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Items: 1 to 20 of 36


Comparative transcriptomic analyses and single-cell RNA sequencing of the freshwater planarian Schmidtea mediterranea identify major cell types and pathway conservation.

Swapna LS, Molinaro AM, Lindsay-Mosher N, Pearson BJ, Parkinson J.

Genome Biol. 2018 Aug 24;19(1):124. doi: 10.1186/s13059-018-1498-x.


The true colours of the flatworm: Mechanisms of pigment biosynthesis and pigment cell lineage development in planarians.

Lindsay-Mosher N, Pearson BJ.

Semin Cell Dev Biol. 2018 May 21. pii: S1084-9521(17)30194-5. doi: 10.1016/j.semcdb.2018.05.010. [Epub ahead of print] Review.


The planarian TCF/LEF factor Smed-tcf1 is required for the regeneration of dorsal-lateral neuronal subtypes.

Brown DDR, Molinaro AM, Pearson BJ.

Dev Biol. 2018 Jan 15;433(2):374-383. doi: 10.1016/j.ydbio.2017.08.024. Epub 2017 Dec 25.


FOX and ETS family transcription factors regulate the pigment cell lineage in planarians.

He X, Lindsay-Mosher N, Li Y, Molinaro AM, Pellettieri J, Pearson BJ.

Development. 2017 Dec 15;144(24):4540-4551. doi: 10.1242/dev.156349. Epub 2017 Nov 20.


Yorkie is required to restrict the injury responses in planarians.

Lin AYT, Pearson BJ.

PLoS Genet. 2017 Jul 7;13(7):e1006874. doi: 10.1371/journal.pgen.1006874. eCollection 2017 Jul.


A Brain Unfixed: Unlimited Neurogenesis and Regeneration of the Adult Planarian Nervous System.

Brown DDR, Pearson BJ.

Front Neurosci. 2017 May 23;11:289. doi: 10.3389/fnins.2017.00289. eCollection 2017.


Nervous system development and regeneration in freshwater planarians.

Ross KG, Currie KW, Pearson BJ, Zayas RM.

Wiley Interdiscip Rev Dev Biol. 2017 May;6(3). doi: 10.1002/wdev.266. Epub 2017 Mar 22. Review.


Neuronal sources of hedgehog modulate neurogenesis in the adult planarian brain.

Currie KW, Molinaro AM, Pearson BJ.

Elife. 2016 Nov 19;5. pii: e19735. doi: 10.7554/eLife.19735.


(Neo)blast from the past: new insights into planarian stem cell lineages.

Zhu SJ, Pearson BJ.

Curr Opin Genet Dev. 2016 Oct;40:74-80. doi: 10.1016/j.gde.2016.06.007. Epub 2016 Jul 2. Review.


Light-induced depigmentation in planarians models the pathophysiology of acute porphyrias.

Stubenhaus BM, Dustin JP, Neverett ER, Beaudry MS, Nadeau LE, Burk-McCoy E, He X, Pearson BJ, Pellettieri J.

Elife. 2016 May 31;5. pii: e14175. doi: 10.7554/eLife.14175.


In silico lineage tracing through single cell transcriptomics identifies a neural stem cell population in planarians.

Molinaro AM, Pearson BJ.

Genome Biol. 2016 Apr 27;17:87. doi: 10.1186/s13059-016-0937-9.


HOX gene complement and expression in the planarian Schmidtea mediterranea.

Currie KW, Brown DD, Zhu S, Xu C, Voisin V, Bader GD, Pearson BJ.

Evodevo. 2016 Mar 30;7:7. doi: 10.1186/s13227-016-0044-8. eCollection 2016.


A mex3 homolog is required for differentiation during planarian stem cell lineage development.

Zhu SJ, Hallows SE, Currie KW, Xu C, Pearson BJ.

Elife. 2015 Jun 26;4. doi: 10.7554/eLife.07025.


An in vivo requirement for the mediator subunit med14 in the maintenance of stem cell populations.

Burrows JT, Pearson BJ, Scott IC.

Stem Cell Reports. 2015 Apr 14;4(4):670-84. doi: 10.1016/j.stemcr.2015.02.006. Epub 2015 Mar 12.


Smed-dynA-1 is a planarian nervous system specific dynamin 1 homolog required for normal locomotion.

Talbot JA, Currie KW, Pearson BJ, Collins EM.

Biol Open. 2014 Jun 20;3(7):627-34. doi: 10.1242/bio.20147583.


Planarian yorkie/YAP functions to integrate adult stem cell proliferation, organ homeostasis and maintenance of axial patterning.

Lin AY, Pearson BJ.

Development. 2014 Mar;141(6):1197-208. doi: 10.1242/dev.101915. Epub 2014 Feb 12.


Genome-wide analysis of the bHLH gene family in planarians identifies factors required for adult neurogenesis and neuronal regeneration.

Cowles MW, Brown DD, Nisperos SV, Stanley BN, Pearson BJ, Zayas RM.

Development. 2013 Dec;140(23):4691-702. doi: 10.1242/dev.098616. Epub 2013 Oct 30.


Transcription factors lhx1/5-1 and pitx are required for the maintenance and regeneration of serotonergic neurons in planarians.

Currie KW, Pearson BJ.

Development. 2013 Sep;140(17):3577-88. doi: 10.1242/dev.098590. Epub 2013 Jul 31.


The Retinoblastoma pathway regulates stem cell proliferation in freshwater planarians.

Zhu SJ, Pearson BJ.

Dev Biol. 2013 Jan 15;373(2):442-52. doi: 10.1016/j.ydbio.2012.10.025. Epub 2012 Nov 1.


A comparative transcriptomic analysis reveals conserved features of stem cell pluripotency in planarians and mammals.

Labbé RM, Irimia M, Currie KW, Lin A, Zhu SJ, Brown DD, Ross EJ, Voisin V, Bader GD, Blencowe BJ, Pearson BJ.

Stem Cells. 2012 Aug;30(8):1734-45. doi: 10.1002/stem.1144.

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