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2005 2
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593 results

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MicroRNA schizophrenia: Etiology, biomarkers and therapeutic targets.
Zhang HC, Du Y, Chen L, Yuan ZQ, Cheng Y. Zhang HC, et al. Neurosci Biobehav Rev. 2023 Mar;146:105064. doi: 10.1016/j.neubiorev.2023.105064. Epub 2023 Jan 24. Neurosci Biobehav Rev. 2023. PMID: 36707012 Review.
The three sets of symptoms associated with schizophrenia-positive, negative, and cognitive-are burdensome and have serious effects on public health, which affects up to 1% of the population. ...Small noncoding RNA molecules called microRNAs (miRNAs) have come to lig …
The three sets of symptoms associated with schizophrenia-positive, negative, and cognitive-are burdensome and have serious effects on …
Epigenetics of Schizophrenia.
Srivastava A, Dada O, Qian J, Al-Chalabi N, Fatemi AB, Gerretsen P, Graff A, De Luca V. Srivastava A, et al. Psychiatry Res. 2021 Nov;305:114218. doi: 10.1016/j.psychres.2021.114218. Epub 2021 Sep 22. Psychiatry Res. 2021. PMID: 34638051 Review.
Schizophrenia (SCZ) is a chronic psychotic disorder that contributes significantly to disability, affecting behavior, thought, and cognition. It has long been known that there is a heritable component to schizophrenia; studies in both the pre-genomic and post-genomi
Schizophrenia (SCZ) is a chronic psychotic disorder that contributes significantly to disability, affecting behavior, thought, and co
MicroRNA dysregulation in schizophrenia.
Beveridge NJ, Cairns MJ. Beveridge NJ, et al. Neurobiol Dis. 2012 May;46(2):263-71. doi: 10.1016/j.nbd.2011.12.029. Epub 2011 Dec 21. Neurobiol Dis. 2012. PMID: 22207190 Free article. Review.
Schizophrenia is a complex neuropsychiatric disorder that involves disturbances in neural circuitry and synaptic function. ...They are emerging as key regulators of many neurodevelopmental and neurological processes as their dysregulation could lead to pervasive changes in
Schizophrenia is a complex neuropsychiatric disorder that involves disturbances in neural circuitry and synaptic function. ...They ar
Identification of Ferroptosis-Related Genes in Schizophrenia Based on Bioinformatic Analysis.
Feng S, Chen J, Qu C, Yang L, Wu X, Wang S, Yang T, Liu H, Fang Y, Sun P. Feng S, et al. Genes (Basel). 2022 Nov 20;13(11):2168. doi: 10.3390/genes13112168. Genes (Basel). 2022. PMID: 36421842 Free PMC article.
The purpose of this study is to explore the correlation between ferroptosis-related genes and schizophrenia in order to explore the new direction of diagnosis and treatment of schizophrenia. ...Hub genes associated with ferroptosis were validated using other schi
The purpose of this study is to explore the correlation between ferroptosis-related genes and schizophrenia in order to explore the n …
Epigenomic Dysregulation in Schizophrenia: In Search of Disease Etiology and Biomarkers.
Khavari B, Cairns MJ. Khavari B, et al. Cells. 2020 Aug 5;9(8):1837. doi: 10.3390/cells9081837. Cells. 2020. PMID: 32764320 Free PMC article. Review.
Schizophrenia is a severe psychiatric disorder with a complex array of signs and symptoms that causes very significant disability in young people. While schizophrenia has a strong genetic component, with heritability around 80%, there is also a very significant rang
Schizophrenia is a severe psychiatric disorder with a complex array of signs and symptoms that causes very significant disability in
[Schizophrenia-associated single nucleotide polymorphisms affecting microRNA function].
Liang WQ, Hou Y, Zhao CY. Liang WQ, et al. Yi Chuan. 2019 Aug 20;41(8):677-685. doi: 10.16288/j.yczz.19-126. Yi Chuan. 2019. PMID: 31447419 Review. Chinese.
Recent genome-wide association studies (GWAS) find most of schizophrenia-associated single nucleotide polymorphisms (SNPs) locating in the non-coding regions, providing functional implications of miRNAs in the development of schizophrenia. ...We also speculate on th …
Recent genome-wide association studies (GWAS) find most of schizophrenia-associated single nucleotide polymorphisms (SNPs) locating i …
The emerging role of MicroRNA in schizophrenia.
Caputo V, Ciolfi A, Macri S, Pizzuti A. Caputo V, et al. CNS Neurol Disord Drug Targets. 2015;14(2):208-21. doi: 10.2174/1871527314666150116124253. CNS Neurol Disord Drug Targets. 2015. PMID: 25613509 Review.
MicroRNAs (miRNAs) are ~22 nucleotide non-coding RNAs that control gene expression post-transcriptionally by base pairing to mRNAs. ...In this review we summarize the most significant results of experimental studies aimed at highlighting the involvement of human miRNAs in
MicroRNAs (miRNAs) are ~22 nucleotide non-coding RNAs that control gene expression post-transcriptionally by base pairing to mRNAs. .
Mendelian randomization reveals the causal links between microRNA and schizophrenia.
Mu C, Dang X, Luo XJ. Mu C, et al. J Psychiatr Res. 2023 Jul;163:372-377. doi: 10.1016/j.jpsychires.2023.05.071. Epub 2023 May 26. J Psychiatr Res. 2023. PMID: 37267734
MicroRNAs have pivotal roles in gene regulation. However, microRNAs that have causal effects on schizophrenia remain largely unknown. ...This MR study identified six microRNAs whose genetically regulated expression might have a causal role in schizo
MicroRNAs have pivotal roles in gene regulation. However, microRNAs that have causal effects on schizophrenia remain la
Neuroepigenetics of Schizophrenia.
Punzi G, Bharadwaj R, Ursini G. Punzi G, et al. Prog Mol Biol Transl Sci. 2018;158:195-226. doi: 10.1016/bs.pmbts.2018.04.010. Epub 2018 Jun 11. Prog Mol Biol Transl Sci. 2018. PMID: 30072054 Review.
Schizophrenia is a complex disorder of the brain, where genetic variants explain only a portion of risk. ...Non-coding RNAs provide a novel and complex mechanism of gene regulation potentially significant for schizophrenia, as proposed by research on specific mic
Schizophrenia is a complex disorder of the brain, where genetic variants explain only a portion of risk. ...Non-coding RNAs provide a
MicroRNA-195 predicts olanzapine response in drug-free patients with schizophrenia: A prospective cohort study.
Huang X, Bao C, Lv Q, Zhao J, Hu G, Wu H, Li Z, Yi Z. Huang X, et al. J Psychopharmacol. 2021 Jan;35(1):23-30. doi: 10.1177/0269881120959617. Epub 2020 Dec 4. J Psychopharmacol. 2021. PMID: 33274684
BACKGROUND: Disturbances of microRNA-195 have been implicated in the pathogenesis of schizophrenia. However, microRNA-195 levels in schizophrenia are controversial. AIMS: To the best of our knowledge, this is the first study to examine microRNA- …
BACKGROUND: Disturbances of microRNA-195 have been implicated in the pathogenesis of schizophrenia. However, microRNA-1 …
593 results