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Items: 1 to 20 of 65

1.

Rapid MALDI mass spectrometry imaging for surgical pathology.

Basu SS, Regan MS, Randall EC, Abdelmoula WM, Clark AR, Gimenez-Cassina Lopez B, Cornett DS, Haase A, Santagata S, Agar NYR.

NPJ Precis Oncol. 2019 Jul 4;3:17. doi: 10.1038/s41698-019-0089-y. eCollection 2019.

2.

Quantitative Wide-Field Imaging Techniques for Fluorescence Guided Neurosurgery.

Valdes PA, Juvekar P, Agar NYR, Gioux S, Golby AJ.

Front Surg. 2019 Jun 6;6:31. doi: 10.3389/fsurg.2019.00031. eCollection 2019. Review.

3.

A large-scale drug screen identifies selective inhibitors of class I HDACs as a potential therapeutic option for SHH medulloblastoma.

Pak E, MacKenzie EL, Zhao X, Pazyra-Murphy MF, Park PMC, Wu L, Shaw DL, Addleson EC, Cayer SS, Lopez BG, Agar NYR, Rubin LL, Qi J, Merk DJ, Segal RA.

Neuro Oncol. 2019 May 16. pii: noz089. doi: 10.1093/neuonc/noz089. [Epub ahead of print]

PMID:
31111916
4.

Metal Oxide Laser Ionization Mass Spectrometry Imaging (MOLI MSI) Using Cerium(IV) Oxide.

Basu SS, McMinn MH, Giménez-Cassina Lopéz B, Regan MS, Randall EC, Clark AR, Cox CR, Agar NYR.

Anal Chem. 2019 May 21;91(10):6800-6807. doi: 10.1021/acs.analchem.9b00894. Epub 2019 May 8.

PMID:
31025851
5.

Automatic 3D Nonlinear Registration of Mass Spectrometry Imaging and Magnetic Resonance Imaging Data.

Abdelmoula WM, Regan MS, Lopez BGC, Randall EC, Lawler S, Mladek AC, Nowicki MO, Marin BM, Agar JN, Swanson KR, Kapur T, Sarkaria JN, Wells W, Agar NYR.

Anal Chem. 2019 May 7;91(9):6206-6216. doi: 10.1021/acs.analchem.9b00854. Epub 2019 Apr 22.

PMID:
30932478
6.

Genetically Encoded Fluorescent Proteins Enable High-Throughput Assignment of Cell Cohorts Directly from MALDI-MS Images.

Schmitt ND, Rawlins CM, Randall EC, Wang X, Koller A, Auclair JR, Kowalski JM, Kowalski PJ, Luther E, Ivanov AR, Agar NYR, Agar JN.

Anal Chem. 2019 Mar 19;91(6):3810-3817. doi: 10.1021/acs.analchem.8b03454. Epub 2019 Mar 6.

PMID:
30839199
7.

Molecular Characterization of Prostate Cancer with Associated Gleason Score Using Mass Spectrometry Imaging.

Randall EC, Zadra G, Chetta P, Lopez BGC, Syamala S, Basu SS, Agar JN, Loda M, Tempany CM, Fennessy FM, Agar NYR.

Mol Cancer Res. 2019 May;17(5):1155-1165. doi: 10.1158/1541-7786.MCR-18-1057. Epub 2019 Feb 11.

PMID:
30745465
8.

Buparlisib in Patients With Recurrent Glioblastoma Harboring Phosphatidylinositol 3-Kinase Pathway Activation: An Open-Label, Multicenter, Multi-Arm, Phase II Trial.

Wen PY, Touat M, Alexander BM, Mellinghoff IK, Ramkissoon S, McCluskey CS, Pelton K, Haidar S, Basu SS, Gaffey SC, Brown LE, Martinez-Ledesma JE, Wu S, Kim J, Wei W, Park MA, Huse JT, Kuhn JG, Rinne ML, Colman H, Agar NYR, Omuro AM, DeAngelis LM, Gilbert MR, de Groot JF, Cloughesy TF, Chi AS, Roberts TM, Zhao JJ, Lee EQ, Nayak L, Heath JR, Horky LL, Batchelor TT, Beroukhim R, Chang SM, Ligon AH, Dunn IF, Koul D, Young GS, Prados MD, Reardon DA, Yung WKA, Ligon KL.

J Clin Oncol. 2019 Mar 20;37(9):741-750. doi: 10.1200/JCO.18.01207. Epub 2019 Feb 4.

9.

Integrated mapping of pharmacokinetics and pharmacodynamics in a patient-derived xenograft model of glioblastoma.

Randall EC, Emdal KB, Laramy JK, Kim M, Roos A, Calligaris D, Regan MS, Gupta SK, Mladek AC, Carlson BL, Johnson AJ, Lu FK, Xie XS, Joughin BA, Reddy RJ, Peng S, Abdelmoula WM, Jackson PR, Kolluri A, Kellersberger KA, Agar JN, Lauffenburger DA, Swanson KR, Tran NL, Elmquist WF, White FM, Sarkaria JN, Agar NYR.

Nat Commun. 2018 Nov 21;9(1):4904. doi: 10.1038/s41467-018-07334-3.

10.

Blood-brain-barrier organoids for investigating the permeability of CNS therapeutics.

Bergmann S, Lawler SE, Qu Y, Fadzen CM, Wolfe JM, Regan MS, Pentelute BL, Agar NYR, Cho CF.

Nat Protoc. 2018 Dec;13(12):2827-2843. doi: 10.1038/s41596-018-0066-x.

PMID:
30382243
11.

Rapid discrimination of pediatric brain tumors by mass spectrometry imaging.

Clark AR, Calligaris D, Regan MS, Pomeranz Krummel D, Agar JN, Kallay L, MacDonald T, Schniederjan M, Santagata S, Pomeroy SL, Agar NYR, Sengupta S.

J Neurooncol. 2018 Nov;140(2):269-279. doi: 10.1007/s11060-018-2978-2. Epub 2018 Aug 20.

12.

Efficacy of the MDM2 Inhibitor SAR405838 in Glioblastoma Is Limited by Poor Distribution Across the Blood-Brain Barrier.

Kim M, Ma DJ, Calligaris D, Zhang S, Feathers RW, Vaubel RA, Meaux I, Mladek AC, Parrish KE, Jin F, Barriere C, Debussche L, Watters J, Tian S, Decker PA, Eckel-Passow JE, Kitange GJ, Johnson AJ, Parney IF, Anastasiadis PZ, Agar NYR, Elmquist WF, Sarkaria JN.

Mol Cancer Ther. 2018 Sep;17(9):1893-1901. doi: 10.1158/1535-7163.MCT-17-0600. Epub 2018 Jul 3.

PMID:
29970480
13.

In Vitro Liquid Extraction Surface Analysis Mass Spectrometry (ivLESA-MS) for Direct Metabolic Analysis of Adherent Cells in Culture.

Basu SS, Randall EC, Regan MS, Lopez BGC, Clark AR, Schmitt ND, Agar JN, Dillon DA, Agar NYR.

Anal Chem. 2018 Apr 17;90(8):4987-4991. doi: 10.1021/acs.analchem.8b00530. Epub 2018 Apr 2.

14.

Unique Intradural Inflammatory Mass Containing Precipitated Morphine: Confirmatory Analysis by LESA-MS and MALDI-MS.

Kim AJ, Basu S, Glass C, Ross EL, Agar N, He Q, Calligaris D.

Pain Pract. 2018 Sep;18(7):889-894. doi: 10.1111/papr.12688. Epub 2018 Mar 30.

PMID:
29480977
15.

Prostate cancer diagnosis and characterization with mass spectrometry imaging.

Kurreck A, Vandergrift LA, Fuss TL, Habbel P, Agar NYR, Cheng LL.

Prostate Cancer Prostatic Dis. 2018 Sep;21(3):297-305. doi: 10.1038/s41391-017-0011-z. Epub 2017 Dec 5. Review.

16.

Is the blood-brain barrier really disrupted in all glioblastomas? A critical assessment of existing clinical data.

Sarkaria JN, Hu LS, Parney IF, Pafundi DH, Brinkmann DH, Laack NN, Giannini C, Burns TC, Kizilbash SH, Laramy JK, Swanson KR, Kaufmann TJ, Brown PD, Agar NYR, Galanis E, Buckner JC, Elmquist WF.

Neuro Oncol. 2018 Jan 22;20(2):184-191. doi: 10.1093/neuonc/nox175. Review.

17.

Coordinated Splicing of Regulatory Detained Introns within Oncogenic Transcripts Creates an Exploitable Vulnerability in Malignant Glioma.

Braun CJ, Stanciu M, Boutz PL, Patterson JC, Calligaris D, Higuchi F, Neupane R, Fenoglio S, Cahill DP, Wakimoto H, Agar NYR, Yaffe MB, Sharp PA, Hemann MT, Lees JA.

Cancer Cell. 2017 Oct 9;32(4):411-426.e11. doi: 10.1016/j.ccell.2017.08.018. Epub 2017 Sep 28.

18.

Osteoglycin promotes meningioma development through downregulation of NF2 and activation of mTOR signaling.

Mei Y, Du Z, Hu C, Greenwald NF, Abedalthagafi M, Agar NYR, Dunn GP, Bi WL, Santagata S, Dunn IF.

Cell Commun Signal. 2017 Sep 18;15(1):34. doi: 10.1186/s12964-017-0189-7.

19.

Blood-brain-barrier spheroids as an in vitro screening platform for brain-penetrating agents.

Cho CF, Wolfe JM, Fadzen CM, Calligaris D, Hornburg K, Chiocca EA, Agar NYR, Pentelute BL, Lawler SE.

Nat Commun. 2017 Jun 6;8:15623. doi: 10.1038/ncomms15623.

20.

Genomic profile of human meningioma cell lines.

Mei Y, Bi WL, Greenwald NF, Agar NY, Beroukhim R, Dunn GP, Dunn IF.

PLoS One. 2017 May 26;12(5):e0178322. doi: 10.1371/journal.pone.0178322. eCollection 2017.

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