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Items: 1 to 20 of 28

1.

Gain-of-Function Mutations in the Phospholipid Flippase MprF Confer Specific Daptomycin Resistance.

Ernst CM, Slavetinsky CJ, Kuhn S, Hauser JN, Nega M, Mishra NN, Gekeler C, Bayer AS, Peschel A.

MBio. 2018 Dec 18;9(6). pii: e01659-18. doi: 10.1128/mBio.01659-18.

2.

Impact of Multiple Single-Nucleotide Polymorphisms Within mprF on Daptomycin Resistance in Staphylococcus aureus.

Yang SJ, Mishra NN, Kang KM, Lee GY, Park JH, Bayer AS.

Microb Drug Resist. 2018 Oct;24(8):1075-1081. doi: 10.1089/mdr.2017.0156. Epub 2018 Jan 30.

PMID:
29381428
3.

Phenotypic and genotypic correlates of daptomycin-resistant methicillin-susceptible Staphylococcus aureus clinical isolates.

Kang KM, Mishra NN, Park KT, Lee GY, Park YH, Bayer AS, Yang SJ.

J Microbiol. 2017 Feb;55(2):153-159. doi: 10.1007/s12275-017-6509-1. Epub 2017 Jan 26.

4.

Dysregulation of mprF and dltABCD expression among daptomycin-non-susceptible MRSA clinical isolates.

Bayer AS, Mishra NN, Cheung AL, Rubio A, Yang SJ.

J Antimicrob Chemother. 2016 Aug;71(8):2100-4. doi: 10.1093/jac/dkw142. Epub 2016 Apr 27.

5.

The role of Staphylococcal carotenogenesis in resistance to host defense peptides and in vivo virulence in experimental endocarditis model.

Xiong YQ, Yang SJ, Tong SY, Alvarez DN, Mishra NN.

Pathog Dis. 2015 Oct;73(7). pii: ftv056. doi: 10.1093/femspd/ftv056. Epub 2015 Aug 4.

6.
7.

Heterogeneity of mprF sequences in methicillin-resistant Staphylococcus aureus clinical isolates: role in cross-resistance between daptomycin and host defense antimicrobial peptides.

Bayer AS, Mishra NN, Sakoulas G, Nonejuie P, Nast CC, Pogliano J, Chen KT, Ellison SN, Yeaman MR, Yang SJ.

Antimicrob Agents Chemother. 2014 Dec;58(12):7462-7. doi: 10.1128/AAC.03422-14. Epub 2014 Oct 6.

8.

Phenotypic and genotypic characterization of daptomycin-resistant methicillin-resistant Staphylococcus aureus strains: relative roles of mprF and dlt operons.

Mishra NN, Bayer AS, Weidenmaier C, Grau T, Wanner S, Stefani S, Cafiso V, Bertuccio T, Yeaman MR, Nast CC, Yang SJ.

PLoS One. 2014 Sep 16;9(9):e107426. doi: 10.1371/journal.pone.0107426. eCollection 2014.

9.

Synthesis of 2,3,6-trideoxy sugar triazole hybrids as potential new broad spectrum antimicrobial agents.

Sharma S, Saquib M, Verma S, Mishra NN, Shukla PK, Srivastava R, Prabhakar YS, Shaw AK.

Eur J Med Chem. 2014 Aug 18;83:474-89. doi: 10.1016/j.ejmech.2014.06.048. Epub 2014 Jun 24.

PMID:
24992075
10.

Causal role of single nucleotide polymorphisms within the mprF gene of Staphylococcus aureus in daptomycin resistance.

Yang SJ, Mishra NN, Rubio A, Bayer AS.

Antimicrob Agents Chemother. 2013 Nov;57(11):5658-64. doi: 10.1128/AAC.01184-13. Epub 2013 Sep 3.

11.

Emergence of daptomycin resistance in daptomycin-naïve rabbits with methicillin-resistant Staphylococcus aureus prosthetic joint infection is associated with resistance to host defense cationic peptides and mprF polymorphisms.

Mishra NN, Yang SJ, Chen L, Muller C, Saleh-Mghir A, Kuhn S, Peschel A, Yeaman MR, Nast CC, Kreiswirth BN, Crémieux AC, Bayer AS.

PLoS One. 2013 Aug 19;8(8):e71151. doi: 10.1371/journal.pone.0071151. eCollection 2013.

12.

Increased cell wall teichoic acid production and D-alanylation are common phenotypes among daptomycin-resistant methicillin-resistant Staphylococcus aureus (MRSA) clinical isolates.

Bertsche U, Yang SJ, Kuehner D, Wanner S, Mishra NN, Roth T, Nega M, Schneider A, Mayer C, Grau T, Bayer AS, Weidenmaier C.

PLoS One. 2013 Jun 13;8(6):e67398. doi: 10.1371/journal.pone.0067398. Print 2013.

13.

Virulence of endemic nonpigmented northern Australian Staphylococcus aureus clone (clonal complex 75, S. argenteus) is not augmented by staphyloxanthin.

Tong SY, Sharma-Kuinkel BK, Thaden JT, Whitney AR, Yang SJ, Mishra NN, Rude T, Lilliebridge RA, Selim MA, Ahn SH, Holt DC, Giffard PM, Bayer AS, Deleo FR, Fowler VG Jr.

J Infect Dis. 2013 Aug 1;208(3):520-7. doi: 10.1093/infdis/jit173. Epub 2013 Apr 18.

14.

Correlation of cell membrane lipid profiles with daptomycin resistance in methicillin-resistant Staphylococcus aureus.

Mishra NN, Bayer AS.

Antimicrob Agents Chemother. 2013 Feb;57(2):1082-5. doi: 10.1128/AAC.02182-12. Epub 2012 Dec 17.

17.
18.

The Staphylococcus aureus two-component regulatory system, GraRS, senses and confers resistance to selected cationic antimicrobial peptides.

Yang SJ, Bayer AS, Mishra NN, Meehl M, Ledala N, Yeaman MR, Xiong YQ, Cheung AL.

Infect Immun. 2012 Jan;80(1):74-81. doi: 10.1128/IAI.05669-11. Epub 2011 Oct 10.

19.

In vitro cross-resistance to daptomycin and host defense cationic antimicrobial peptides in clinical methicillin-resistant Staphylococcus aureus isolates.

Mishra NN, McKinnell J, Yeaman MR, Rubio A, Nast CC, Chen L, Kreiswirth BN, Bayer AS.

Antimicrob Agents Chemother. 2011 Sep;55(9):4012-8. doi: 10.1128/AAC.00223-11. Epub 2011 Jun 27.

20.

Synthesis and antibacterial evaluation of novel 8-fluoro Norfloxacin derivatives as potential probes for methicillin and vancomycin-resistant Staphylococcus aureus.

Sunduru N, Gupta L, Chauhan K, Mishra NN, Shukla PK, Chauhan PM.

Eur J Med Chem. 2011 Apr;46(4):1232-44. doi: 10.1016/j.ejmech.2011.01.044. Epub 2011 Feb 3.

PMID:
21345548

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