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Items: 1 to 20 of 70

1.

Molecular Characterization of Human Lymph Node Stromal Cells During the Earliest Phases of Rheumatoid Arthritis.

Karouzakis E, Hähnlein J, Grasso C, Semmelink JF, Tak PP, Gerlag DM, Gay S, Ospelt C, van Baarsen LGM.

Front Immunol. 2019 Aug 20;10:1863. doi: 10.3389/fimmu.2019.01863. eCollection 2019.

2.

Anticitrullinated protein antibodies facilitate migration of synovial tissue-derived fibroblasts.

Sun M, Rethi B, Krishnamurthy A, Joshua V, Circiumaru A, Hensvold AH, Ossipova E, Grönwall C, Liu Y, Engstrom M, Catrina SB, Steen J, Malmstrom V, Klareskog L, Svensson C, Ospelt C, Wähämaa H, Catrina AI.

Ann Rheum Dis. 2019 Dec;78(12):1621-1631. doi: 10.1136/annrheumdis-2018-214967. Epub 2019 Sep 3.

3.

Endogenous Galectin-9 Suppresses Apoptosis in Human Rheumatoid Arthritis Synovial Fibroblasts.

Pearson MJ, Bik MA, Ospelt C, Naylor AJ, Wehmeyer C, Jones SW, Buckley CD, Gay S, Filer A, Lord JM.

Sci Rep. 2018 Aug 27;8(1):12887. doi: 10.1038/s41598-018-31173-3.

4.

Evaluating the bromodomain protein BRD1 as a therapeutic target in rheumatoid arthritis.

Klein K, Kato M, Frank-Bertoncelj M, Kolling C, Ciurea A, Gay S, Ospelt C.

Sci Rep. 2018 Jul 24;8(1):11125. doi: 10.1038/s41598-018-29127-w.

5.

Analysis of early changes in DNA methylation in synovial fibroblasts of RA patients before diagnosis.

Karouzakis E, Raza K, Kolling C, Buckley CD, Gay S, Filer A, Ospelt C.

Sci Rep. 2018 May 9;8(1):7370. doi: 10.1038/s41598-018-24240-2.

6.

CARD14 Gain-of-Function Mutation Alone Is Sufficient to Drive IL-23/IL-17-Mediated Psoriasiform Skin Inflammation In Vivo.

Mellett M, Meier B, Mohanan D, Schairer R, Cheng P, Satoh TK, Kiefer B, Ospelt C, Nobbe S, Thome M, Contassot E, French LE.

J Invest Dermatol. 2018 Sep;138(9):2010-2023. doi: 10.1016/j.jid.2018.03.1525. Epub 2018 Apr 22.

7.

The p55TNFR-IKK2-Ripk3 axis orchestrates arthritis by regulating death and inflammatory pathways in synovial fibroblasts.

Armaka M, Ospelt C, Pasparakis M, Kollias G.

Nat Commun. 2018 Feb 12;9(1):618. doi: 10.1038/s41467-018-02935-4.

8.

Synovial fibroblasts in 2017.

Ospelt C.

RMD Open. 2017 Oct 15;3(2):e000471. doi: 10.1136/rmdopen-2017-000471. eCollection 2017. Review.

9.

The epigenetic architecture at gene promoters determines cell type-specific LPS tolerance.

Klein K, Frank-Bertoncelj M, Karouzakis E, Gay RE, Kolling C, Ciurea A, Bostanci N, Belibasakis GN, Lin LL, Distler O, Gay S, Ospelt C.

J Autoimmun. 2017 Sep;83:122-133. doi: 10.1016/j.jaut.2017.07.001. Epub 2017 Jul 9.

PMID:
28701277
10.

Why location matters - site-specific factors in rheumatic diseases.

Ospelt C, Frank-Bertoncelj M.

Nat Rev Rheumatol. 2017 Jul;13(7):433-442. doi: 10.1038/nrrheum.2017.96. Epub 2017 Jun 15. Review.

PMID:
28615733
11.

Comment on "Epigenetics in the pathogenesis of RA".

Gomez-Cabrero D, Tegnér J, Ekström TJ, Ospelt C.

Semin Immunopathol. 2017 Jun;39(4):421-422. doi: 10.1007/s00281-017-0638-9. Epub 2017 May 11. No abstract available.

PMID:
28497351
12.

Genomic Responses of Mouse Synovial Fibroblasts During Tumor Necrosis Factor-Driven Arthritogenesis Greatly Mimic Those in Human Rheumatoid Arthritis.

Ntougkos E, Chouvardas P, Roumelioti F, Ospelt C, Frank-Bertoncelj M, Filer A, Buckley CD, Gay S, Nikolaou C, Kollias G.

Arthritis Rheumatol. 2017 Aug;69(8):1588-1600. doi: 10.1002/art.40128. Epub 2017 Jul 5.

13.

Epigenetically-driven anatomical diversity of synovial fibroblasts guides joint-specific fibroblast functions.

Frank-Bertoncelj M, Trenkmann M, Klein K, Karouzakis E, Rehrauer H, Bratus A, Kolling C, Armaka M, Filer A, Michel BA, Gay RE, Buckley CD, Kollias G, Gay S, Ospelt C.

Nat Commun. 2017 Mar 23;8:14852. doi: 10.1038/ncomms14852.

14.

Epigenetics in the pathogenesis of RA.

Ospelt C, Gay S, Klein K.

Semin Immunopathol. 2017 Jun;39(4):409-419. doi: 10.1007/s00281-017-0621-5. Epub 2017 Mar 21. Review.

PMID:
28324153
15.

Carbamylation of vimentin is inducible by smoking and represents an independent autoantigen in rheumatoid arthritis.

Ospelt C, Bang H, Feist E, Camici G, Keller S, Detert J, Krämer A, Gay S, Ghannam K, Burmester GR.

Ann Rheum Dis. 2017 Jul;76(7):1176-1183. doi: 10.1136/annrheumdis-2016-210059. Epub 2017 Feb 9.

16.

Expression and Regulation of PIWIL-Proteins and PIWI-Interacting RNAs in Rheumatoid Arthritis.

Pleštilová L, Neidhart M, Russo G, Frank-Bertoncelj M, Ospelt C, Ciurea A, Kolling C, Gay RE, Michel BA, Vencovský J, Gay S, Jüngel A.

PLoS One. 2016 Nov 28;11(11):e0166920. doi: 10.1371/journal.pone.0166920. eCollection 2016.

17.

Capture Hi-C identifies a novel causal gene, IL20RA, in the pan-autoimmune genetic susceptibility region 6q23.

McGovern A, Schoenfelder S, Martin P, Massey J, Duffus K, Plant D, Yarwood A, Pratt AG, Anderson AE, Isaacs JD, Diboll J, Thalayasingam N, Ospelt C, Barton A, Worthington J, Fraser P, Eyre S, Orozco G.

Genome Biol. 2016 Nov 1;17(1):212.

18.

Social media use among young rheumatologists and basic scientists: results of an international survey by the Emerging EULAR Network (EMEUNET).

Nikiphorou E, Studenic P, Ammitzbøll CG, Canavan M, Jani M, Ospelt C, Berenbaum F; EMEUNET.

Ann Rheum Dis. 2017 Apr;76(4):712-715. doi: 10.1136/annrheumdis-2016-209718. Epub 2016 Oct 24.

PMID:
27797750
19.

AAA-ATPase p97 suppresses apoptotic and autophagy-associated cell death in rheumatoid arthritis synovial fibroblasts.

Kato M, Ospelt C, Kolling C, Shimizu T, Kono M, Yasuda S, Michel BA, Gay RE, Gay S, Klein K, Atsumi T.

Oncotarget. 2016 Sep 27;7(39):64221-64232. doi: 10.18632/oncotarget.11890.

20.

Epigenetics: New insights into site-specific variations in RA and OA.

Ospelt C, Frank-Bertoncelj M.

Nat Rev Rheumatol. 2016 Sep;12(9):506-7. doi: 10.1038/nrrheum.2016.133. Epub 2016 Aug 11. No abstract available.

PMID:
27511221

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