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Items: 1 to 20 of 69

1.

LLGL2 rescues nutrient stress by promoting leucine uptake in ER+ breast cancer.

Saito Y, Li L, Coyaud E, Luna A, Sander C, Raught B, Asara JM, Brown M, Muthuswamy SK.

Nature. 2019 May;569(7755):275-279. doi: 10.1038/s41586-019-1126-2. Epub 2019 Apr 17.

PMID:
30996345
2.

Golgi Stabilization, Not Its Front-Rear Bias, Is Associated with EMT-Enhanced Fibrillar Migration.

Natividad RJ, Lalli ML, Muthuswamy SK, Asthagiri AR.

Biophys J. 2018 Nov 20;115(10):2067-2077. doi: 10.1016/j.bpj.2018.10.006. Epub 2018 Oct 11.

PMID:
30366626
3.

Reporters to mark and eliminate basal or luminal epithelial cells in culture and in vivo.

Sonzogni O, Haynes J, Seifried LA, Kamel YM, Huang K, BeGora MD, Yeung FA, Robert-Tissot C, Heng YJ, Yuan X, Wulf GM, Kron KJ, Wagenblast E, Lupien M, Kislinger T, Hannon GJ, Muthuswamy SK.

PLoS Biol. 2018 Jun 20;16(6):e2004049. doi: 10.1371/journal.pbio.2004049. eCollection 2018 Jun.

4.

Organoid Models of Cancer Explode with Possibilities.

Muthuswamy SK.

Cell Stem Cell. 2018 Mar 1;22(3):290-291. doi: 10.1016/j.stem.2018.02.010.

5.

Editorial overview: Cell differentiation and development: New kids in the block-new tools and concepts opening new doors in development.

Götz M, Muthuswamy SK.

Curr Opin Cell Biol. 2017 Dec;49:iv-v. doi: 10.1016/j.ceb.2018.01.012. No abstract available.

PMID:
29463399
6.

Reinterpreting polarity and cancer: The changing landscape from tumor suppression to tumor promotion.

Saito Y, Desai RR, Muthuswamy SK.

Biochim Biophys Acta Rev Cancer. 2018 Apr;1869(2):103-116. doi: 10.1016/j.bbcan.2017.12.001. Epub 2018 Jan 31. Review.

PMID:
29369778
7.

Personalized RNA Medicine for Pancreatic Cancer.

Gilles ME, Hao L, Huang L, Rupaimoole R, Lopez-Casas PP, Pulver E, Jeong JC, Muthuswamy SK, Hidalgo M, Bhatia SN, Slack FJ.

Clin Cancer Res. 2018 Apr 1;24(7):1734-1747. doi: 10.1158/1078-0432.CCR-17-2733. Epub 2018 Jan 12.

8.

Prostate cancer-associated SPOP mutations confer resistance to BET inhibitors through stabilization of BRD4.

Dai X, Gan W, Li X, Wang S, Zhang W, Huang L, Liu S, Zhong Q, Guo J, Zhang J, Chen T, Shimizu K, Beca F, Blattner M, Vasudevan D, Buckley DL, Qi J, Buser L, Liu P, Inuzuka H, Beck AH, Wang L, Wild PJ, Garraway LA, Rubin MA, Barbieri CE, Wong KK, Muthuswamy SK, Huang J, Chen Y, Bradner JE, Wei W.

Nat Med. 2017 Sep;23(9):1063-1071. doi: 10.1038/nm.4378. Epub 2017 Aug 14.

9.

Bringing together the organoid field: from early beginnings to the road ahead.

Muthuswamy SK.

Development. 2017 Mar 15;144(6):963-967. doi: 10.1242/dev.144444. Review.

10.

An interaction between Scribble and the NADPH oxidase complex controls M1 macrophage polarization and function.

Zheng W, Umitsu M, Jagan I, Tran CW, Ishiyama N, BeGora M, Araki K, Ohashi PS, Ikura M, Muthuswamy SK.

Nat Cell Biol. 2016 Nov;18(11):1244-1252. doi: 10.1038/ncb3413. Epub 2016 Oct 3.

PMID:
27694890
11.

Positive Quantitative Relationship between EMT and Contact-Initiated Sliding on Fiber-like Tracks.

Milano DF, Natividad RJ, Saito Y, Luo CY, Muthuswamy SK, Asthagiri AR.

Biophys J. 2016 Oct 4;111(7):1569-1574. doi: 10.1016/j.bpj.2016.08.037.

12.

Scribble is required for pregnancy-induced alveologenesis in the adult mammary gland.

Baker L, BeGora M, Au Yeung F, Feigin ME, Rosenberg AZ, Lowe SW, Kislinger T, Muthuswamy SK.

J Cell Sci. 2016 Jun 15;129(12):2307-15. doi: 10.1242/jcs.185413. Epub 2016 May 13.

13.

Regulators of Metastasis Modulate the Migratory Response to Cell Contact under Spatial Confinement.

Milano DF, Ngai NA, Muthuswamy SK, Asthagiri AR.

Biophys J. 2016 Apr 26;110(8):1886-1895. doi: 10.1016/j.bpj.2016.02.040.

14.

Ductal pancreatic cancer modeling and drug screening using human pluripotent stem cell- and patient-derived tumor organoids.

Huang L, Holtzinger A, Jagan I, BeGora M, Lohse I, Ngai N, Nostro C, Wang R, Muthuswamy LB, Crawford HC, Arrowsmith C, Kalloger SE, Renouf DJ, Connor AA, Cleary S, Schaeffer DF, Roehrl M, Tsao MS, Gallinger S, Keller G, Muthuswamy SK.

Nat Med. 2015 Nov;21(11):1364-71. doi: 10.1038/nm.3973. Epub 2015 Oct 26.

15.

A novel phosphatidic acid-protein-tyrosine phosphatase D2 axis is essential for ERBB2 signaling in mammary epithelial cells.

Ramesh M, Krishnan N, Muthuswamy SK, Tonks NK.

J Biol Chem. 2015 Apr 10;290(15):9646-59. doi: 10.1074/jbc.M114.627968. Epub 2015 Feb 13.

16.

Targeting the disordered C terminus of PTP1B with an allosteric inhibitor.

Krishnan N, Koveal D, Miller DH, Xue B, Akshinthala SD, Kragelj J, Jensen MR, Gauss CM, Page R, Blackledge M, Muthuswamy SK, Peti W, Tonks NK.

Nat Chem Biol. 2014 Jul;10(7):558-66. doi: 10.1038/nchembio.1528. Epub 2014 May 20.

17.

Mislocalization of the cell polarity protein scribble promotes mammary tumorigenesis and is associated with basal breast cancer.

Feigin ME, Akshinthala SD, Araki K, Rosenberg AZ, Muthuswamy LB, Martin B, Lehmann BD, Berman HK, Pietenpol JA, Cardiff RD, Muthuswamy SK.

Cancer Res. 2014 Jun 1;74(11):3180-94. doi: 10.1158/0008-5472.CAN-13-3415. Epub 2014 Mar 24.

18.

G-protein-coupled receptor GPR161 is overexpressed in breast cancer and is a promoter of cell proliferation and invasion.

Feigin ME, Xue B, Hammell MC, Muthuswamy SK.

Proc Natl Acad Sci U S A. 2014 Mar 18;111(11):4191-6. doi: 10.1073/pnas.1320239111. Epub 2014 Mar 5.

19.

Loss of Par3 promotes breast cancer metastasis by compromising cell-cell cohesion.

Xue B, Krishnamurthy K, Allred DC, Muthuswamy SK.

Nat Cell Biol. 2013 Feb;15(2):189-200. doi: 10.1038/ncb2663. Epub 2012 Dec 23.

20.

Rotational motion during three-dimensional morphogenesis of mammary epithelial acini relates to laminin matrix assembly.

Wang H, Lacoche S, Huang L, Xue B, Muthuswamy SK.

Proc Natl Acad Sci U S A. 2013 Jan 2;110(1):163-8. doi: 10.1073/pnas.1201141110. Epub 2012 Dec 17.

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