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[Polyoxyl 40 stearate].
De Santis A, Fabris L, Fontani F, Taccani F, Zorzetto C. De Santis A, et al. Boll Chim Farm. 1970 Sep;109(9):503. Boll Chim Farm. 1970. PMID: 5499459 Italian. No abstract available.
In-silico approach as a tool for selection of excipients for safer amphotericin B nanoformulations.
Todke PA, Devarajan PV. Todke PA, et al. J Control Release. 2022 Sep;349:756-764. doi: 10.1016/j.jconrel.2022.07.030. Epub 2022 Aug 1. J Control Release. 2022. PMID: 35905782
Excipients selected for the study included linear fatty acids from caprylic (C(8)) to stearic(C(18)) and the stearate based amphiphilic surfactants polyoxyl-15-hydroxystearate (PS15) and polyoxyl-40-stearate (PS40). ...
Excipients selected for the study included linear fatty acids from caprylic (C(8)) to stearic(C(18)) and the stearate based amphiphil …
Nonionic surfactants are strong inhibitors of cytochrome P450 3A biotransformation activity in vitro and in vivo.
Ren X, Mao X, Cao L, Xue K, Si L, Qiu J, Schimmer AD, Li G. Ren X, et al. Eur J Pharm Sci. 2009 Mar 2;36(4-5):401-11. doi: 10.1016/j.ejps.2008.11.002. Epub 2008 Nov 8. Eur J Pharm Sci. 2009. PMID: 19041719
Here, we examined the effects of four common nonionic surfactants polysorbate 20, polyoxyl 35 castor oil, polyoxyl 40 stearate and poloxamer 188, on cytochrome P450 3A in vitro and in vivo using midazolam as a probe. ...Polyoxyl 35 castor oil, …
Here, we examined the effects of four common nonionic surfactants polysorbate 20, polyoxyl 35 castor oil, polyoxyl 40 …
Nanostructured lipid carriers for incorporation of copper(II) complexes to be used against Mycobacterium tuberculosis.
Sato MR, Oshiro Junior JA, Machado RT, de Souza PC, Campos DL, Pavan FR, da Silva PB, Chorilli M. Sato MR, et al. Drug Des Devel Ther. 2017 Mar 20;11:909-921. doi: 10.2147/DDDT.S127048. eCollection 2017. Drug Des Devel Ther. 2017. PMID: 28356717 Free PMC article.
The NLCs comprised the following lipid phase: 2.07% polyoxyethylene 40 stearate, 2.05% caprylic/capric triglyceride, and 0.88% polyoxyl 40 hydrogenated castor oil; the following aqueous phase: 3.50% poloxamer 407 (F1-F6), and 0.50% cetyltrimethylammoni …
The NLCs comprised the following lipid phase: 2.07% polyoxyethylene 40 stearate, 2.05% caprylic/capric triglyceride, and 0.88% …
Development and evaluation of dexamethasone nanomicelles with potential for treating posterior uveitis after topical application.
Patel S, Garapati C, Chowdhury P, Gupta H, Nesamony J, Nauli S, Boddu SH. Patel S, et al. J Ocul Pharmacol Ther. 2015 May;31(4):215-27. doi: 10.1089/jop.2014.0152. Epub 2015 Apr 3. J Ocul Pharmacol Ther. 2015. PMID: 25839185
PURPOSE: This study aims at the development and preliminary evaluation of dexamethasone nanomicelles for treating posterior uveitis. Nanomicelles were formulated using polyoxyl 40 stearate (P40S) and polysorbate 80 (P80), which are approved by the FDA for ocu …
PURPOSE: This study aims at the development and preliminary evaluation of dexamethasone nanomicelles for treating posterior uveitis. Nanomic …
Effect of surfactants or a water soluble polymer on the crystal transition of clarithromycin during a wet granulation process.
Nozawa K, Iwao Y, Noguchi S, Itai S. Nozawa K, et al. Int J Pharm. 2015 Nov 10;495(1):204-217. doi: 10.1016/j.ijpharm.2015.08.080. Epub 2015 Sep 7. Int J Pharm. 2015. PMID: 26325306
Form I was completely converted to form II by a wet granulation using water with additives bearing polyoxyethylene chains such as polysorbate 80 (PS80), polyoxyl 40 stearate or macrogol 400. The granulation of the form II using ethanol with these additives di …
Form I was completely converted to form II by a wet granulation using water with additives bearing polyoxyethylene chains such as polysorbat …
New microemulsion vehicle facilitates percutaneous penetration in vitro and cutaneous drug bioavailability in vivo.
Sintov AC, Shapiro L. Sintov AC, et al. J Control Release. 2004 Mar 5;95(2):173-83. doi: 10.1016/j.jconrel.2003.11.004. J Control Release. 2004. PMID: 14980766
The existence of microemulsion regions was investigated in quaternary systems composed of glyceryl oleate+polyoxyl 40 fatty acid derivatives (surfactants)/tetraglycol (co-surfactant)/isopropyl palmitate/water by constructing pseudo-ternary phase diagrams at fixed co …
The existence of microemulsion regions was investigated in quaternary systems composed of glyceryl oleate+polyoxyl 40 fatty ac …
In vitro and in vivo studies evaluating antisemen antibodies as a potential spermicidal agent in hamsters.
Chen DY, Liu LM, Xie QD, Xu L, Huang TH. Chen DY, et al. Fertil Steril. 2009 Sep;92(3):1116-1123. doi: 10.1016/j.fertnstert.2008.07.1748. Epub 2008 Oct 4. Fertil Steril. 2009. PMID: 18835604 Free article.
None of the four hamsters that received antisemen antibodies in gel-polyoxyl-40-stearate had epithelial disruption characteristic of inflammation. ...
None of the four hamsters that received antisemen antibodies in gel-polyoxyl-40-stearate had epithelial disruption char …