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Items: 5

1.

Identification of dual Sigma1 receptor modulators/acetylcholinesterase inhibitors with antioxidant and neurotrophic properties, as neuroprotective agents.

Rui M, Rossino G, Coniglio S, Monteleone S, Scuteri A, Malacrida A, Rossi D, Catenacci L, Sorrenti M, Paolillo M, Curti D, Venturini L, Schepmann D, Wünsch B, Liedl KR, Cavaletti G, Pace V, Urban E, Collina S.

Eur J Med Chem. 2018 Oct 5;158:353-370. doi: 10.1016/j.ejmech.2018.09.010. Epub 2018 Sep 8.

PMID:
30223122
2.

Mechanisms Responsible for ω-Pore Currents in Cav Calcium Channel Voltage-Sensing Domains.

Monteleone S, Lieb A, Pinggera A, Negro G, Fuchs JE, Hofer F, Striessnig J, Tuluc P, Liedl KR.

Biophys J. 2017 Oct 3;113(7):1485-1495. doi: 10.1016/j.bpj.2017.08.010.

3.

Molecular Connectivity Predefines Polypharmacology: Aliphatic Rings, Chirality, and sp3 Centers Enhance Target Selectivity.

Monteleone S, Fuchs JE, Liedl KR.

Front Pharmacol. 2017 Aug 28;8:552. doi: 10.3389/fphar.2017.00552. eCollection 2017.

4.

Gaining in pan-affinity towards sigma 1 and sigma 2 receptors. SAR studies on arylalkylamines.

Rossi D, Rui M, Di Giacomo M, Schepmann D, Wünsch B, Monteleone S, Liedl KR, Collina S.

Bioorg Med Chem. 2017 Jan 1;25(1):11-19. doi: 10.1016/j.bmc.2016.10.005. Epub 2016 Oct 11.

PMID:
27838169
5.

CACNA1D de novo mutations in autism spectrum disorders activate Cav1.3 L-type calcium channels.

Pinggera A, Lieb A, Benedetti B, Lampert M, Monteleone S, Liedl KR, Tuluc P, Striessnig J.

Biol Psychiatry. 2015 May 1;77(9):816-22. doi: 10.1016/j.biopsych.2014.11.020. Epub 2014 Dec 8.

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