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Items: 1 to 20 of 197


HLA-Shared Epitope, Inflammation, Mortality, CVD and Malignancy Among Postmenopausal Women With and Without Rheumatoid Arthritis in the Women's Health.

Birru Talabi M, Mackey RH, Kuller LH, Dorman JS, Deane KD, Robinson WH, Walitt BT, Chang Y, Holers VM, Liu S, Moreland LW.

Am J Epidemiol. 2017 Apr 28. doi: 10.1093/aje/kwx087. [Epub ahead of print]


In Vitro and In Vivo Differences in Murine Third Complement Component (C3) Opsonization and Macrophage/Leukocyte Responses to Antibody-Functionalized Iron Oxide Nanoworms.

Wang G, Griffin JI, Inturi S, Brenneman B, Banda NK, Holers VM, Moghimi SM, Simberg D.

Front Immunol. 2017 Feb 15;8:151. doi: 10.3389/fimmu.2017.00151. eCollection 2017.


Editorial: Prevention of Rheumatoid Arthritis: Now Is the Time, but How to Proceed?

Deane KD, Striebich CC, Holers VM.

Arthritis Rheumatol. 2017 May;69(5):873-877. doi: 10.1002/art.40061. Epub 2017 Apr 11. No abstract available.


Anti-Citrullinated Protein Antibodies Are Associated With Neutrophil Extracellular Traps in the Sputum in Relatives of Rheumatoid Arthritis Patients.

Demoruelle MK, Harrall KK, Ho L, Purmalek MM, Seto NL, Rothfuss HM, Weisman MH, Solomon JJ, Fischer A, Okamoto Y, Kelmenson LB, Parish MC, Feser M, Fleischer C, Anderson C, Mahler M, Norris JM, Kaplan MJ, Cherrington BD, Holers VM, Deane KD.

Arthritis Rheumatol. 2017 Feb 9. doi: 10.1002/art.40066. [Epub ahead of print]


Complement proteins bind to nanoparticle protein corona and undergo dynamic exchange in vivo.

Chen F, Wang G, Griffin JI, Brenneman B, Banda NK, Holers VM, Backos DS, Wu L, Moghimi SM, Simberg D.

Nat Nanotechnol. 2017 May;12(4):387-393. doi: 10.1038/nnano.2016.269. Epub 2016 Dec 19.


Mapping the Complement Factor H-Related Protein 1 (CFHR1):C3b/C3d Interactions.

Hannan JP, Laskowski J, Thurman JM, Hageman GS, Holers VM.

PLoS One. 2016 Nov 4;11(11):e0166200. doi: 10.1371/journal.pone.0166200. eCollection 2016.


A molecular signature of preclinical rheumatoid arthritis triggered by dysregulated PTPN22.

Chang HH, Liu GY, Dwivedi N, Sun B, Okamoto Y, Kinslow JD, Deane KD, Demoruelle MK, Norris JM, Thompson PR, Sparks JA, Rao DA, Karlson EW, Hung HC, Holers VM, Ho IC.

JCI Insight. 2016 Oct 20;1(17):e90045.


Activation of Human Complement System by Dextran-Coated Iron Oxide Nanoparticles Is Not Affected by Dextran/Fe Ratio, Hydroxyl Modifications, and Crosslinking.

Wang G, Chen F, Banda NK, Holers VM, Wu L, Moghimi SM, Simberg D.

Front Immunol. 2016 Oct 10;7:418. eCollection 2016.


Mannan-Binding Lectin-Associated Serine Protease 1/3 Cleavage of Pro-Factor D into Factor D In Vivo and Attenuation of Collagen Antibody-Induced Arthritis through Their Targeted Inhibition by RNA Interference-Mediated Gene Silencing.

Banda NK, Acharya S, Scheinman RI, Mehta G, Coulombe M, Takahashi M, Sekine H, Thiel S, Fujita T, Holers VM.

J Immunol. 2016 Nov 1;197(9):3680-3694. Epub 2016 Oct 5.


New therapeutic and diagnostic opportunities for injured tissue-specific targeting of complement inhibitors and imaging modalities.

Holers VM, Tomlinson S, Kulik L, Atkinson C, Rohrer B, Banda N, Thurman JM.

Semin Immunol. 2016 Jun;28(3):260-7. doi: 10.1016/j.smim.2016.05.007. Epub 2016 Jun 6. Review.


Elevated IgA Plasmablast Levels in Subjects at Risk of Developing Rheumatoid Arthritis.

Kinslow JD, Blum LK, Deane KD, Demoruelle MK, Okamoto Y, Parish MC, Kongpachith S, Lahey LJ, Norris JM, Robinson WH, Holers VM.

Arthritis Rheumatol. 2016 Oct;68(10):2372-83. doi: 10.1002/art.39771.


Omega-3 fatty acids are associated with a lower prevalence of autoantibodies in shared epitope-positive subjects at risk for rheumatoid arthritis.

Gan RW, Demoruelle MK, Deane KD, Weisman MH, Buckner JH, Gregersen PK, Mikuls TR, O'Dell JR, Keating RM, Fingerlin TE, Zerbe GO, Clare-Salzler MJ, Holers VM, Norris JM.

Ann Rheum Dis. 2017 Jan;76(1):147-152. doi: 10.1136/annrheumdis-2016-209154. Epub 2016 May 17.


Distinct roles for the complement regulators factor H and Crry in protection of the kidney from injury.

Laskowski J, Renner B, Le Quintrec M, Panzer S, Hannan JP, Ljubanovic D, Ruseva MM, Borza DB, Antonioli AH, Pickering MC, Holers VM, Thurman JM.

Kidney Int. 2016 Jul;90(1):109-22. doi: 10.1016/j.kint.2016.02.036. Epub 2016 May 7.


Site-targeted complement inhibition by a complement receptor 2-conjugated inhibitor (mTT30) ameliorates post-injury neuropathology in mouse brains.

Rich MC, Keene CN, Neher MD, Johnson K, Yu ZX, Ganivet A, Holers VM, Stahel PF.

Neurosci Lett. 2016 Mar 23;617:188-94. doi: 10.1016/j.neulet.2016.02.025. Epub 2016 Feb 15.


Associations of Smoking and Age With Inflammatory Joint Signs Among Unaffected First-Degree Relatives of Rheumatoid Arthritis Patients: Results From Studies of the Etiology of Rheumatoid Arthritis.

Sparks JA, Chang SC, Deane KD, Gan RW, Kristen Demoruelle M, Feser ML, Moss L, Buckner JH, Keating RM, Costenbader KH, Gregersen PK, Weisman MH, Mikuls TR, O'Dell JR, Michael Holers V, Norris JM, Karlson EW.

Arthritis Rheumatol. 2016 Aug;68(8):1828-38. doi: 10.1002/art.39630.


Annexin A2 Enhances Complement Activation by Inhibiting Factor H.

Renner B, Tong HH, Laskowski J, Jonscher K, Goetz L, Woolaver R, Hannan J, Li YX, Hourcade D, Pickering MC, Holers VM, Thurman JM.

J Immunol. 2016 Feb 1;196(3):1355-65. doi: 10.4049/jimmunol.1500793. Epub 2016 Jan 4.


The relationship of circulating proteins in early pregnancy with preterm birth.

Lynch AM, Wagner BD, Deterding RR, Giclas PC, Gibbs RS, Janoff EN, Holers VM, Santoro NF.

Am J Obstet Gynecol. 2016 Apr;214(4):517.e1-8. doi: 10.1016/j.ajog.2015.11.001. Epub 2015 Nov 11.


The Relationship of Longitudinal Levels of Complement Bb During Pregnancy with Preeclampsia.

Lynch AM, Wagner BD, Giclas PC, West NA, Gibbs RS, Holers VM.

Am J Reprod Immunol. 2016 Feb;75(2):104-11. doi: 10.1111/aji.12439. Epub 2015 Oct 29.


Modulatory Role of Surface Coating of Superparamagnetic Iron Oxide Nanoworms in Complement Opsonization and Leukocyte Uptake.

Inturi S, Wang G, Chen F, Banda NK, Holers VM, Wu L, Moghimi SM, Simberg D.

ACS Nano. 2015 Nov 24;9(11):10758-68. doi: 10.1021/acsnano.5b05061. Epub 2015 Oct 21.


Lower omega-3 fatty acids are associated with the presence of anti-cyclic citrullinated peptide autoantibodies in a population at risk for future rheumatoid arthritis: a nested case-control study.

Gan RW, Young KA, Zerbe GO, Demoruelle MK, Weisman MH, Buckner JH, Gregersen PK, Mikuls TR, O'Dell JR, Keating RM, Clare-Salzler MJ, Deane KD, Holers VM, Norris JM.

Rheumatology (Oxford). 2016 Feb;55(2):367-76. doi: 10.1093/rheumatology/kev266. Epub 2015 Sep 13.

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