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Items: 20

1.

Stereoselective Deuteration in Aspartate, Asparagine, Lysine, and Methionine Amino Acid Residues Using Fumarate as a Carbon Source for Escherichia coli in D2O.

Danmaliki GI, Liu PB, Hwang PM.

Biochemistry. 2017 Nov 14;56(45):6015-6029. doi: 10.1021/acs.biochem.7b00991. Epub 2017 Nov 3.

PMID:
29068222
2.

Structures reveal details of small molecule binding to cardiac troponin.

Cai F, Li MX, Pineda-Sanabria SE, Gelozia S, Lindert S, West F, Sykes BD, Hwang PM.

J Mol Cell Cardiol. 2016 Dec;101:134-144. doi: 10.1016/j.yjmcc.2016.10.016. Epub 2016 Nov 5. Review.

3.

'(De-)sensitization' vs. 'Uncoupling': what drives cardiomyopathies in the thin filament?

Hwang PM.

Cardiovasc Res. 2016 Jan 1;109(1):185-6. doi: 10.1093/cvr/cvv232. Epub 2015 Oct 12. No abstract available.

PMID:
26464330
4.

Combining a PagP fusion protein system with nickel ion-catalyzed cleavage to produce intrinsically disordered proteins in E. coli.

Zahran S, Pan JS, Liu PB, Hwang PM.

Protein Expr Purif. 2015 Dec;116:133-8. doi: 10.1016/j.pep.2015.08.018. Epub 2015 Aug 19.

PMID:
26297994
5.

Structure and function of cardiac troponin C (TNNC1): Implications for heart failure, cardiomyopathies, and troponin modulating drugs.

Li MX, Hwang PM.

Gene. 2015 Oct 25;571(2):153-66. doi: 10.1016/j.gene.2015.07.074. Epub 2015 Jul 29. Review.

6.

Targeting the sarcomere to correct muscle function.

Hwang PM, Sykes BD.

Nat Rev Drug Discov. 2015 May;14(5):313-28. doi: 10.1038/nrd4554. Epub 2015 Apr 17. Review.

PMID:
25881969
7.

The cardiac-specific N-terminal region of troponin I positions the regulatory domain of troponin C.

Hwang PM, Cai F, Pineda-Sanabria SE, Corson DC, Sykes BD.

Proc Natl Acad Sci U S A. 2014 Oct 7;111(40):14412-7. doi: 10.1073/pnas.1410775111. Epub 2014 Sep 22.

8.

Targeted expression, purification, and cleavage of fusion proteins from inclusion bodies in Escherichia coli.

Hwang PM, Pan JS, Sykes BD.

FEBS Lett. 2014 Jan 21;588(2):247-52. doi: 10.1016/j.febslet.2013.09.028. Epub 2013 Sep 27. Review.

9.

A PagP fusion protein system for the expression of intrinsically disordered proteins in Escherichia coli.

Hwang PM, Pan JS, Sykes BD.

Protein Expr Purif. 2012 Sep;85(1):148-51. doi: 10.1016/j.pep.2012.07.007. Epub 2012 Jul 25.

PMID:
22841980
10.

Topology of an outer-membrane enzyme: Measuring oxygen and water contacts in solution NMR studies of PagP.

Evanics F, Hwang PM, Cheng Y, Kay LE, Prosser RS.

J Am Chem Soc. 2006 Jun 28;128(25):8256-64.

PMID:
16787090
11.

Quantitative NMR spectroscopy of supramolecular complexes: dynamic side pores in ClpP are important for product release.

Sprangers R, Gribun A, Hwang PM, Houry WA, Kay LE.

Proc Natl Acad Sci U S A. 2005 Nov 15;102(46):16678-83. Epub 2005 Nov 1.

12.
13.

A hydrocarbon ruler measures palmitate in the enzymatic acylation of endotoxin.

Ahn VE, Lo EI, Engel CK, Chen L, Hwang PM, Kay LE, Bishop RE, Privé GG.

EMBO J. 2004 Aug 4;23(15):2931-41. Epub 2004 Jul 22.

14.

The integral membrane enzyme PagP alternates between two dynamically distinct states.

Hwang PM, Bishop RE, Kay LE.

Proc Natl Acad Sci U S A. 2004 Jun 29;101(26):9618-23. Epub 2004 Jun 21.

15.

Nuclear magnetic resonance spectroscopy of high-molecular-weight proteins.

Tugarinov V, Hwang PM, Kay LE.

Annu Rev Biochem. 2004;73:107-46. Review.

PMID:
15189138
16.
17.

Solution structure and dynamics of the outer membrane enzyme PagP by NMR.

Hwang PM, Choy WY, Lo EI, Chen L, Forman-Kay JD, Raetz CR, Privé GG, Bishop RE, Kay LE.

Proc Natl Acad Sci U S A. 2002 Oct 15;99(21):13560-5. Epub 2002 Sep 30.

18.

Solution structures of the cytoplasmic tail complex from platelet integrin alpha IIb- and beta 3-subunits.

Weljie AM, Hwang PM, Vogel HJ.

Proc Natl Acad Sci U S A. 2002 Apr 30;99(9):5878-83.

20.

A "three-pronged" binding mechanism for the SAP/SH2D1A SH2 domain: structural basis and relevance to the XLP syndrome.

Hwang PM, Li C, Morra M, Lillywhite J, Muhandiram DR, Gertler F, Terhorst C, Kay LE, Pawson T, Forman-Kay JD, Li SC.

EMBO J. 2002 Feb 1;21(3):314-23.

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