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Items: 8


Anthracyclines suppress pheochromocytoma cell characteristics, including metastasis, through inhibition of the hypoxia signaling pathway.

Pang Y, Yang C, Schovanek J, Wang H, Bullova P, Caisova V, Gupta G, Wolf KI, Semenza GL, Zhuang Z, Pacak K.

Oncotarget. 2017 Apr 4;8(14):22313-22324. doi: 10.18632/oncotarget.16224.


Hypoxia-inducible factors regulate pluripotency factor expression by ZNF217- and ALKBH5-mediated modulation of RNA methylation in breast cancer cells.

Zhang C, Zhi WI, Lu H, Samanta D, Chen I, Gabrielson E, Semenza GL.

Oncotarget. 2016 Oct 4;7(40):64527-64542. doi: 10.18632/oncotarget.11743.


PRDX2 and PRDX4 are negative regulators of hypoxia-inducible factors under conditions of prolonged hypoxia.

Luo W, Chen I, Chen Y, Alkam D, Wang Y, Semenza GL.

Oncotarget. 2016 Feb 9;7(6):6379-97. doi: 10.18632/oncotarget.7142.


Hypoxia-inducible factor 1 upregulation of both VEGF and ANGPTL4 is required to promote the angiogenic phenotype in uveal melanoma.

Hu K, Babapoor-Farrokhran S, Rodrigues M, Deshpande M, Puchner B, Kashiwabuchi F, Hassan SJ, Asnaghi L, Handa JT, Merbs S, Eberhart CG, Semenza GL, Montaner S, Sodhi A.

Oncotarget. 2016 Feb 16;7(7):7816-28. doi: 10.18632/oncotarget.6868.


HIF-1α and TAZ serve as reciprocal co-activators in human breast cancer cells.

Xiang L, Gilkes DM, Hu H, Luo W, Bullen JW, Liang H, Semenza GL.

Oncotarget. 2015 May 20;6(14):11768-78.


Hypoxia-inducible factor 1 mediates TAZ expression and nuclear localization to induce the breast cancer stem cell phenotype.

Xiang L, Gilkes DM, Hu H, Takano N, Luo W, Lu H, Bullen JW, Samanta D, Liang H, Semenza GL.

Oncotarget. 2014 Dec 30;5(24):12509-27.


Hypoxia-inducible factors enhance glutamate signaling in cancer cells.

Hu H, Takano N, Xiang L, Gilkes DM, Luo W, Semenza GL.

Oncotarget. 2014 Oct 15;5(19):8853-68.

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