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90 results

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Page 1
Clinical pitfalls and serological diagnostics of MuSK myasthenia gravis.
Kwon YN, Woodhall M, Sung JJ, Kim KK, Lim YM, Kim H, Kim JE, Baek SH, Kim BJ, Park JS, Seok HY, Kim DS, Kwon O, Park KH, Sohn E, Bae JS, Yoon BN, Kim NH, Ahn SW, Choi K, Oh J, Park HJ, Shin KJ, Lee S, Park J, Kim SH, Seok JI, Bae DW, An JY, Joo IS, Choi SJ, Nam TS, Kim S, Park KJ, Kwon KH, Waters P, Hong YH. Kwon YN, et al. J Neurol. 2023 Mar;270(3):1478-1486. doi: 10.1007/s00415-022-11458-4. Epub 2022 Nov 17. J Neurol. 2023. PMID: 36396811 Free PMC article.
Clinical data were compared between anti-MuSK Ab-positive MG and double seronegative (AChR and MuSK) MG groups. RESULTS: After excluding non-MG and clustered AChR Ab-positive patients, we identified 89 patients as a cohort of AChR Ab-negative generalized MG. …
Clinical data were compared between anti-MuSK Ab-positive MG and double seronegative (AChR and MuSK) MG groups. RESULTS: After …
Repetitive Nerve Stimulation in MuSK-Antibody-Positive Myasthenia Gravis.
Kim SW, Sunwoo MK, Kim SM, Shin HY, Sunwoo IN. Kim SW, et al. J Clin Neurol. 2017 Jul;13(3):287-292. doi: 10.3988/jcn.2017.13.3.287. Epub 2017 May 15. J Clin Neurol. 2017. PMID: 28516744 Free PMC article.
We analyzed the RNS responses of limb and facial muscles in MuSK-Ab-positive and acetylcholine receptor (AChR)-Ab-negative MG (MuSK MG) and MuSK-Ab-negative and AChR-Ab-negative [double-seronegative (DSN)] MG patients. ...CONCLUSIONS: Abnormal RNS responses p …
We analyzed the RNS responses of limb and facial muscles in MuSK-Ab-positive and acetylcholine receptor (AChR)-Ab-negative MG (MuS …
Effects of Musk Volatile Compounds on Attenuated Nerve Injury and Improving Post-cerebral Ischemic Exercise Functions.
Wang D, Zhang MM, Wu CJ, Liang Q, Wei DN, He L, Ye X. Wang D, et al. Curr Pharm Des. 2022;28(23):1932-1948. doi: 10.2174/1381612828666220526154014. Curr Pharm Des. 2022. PMID: 35619259
OBJECTIVE: This study was aimed to test the hypotheses that volatile compounds of musk could attenuate nerve injury and identify the bioactive compounds and potential mechanisms of Musk. ...Next, twenty potential flavor active compounds were recognized by GC-O-MS. A …
OBJECTIVE: This study was aimed to test the hypotheses that volatile compounds of musk could attenuate nerve injury and identify the …
Electrophysiological profile of the patients with MuSK positive myasthenia gravis.
Nikolic A, Basta I, Stojanovic VR, Stevic Z, Lavrnic D. Nikolic A, et al. Neurol Res. 2014 Nov;36(11):945-9. doi: 10.1179/1743132814Y.0000000387. Epub 2014 May 14. Neurol Res. 2014. PMID: 24825477

RESULTS: Pathological RNS was verified in 16 (51.6%) MuSK and 26 (92.9%) AChR MG patients (P < 0.01). Pathological jitter analysis was registered in 28 (90.3%) MuSK and 26 (92.9%) AChR MG patients (P > 0.05). Increased jitter was present in extensor digitorum

…

RESULTS: Pathological RNS was verified in 16 (51.6%) MuSK and 26 (92.9%) AChR MG patients (P < 0.01). Pathological jitter analysis

…
A brighter shade of future climate on Himalayan musk deer Moschus leucogaster.
Mainali KP, Singh PB, Evans M, Adhikari A, Hu Y, Hu H. Mainali KP, et al. Sci Rep. 2023 Aug 7;13(1):12771. doi: 10.1038/s41598-023-39481-z. Sci Rep. 2023. PMID: 37550330 Free PMC article.
Himalayan musk deer (Moschus leucogaster) is classified as an endangered species by IUCN with a historically misunderstood distribution due to misidentification with other species of musk deer, Moschus spp. ...The most influential determinants of the distribution of …
Himalayan musk deer (Moschus leucogaster) is classified as an endangered species by IUCN with a historically misunderstood distributi …
Regulatory Roles of Peroxisomal Metabolic Pathways Involved in Musk Secretion in Muskrats.
Zhang M, Yang S, Shi M, Zhang S, Zhang T, Li Y, Xu S, Cha M, Meng Y, Lin S, Yu J, Li X, Mu A, Hu D, Liu S. Zhang M, et al. J Membr Biol. 2019 Feb;252(1):61-75. doi: 10.1007/s00232-018-0057-4. Epub 2019 Jan 2. J Membr Biol. 2019. PMID: 30604068
In this study, we analyzed the main components of muskrat musk by gas chromatography-mass spectrometry, the results showed that muskrat musk contained fatty acids (29.32%), esters (31.89%), cholesterol (4.38%), cyclic ketones (16.31%), alcohols (6.42%) and ot …
In this study, we analyzed the main components of muskrat musk by gas chromatography-mass spectrometry, the results showed that muskr …
Neurophysiological and mitochondrial abnormalities in MuSK antibody seropositive myasthenia gravis compared to other immunological subtypes.
Rostedt Punga A, Ahlqvist K, Bartoccioni E, Scuderi F, Marino M, Suomalainen A, Kalimo H, Stålberg EV. Rostedt Punga A, et al. Clin Neurophysiol. 2006 Jul;117(7):1434-43. doi: 10.1016/j.clinph.2006.03.028. Epub 2006 Jun 5. Clin Neurophysiol. 2006. PMID: 16737845
SFEMG was abnormal in all examined MuSK(+) patients. All 7 biopsied MuSK(+) and 32 MuSK(-) patients (89%) had cytochrome c oxidase (COX) negative fibers. Three of five MuSK(+) and 13 of 20 MuSK(-) patients analyzed had multiple mtDNA dele …
SFEMG was abnormal in all examined MuSK(+) patients. All 7 biopsied MuSK(+) and 32 MuSK(-) patients (89%) had cy …
Clinical features, treatment and prognosis of MuSK antibody-associated myasthenia gravis in Northwest China: a single-centre retrospective cohort study.
Zhao S, Zhang K, Ren K, Lu J, Ma C, Zhao C, Li Z, Guo J. Zhao S, et al. BMC Neurol. 2021 Nov 4;21(1):428. doi: 10.1186/s12883-021-02439-7. BMC Neurol. 2021. PMID: 34732168 Free PMC article.
METHODS: Eighteen MuSK-MG patients admitted in our department between October 2017 and September 2020 were included. Clinical parameters were collected and the responses to different immunosuppressive drugs were assessed by MGFA Postintervention Status (MGFA-PIS). Meanwhil …
METHODS: Eighteen MuSK-MG patients admitted in our department between October 2017 and September 2020 were included. Clinical paramet …
The biological significance of ω-oxidation of fatty acids.
Miura Y. Miura Y. Proc Jpn Acad Ser B Phys Biol Sci. 2013;89(8):370-82. doi: 10.2183/pjab.89.370. Proc Jpn Acad Ser B Phys Biol Sci. 2013. PMID: 24126285 Free PMC article. Review.
It is observed that omega- and (omega-1)-oxidation of fatty acids are related to energy metabolism in some laboratory animals such as musk shrews and Mongolian gerbils. Studies confirmed that omega- and (omega-1)-oxidation of fatty acids play crucial roles in the productio …
It is observed that omega- and (omega-1)-oxidation of fatty acids are related to energy metabolism in some laboratory animals such as mus …
Therapeutic Responses to Efgartigimod for Generalized Myasthenia Gravis in Japan.
Suzuki S, Uzawa A, Nagane Y, Masuda M, Konno S, Kubota T, Samukawa M, Ishizuchi K, Tokuyasu D, Handa H, Yasuda M, Kawaguchi N, Kimura T, Suzuki Y, Sugimoto T, Minami N, Takahashi MP, Murai H, Utsugisawa K. Suzuki S, et al. Neurol Clin Pract. 2024 Jun;14(3):e200276. doi: 10.1212/CPJ.0000000000200276. Epub 2024 Mar 25. Neurol Clin Pract. 2024. PMID: 38544885 Free PMC article.
Their serologic profiles were as follows: AChR+, n = 19 (53%); MuSK+, n = 6 (17%); and seronegative, n = 11 (31%). Twenty-six patients (72%) had refractory MG. ...The duration of effectiveness of efgartigimod was varied among the responders; 4 responders had only a single …
Their serologic profiles were as follows: AChR+, n = 19 (53%); MuSK+, n = 6 (17%); and seronegative, n = 11 (31%). Twenty-six patient …
90 results