV-1 through Inactivation of STAT5 SUMOylation.

Bosque A, Nilson KA, Macedo AB, Spivak AM, Archin NM, Van Wagoner RM, Martins LJ, Novis CL, Szaniawski MA, Ireland CM, Margolis DM, Price DH, Planelles V.

Cell Rep. 2017 Jan 31;18(5):1324-1334. doi: 10.1016/j.celrep.2017.01.022.


Stress from Nucleotide Depletion Activates the Transcriptional Regulator HEXIM1 to Suppress Melanoma.

Tan JL, Fogley RD, Flynn RA, Ablain J, Yang S, Saint-André V, Fan ZP, Do BT, Laga AC, Fujinaga K, Santoriello C, Greer CB, Kim YJ, Clohessy JG, Bothmer A, Pandell N, Avagyan S, Brogie JE, van Rooijen E, Hagedorn EJ, Shyh-Chang N, White RM, Price DH, Pandolfi PP, Peterlin BM, Zhou Y, Kim TH, Asara JM, Chang HY, Young RA, Zon LI.

Mol Cell. 2016 Apr 7;62(1):34-46. doi: 10.1016/j.molcel.2016.03.013.


THZ1 Reveals Roles for Cdk7 in Co-transcriptional Capping and Pausing.

Nilson KA, Guo J, Turek ME, Brogie JE, Delaney E, Luse DS, Price DH.

Mol Cell. 2015 Aug 20;59(4):576-87. doi: 10.1016/j.molcel.2015.06.032. Epub 2015 Aug 6.


Correction: Regulation of MYC Expression and Differential JQ1 Sensitivity in Cancer Cells.

Fowler T, Ghatak P, Price DH, Conaway R, Conaway J, Chiang CM, Bradner JE, Shilatifard A, Roy AL.

PLoS One. 2015 Apr 22;10(4):e0126328. doi: 10.1371/journal.pone.0126328. eCollection 2015. No abstract available.


Sequence specificity incompletely defines the genome-wide occupancy of Myc.

Guo J, Li T, Schipper J, Nilson KA, Fordjour FK, Cooper JJ, Gordân R, Price DH.

Genome Biol. 2014;15(10):482.


Crystal structure of HIV-1 Tat complexed with human P-TEFb and AFF4.

Gu J, Babayeva ND, Suwa Y, Baranovskiy AG, Price DH, Tahirov TH.

Cell Cycle. 2014;13(11):1788-97. doi: 10.4161/cc.28756. Epub 2014 Apr 11.


Regulation of RNA polymerase II termination by phosphorylation of Gdown1.

Guo J, Turek ME, Price DH.

J Biol Chem. 2014 May 2;289(18):12657-65. doi: 10.1074/jbc.M113.537662. Epub 2014 Mar 14.


Functional interactions of the RNA polymerase II-interacting proteins Gdown1 and TFIIF.

Mullen Davis MA, Guo J, Price DH, Luse DS.

J Biol Chem. 2014 Apr 18;289(16):11143-52. doi: 10.1074/jbc.M113.544395. Epub 2014 Mar 4.


Release of positive transcription elongation factor b (P-TEFb) from 7SK small nuclear ribonucleoprotein (snRNP) activates hexamethylene bisacetamide-inducible protein (HEXIM1) transcription.

Liu P, Xiang Y, Fujinaga K, Bartholomeeusen K, Nilson KA, Price DH, Peterlin BM.

J Biol Chem. 2014 Apr 4;289(14):9918-25. doi: 10.1074/jbc.M113.539015. Epub 2014 Feb 10.


Regulation of MYC expression and differential JQ1 sensitivity in cancer cells.

Fowler T, Ghatak P, Price DH, Conaway R, Conaway J, Chiang CM, Bradner JE, Shilatifard A, Roy AL.

PLoS One. 2014 Jan 23;9(1):e87003. doi: 10.1371/journal.pone.0087003. eCollection 2014. Erratum in: PLoS One. 2015;10(4):e0126328.


Runaway transcription.

Guo J, Li T, Price DH.

Genome Biol. 2013;14(9):133.


RNA polymerase II transcription elongation control.

Guo J, Price DH.

Chem Rev. 2013 Nov 13;113(11):8583-603. doi: 10.1021/cr400105n. Epub 2013 Aug 6. Review. No abstract available.


Effect of mimetic CDK9 inhibitors on HIV-1-activated transcription.

Van Duyne R, Guendel I, Jaworski E, Sampey G, Klase Z, Chen H, Zeng C, Kovalskyy D, El Kouni MH, Lepene B, Patanarut A, Nekhai S, Price DH, Kashanchi F.

J Mol Biol. 2013 Feb 22;425(4):812-29. doi: 10.1016/j.jmb.2012.12.005. Epub 2012 Dec 13.


Transcriptional regulation of the GPX1 gene by TFAP2C and aberrant CpG methylation in human breast cancer.

Kulak MV, Cyr AR, Woodfield GW, Bogachek M, Spanheimer PM, Li T, Price DH, Domann FE, Weigel RJ.

Oncogene. 2013 Aug 22;32(34):4043-51. doi: 10.1038/onc.2012.400. Epub 2012 Sep 10.


PKC phosphorylates HEXIM1 and regulates P-TEFb activity.

Fujinaga K, Barboric M, Li Q, Luo Z, Price DH, Peterlin BM.

Nucleic Acids Res. 2012 Oct;40(18):9160-70. doi: 10.1093/nar/gks682. Epub 2012 Jul 20.


RNA polymerase II elongation control.

Zhou Q, Li T, Price DH.

Annu Rev Biochem. 2012;81:119-43. doi: 10.1146/annurev-biochem-052610-095910. Epub 2012 Mar 9. Review.

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