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Items: 1 to 20 of 13149

1.

Sofalcone, a gastroprotective drug, covalently binds to KEAP1 to activate Nrf2 resulting in anti-colitic activity.

Kim W, Lee H, Kim S, Joo S, Jeong S, Yoo JW, Jung Y.

Eur J Pharmacol. 2019 Oct 12:172722. doi: 10.1016/j.ejphar.2019.172722. [Epub ahead of print]

PMID:
31614142
2.

In vitro Biotransformation of the Nrf2 activator Bardoxolone: Formation of an Epoxide Metabolite that Undergoes Two Novel Glutathione-Mediated Metabolic Pathways; Epoxide Reduction and Oxidative Elimination of Nitrile Moiety.

Kamel AM, Bowlin S, Anwar B, Reichard H, Argus J, Blair IA.

Chem Res Toxicol. 2019 Oct 15. doi: 10.1021/acs.chemrestox.9b00289. [Epub ahead of print]

PMID:
31613099
3.

Silibinin inhibits migration and invasion of breast cancer MDA-MB-231 cells through induction of mitochondrial fusion.

Si L, Fu J, Liu W, Hayashi T, Nie Y, Mizuno K, Hattori S, Fujisaki H, Onodera S, Ikejima T.

Mol Cell Biochem. 2019 Oct 14. doi: 10.1007/s11010-019-03640-6. [Epub ahead of print]

PMID:
31612353
4.

Sanbai Melon Seed Oil Exerts Its Protective Effects in a Diabetes Mellitus Model via the Akt/GSK-3β/Nrf2 Pathway.

Wang F, Xi Y, Liu W, Li J, Zhang Y, Jia M, He Q, Zhao H, Wang S.

J Diabetes Res. 2019 Sep 12;2019:5734723. doi: 10.1155/2019/5734723. eCollection 2019.

PMID:
31612149
5.

Hesperidin ameliorates bleomycin-induced experimental pulmonary fibrosis via inhibition of TGF-beta1/Smad3/AMPK and IkappaBalpha/NF-kappaB pathways.

Zhou Z, Kandhare AD, Kandhare AA, Bodhankar SL.

EXCLI J. 2019 Aug 29;18:723-745. doi: 10.17179/excli2019-1094. eCollection 2019.

PMID:
31611754
6.

Soybean β-conglycinin caused intestinal inflammation and oxidative damage in association with NF-κB, TOR and Nrf2 in juvenile grass carp (Ctenopharyngodon idella): Varying among different intestinal segments.

Duan XD, Jiang WD, Wu P, Liu Y, Jiang J, Tan BP, Yang QH, Kuang SY, Tang L, Zhou XQ, Feng L.

Fish Shellfish Immunol. 2019 Oct 11. pii: S1050-4648(19)30980-5. doi: 10.1016/j.fsi.2019.10.021. [Epub ahead of print]

PMID:
31610288
7.

PHLPP2 downregulation protects cardiomyocytes against hypoxia-induced injury through reinforcing Nrf2/ARE antioxidant signaling.

Jin A, Li B, Li W, Xiao D.

Chem Biol Interact. 2019 Oct 11:108848. doi: 10.1016/j.cbi.2019.108848. [Epub ahead of print]

PMID:
31610156
8.

Identification of lead-produced lipid hydroperoxides in human HepG2 cells and protection using rosmarinic and ascorbic acids with a reference to their regulatory roles on Nrf2-Keap1 antioxidant pathway.

Li Y, Darwish WS, Chen Z, Hui T, Wu Y, Hirotaka S, Chiba H, Hui SP.

Chem Biol Interact. 2019 Oct 11:108847. doi: 10.1016/j.cbi.2019.108847. [Epub ahead of print]

PMID:
31610155
9.

Development of a Cell-Permeable Cyclic Peptidyl Inhibitor against the Keap1-Nrf2 Interaction.

Salim H, Song J, Sahni A, Pei D.

J Org Chem. 2019 Oct 14. doi: 10.1021/acs.joc.9b02367. [Epub ahead of print]

PMID:
31609620
10.

NO /RUNX3/Kynurenine Metabolic Signaling Enhances Disease Aggressiveness in Pancreatic Cancer.

Wang L, Tang W, Yang S, He P, Wang J, Gaedcke J, Strobel P, Azizian A, Ried T, Gaida MM, Yfantis HG, Lee DH, Lal A, Van den Eynde BJ, Alexander HR, Ghadimi BM, Hanna N, Hussain SP.

Int J Cancer. 2019 Oct 14. doi: 10.1002/ijc.32733. [Epub ahead of print]

PMID:
31609478
11.

Therapeutic and biological activities of berberine: The involvement of Nrf2 signaling pathway.

Ashrafizadeh M, Fekri HS, Ahmadi Z, Farkhondeh T, Samarghandian S.

J Cell Biochem. 2019 Oct 14. doi: 10.1002/jcb.29392. [Epub ahead of print]

PMID:
31609017
12.

Knockdown of ALK7 inhibits high glucose-induced oxidative stress and apoptosis in retinal pigment epithelial cells.

Shi Q, Dong X, Zhang M, Cheng Y, Pei C.

Clin Exp Pharmacol Physiol. 2019 Oct 14. doi: 10.1111/1440-1681.13189. [Epub ahead of print]

PMID:
31608496
13.

Pathophysiological Mechanisms and Potential Therapeutic Targets in Intracerebral Hemorrhage.

Shao Z, Tu S, Shao A.

Front Pharmacol. 2019 Sep 19;10:1079. doi: 10.3389/fphar.2019.01079. eCollection 2019. Review.

PMID:
31607923
14.

Histone H3F3/H3.3 chaperone DAXX converts to modulate SQSTM1 phase condensation for NFE2L2 activation.

Yang Y, Valionyte E, Kelly J, Luo S.

Autophagy. 2019 Oct 14. doi: 10.1080/15548627.2019.1677323. [Epub ahead of print]

PMID:
31607206
15.

Loss of methionine sulfoxide reductases increases resistance to oxidative stress.

Lai L, Sun J, Tarafdar S, Liu C, Murphy E, Kim G, Levine RL.

Free Radic Biol Med. 2019 Oct 10. pii: S0891-5849(19)31342-5. doi: 10.1016/j.freeradbiomed.2019.10.006. [Epub ahead of print]

PMID:
31606431
16.

Neurotoxicity mediated by oxidative stress caused by titanium dioxide nanoparticles in human neuroblastoma (SH-SY5Y) cells.

Ferraro SA, Domingo MG, Etcheverrito A, Olmedo DG, Tasat DR.

J Trace Elem Med Biol. 2019 Sep 25:126413. doi: 10.1016/j.jtemb.2019.126413. [Epub ahead of print]

PMID:
31606305
17.

Antioxidants cinnamaldehyde and Galactomyces fermentation filtrate downregulate senescence marker CDKN2A/p16INK4A via NRF2 activation in keratinocytes.

Hashimoto-Hachiya A, Tsuji G, Furue M.

J Dermatol Sci. 2019 Oct;96(1):53-56. doi: 10.1016/j.jdermsci.2019.09.002. Epub 2019 Sep 10. No abstract available.

PMID:
31606066
18.

NGF protects neuroblastoma cells against β-amyloid-induced apoptosis via the /HO-1 pathway.

Su R, Su W, Jiao Q.

FEBS Open Bio. 2019 Oct 12. doi: 10.1002/2211-5463.12742. [Epub ahead of print]

19.

The PERK/Nrf2 pathway mediates endoplasmic reticulum stress-induced injury by upregulating endoplasmic reticulophagy in H9c2 cardiomyoblasts.

Tao T, Wang J, Wang X, Wang Y, Mao H, Liu X.

Life Sci. 2019 Oct 8:116944. doi: 10.1016/j.lfs.2019.116944. [Epub ahead of print]

PMID:
31604108
20.

Salvianolic acid B exerts a protective effect in acute liver injury by regulating the Nrf2/HO-1 signaling pathway.

Jin Y, Tao X, Shi Y, Lu Y, Mei J.

Can J Physiol Pharmacol. 2019 Oct 11. doi: 10.1139/cjpp-2019-0349. [Epub ahead of print]

PMID:
31604020

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