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Items: 1 to 20 of 41


Immune Checkpoint Blockade Restores HIV-Specific CD4 T Cell Help for NK Cells.

Porichis F, Hart MG, Massa A, Everett HL, Morou A, Richard J, Brassard N, Veillette M, Hassan M, Ly NL, Routy JP, Freeman GJ, Dubé M, Finzi A, Kaufmann DE.

J Immunol. 2018 Aug 1;201(3):971-981. doi: 10.4049/jimmunol.1701551. Epub 2018 Jun 22.


FISHing Out the Hidden Enemy: Advances in Detecting and Measuring Latent HIV-Infected Cells.

Prasad VR, Kalpana GV.

MBio. 2017 Sep 19;8(5). pii: e01433-17. doi: 10.1128/mBio.01433-17.


Multiparametric characterization of rare HIV-infected cells using an RNA-flow FISH technique.

Baxter AE, Niessl J, Fromentin R, Richard J, Porichis F, Massanella M, Brassard N, Alsahafi N, Routy JP, Finzi A, Chomont N, Kaufmann DE.

Nat Protoc. 2017 Oct;12(10):2029-2049. doi: 10.1038/nprot.2017.079. Epub 2017 Sep 7.


Sporting Activity Is Reduced 11 Years After First-Generation Autologous Chondrocyte Implantation in the Knee Joint.

Erdle B, Herrmann S, Porichis S, Uhl M, Ghanem N, Schmal H, Suedkamp N, Niemeyer P, Salzmann GM.

Am J Sports Med. 2017 Oct;45(12):2762-2773. doi: 10.1177/0363546517716920. Epub 2017 Aug 8.


Circulating CXCR5+CXCR3+PD-1lo Tfh-like cells in HIV-1 controllers with neutralizing antibody breadth.

Martin-Gayo E, Cronin J, Hickman T, Ouyang Z, Lindqvist M, Kolb KE, Schulze Zur Wiesch J, Cubas R, Porichis F, Shalek AK, van Lunzen J, Haddad EK, Walker BD, Kaufmann DE, Lichterfeld M, Yu XG.

JCI Insight. 2017 Jan 26;2(2):e89574. doi: 10.1172/jci.insight.89574.


HIV Controllers Exhibit Enhanced Frequencies of Major Histocompatibility Complex Class II Tetramer+ Gag-Specific CD4+ T Cells in Chronic Clade C HIV-1 Infection.

Laher F, Ranasinghe S, Porichis F, Mewalal N, Pretorius K, Ismail N, Buus S, Stryhn A, Carrington M, Walker BD, Ndung'u T, Ndhlovu ZM.

J Virol. 2017 Mar 13;91(7). pii: e02477-16. doi: 10.1128/JVI.02477-16. Print 2017 Apr 1.


Increased frequencies of CD8+CD57+ T cells are associated with antibody neutralization breadth against HIV in viraemic controllers.

Palmer CD, Romero-Tejeda M, Scully EP, Lockhart A, Seaman MS, Goldenthal A, Piechocka-Trocha A, Walker BD, Chibnik LB, Jost S, Porichis F.

J Int AIDS Soc. 2016 Dec 9;19(1):21136. doi: 10.7448/IAS.19.1.21136. eCollection 2016.


Single-Cell Characterization of Viral Translation-Competent Reservoirs in HIV-Infected Individuals.

Baxter AE, Niessl J, Fromentin R, Richard J, Porichis F, Charlebois R, Massanella M, Brassard N, Alsahafi N, Delgado GG, Routy JP, Walker BD, Finzi A, Chomont N, Kaufmann DE.

Cell Host Microbe. 2016 Sep 14;20(3):368-380. doi: 10.1016/j.chom.2016.07.015. Epub 2016 Aug 18.


Elite controller CD8+ T cells exhibit comparable viral inhibition capacity, but better sustained effector properties compared to chronic progressors.

Shasha D, Karel D, Angiuli O, Greenblatt A, Ghebremichael M, Yu X, Porichis F, Walker BD.

J Leukoc Biol. 2016 Dec;100(6):1425-1433. Epub 2016 Jul 12.


Return to Sports Activity and Work After Autologous Chondrocyte Implantation of the Knee: Which Factors Influence Outcomes?

Pestka JM, Feucht MJ, Porichis S, Bode G, Südkamp NP, Niemeyer P.

Am J Sports Med. 2016 Feb;44(2):370-7. doi: 10.1177/0363546515614578. Epub 2015 Dec 9.


HIV-1 Antibody Neutralization Breadth Is Associated with Enhanced HIV-Specific CD4+ T Cell Responses.

Ranasinghe S, Soghoian DZ, Lindqvist M, Ghebremichael M, Donaghey F, Carrington M, Seaman MS, Kaufmann DE, Walker BD, Porichis F.

J Virol. 2015 Dec 9;90(5):2208-20. doi: 10.1128/JVI.02278-15.


Sex Differences in Plasmacytoid Dendritic Cell Levels of IRF5 Drive Higher IFN-α Production in Women.

Griesbeck M, Ziegler S, Laffont S, Smith N, Chauveau L, Tomezsko P, Sharei A, Kourjian G, Porichis F, Hart M, Palmer CD, Sirignano M, Beisel C, Hildebrandt H, Cénac C, Villani AC, Diefenbach TJ, Le Gall S, Schwartz O, Herbeuval JP, Autran B, Guéry JC, Chang JJ, Altfeld M.

J Immunol. 2015 Dec 1;195(11):5327-36. doi: 10.4049/jimmunol.1501684. Epub 2015 Oct 30.


Immunization of HIV-1-Infected Persons With Autologous Dendritic Cells Transfected With mRNA Encoding HIV-1 Gag and Nef: Results of a Randomized, Placebo-Controlled Clinical Trial.

Gandhi RT, Kwon DS, Macklin EA, Shopis JR, McLean AP, McBrine N, Flynn T, Peter L, Sbrolla A, Kaufmann DE, Porichis F, Walker BD, Bhardwaj N, Barouch DH, Kavanagh DG.

J Acquir Immune Defic Syndr. 2016 Mar 1;71(3):246-53. doi: 10.1097/QAI.0000000000000852.


Co-infection with Mycobacterium tuberculosis impairs HIV-Specific CD8+ and CD4+ T cell functionality.

Chetty S, Govender P, Zupkosky J, Pillay M, Ghebremichael M, Moosa MY, Ndung'u T, Porichis F, Kasprowicz VO.

PLoS One. 2015 Mar 17;10(3):e0118654. doi: 10.1371/journal.pone.0118654. eCollection 2015. Erratum in: PLoS One. 2015 May 20;10 (5):e0127763.


High-throughput detection of miRNAs and gene-specific mRNA at the single-cell level by flow cytometry.

Porichis F, Hart MG, Griesbeck M, Everett HL, Hassan M, Baxter AE, Lindqvist M, Miller SM, Soghoian DZ, Kavanagh DG, Reynolds S, Norris B, Mordecai SK, Nguyen Q, Lai C, Kaufmann DE.

Nat Commun. 2014 Dec 4;5:5641. doi: 10.1038/ncomms6641.


Tuberculosis distorts the inhibitory impact of interleukin-10 in HIV infection.

Chetty S, Porichis F, Govender P, Zupkosky J, Ghebremichael M, Pillay M, Walker BD, Ndung'u T, Kaufmann DE, Kasprowicz VO.

AIDS. 2014 Nov 28;28(18):2671-6. doi: 10.1097/QAD.0000000000000437.


Long-term T2 and Qualitative MRI Morphology After First-Generation Knee Autologous Chondrocyte Implantation: Cartilage Ultrastructure Is Not Correlated to Clinical or Qualitative MRI Outcome.

Salzmann GM, Erdle B, Porichis S, Uhl M, Ghanem N, Schmal H, Kubosch D, Südkamp NP, Niemeyer P.

Am J Sports Med. 2014 Aug;42(8):1832-40. doi: 10.1177/0363546514536682. Epub 2014 Jun 16.


First-generation versus second-generation autologous chondrocyte implantation for treatment of cartilage defects of the knee: a matched-pair analysis on long-term clinical outcome.

Niemeyer P, Salzmann G, Feucht M, Pestka J, Porichis S, Ogon P, Südkamp N, Schmal H.

Int Orthop. 2014 Oct;38(10):2065-70. doi: 10.1007/s00264-014-2368-0. Epub 2014 May 17.


Differential impact of PD-1 and/or interleukin-10 blockade on HIV-1-specific CD4 T cell and antigen-presenting cell functions.

Porichis F, Hart MG, Zupkosky J, Barblu L, Kwon DS, McMullen A, Brennan T, Ahmed R, Freeman GJ, Kavanagh DG, Kaufmann DE.

J Virol. 2014 Mar;88(5):2508-18. doi: 10.1128/JVI.02034-13. Epub 2013 Dec 18.


In vitro assay to evaluate the impact of immunoregulatory pathways on HIV-specific CD4 T cell effector function.

Porichis F, Hart MG, Zupkosky J, Barblu L, Kaufmann DE.

J Vis Exp. 2013 Oct 15;(80):e50821. doi: 10.3791/50821.

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