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Items: 1 to 20 of 307


Synthetic Circular RNA Functions as a miR-21 Sponge to Suppress Gastric Carcinoma Cell Proliferation.

Liu X, Abraham JM, Cheng Y, Wang Z, Wang Z, Zhang G, Ashktorab H, Smoot DT, Cole RN, Boronina TN, DeVine LR, Talbot CC Jr, Liu Z, Meltzer SJ.

Mol Ther Nucleic Acids. 2018 Sep 22;13:312-321. doi: 10.1016/j.omtn.2018.09.010. [Epub ahead of print]


Modeling Wnt signaling by CRISPR-Cas9 genome editing recapitulates neoplasia in human Barrett epithelial organoids.

Liu X, Cheng Y, Abraham JM, Wang Z, Wang Z, Ke X, Yan R, Shin EJ, Ngamruengphong S, Khashab MA, Zhang G, McNamara G, Ewald AJ, Lin D, Liu Z, Meltzer SJ.

Cancer Lett. 2018 Nov 1;436:109-118. doi: 10.1016/j.canlet.2018.08.017. Epub 2018 Aug 23.


Inhibition of the miR-192/215-Rab11-FIP2 axis suppresses human gastric cancer progression.

Zhang X, Peng Y, Huang Y, Deng S, Feng X, Hou G, Lin H, Wang J, Yan R, Zhao Y, Fan X, Meltzer SJ, Li S, Jin Z.

Cell Death Dis. 2018 Jul 13;9(7):778. doi: 10.1038/s41419-018-0785-5.


Super-Enhancer-Driven Long Non-Coding RNA LINC01503, Regulated by TP63, Is Over-Expressed and Oncogenic in Squamous Cell Carcinoma.

Xie JJ, Jiang YY, Jiang Y, Li CQ, Lim MC, An O, Mayakonda A, Ding LW, Long L, Sun C, Lin LH, Chen L, Wu JY, Wu ZY, Cao Q, Fang WK, Yang W, Soukiasian H, Meltzer SJ, Yang H, Fullwood M, Xu LY, Li EM, Lin DC, Koeffler HP.

Gastroenterology. 2018 Jun;154(8):2137-2151.e1. doi: 10.1053/j.gastro.2018.02.018. Epub 2018 Feb 15.


SMG-1 inhibition by miR-192/-215 causes epithelial-mesenchymal transition in gastric carcinogenesis via activation of Wnt signaling.

Zhang X, Peng Y, Huang Y, Yang M, Yan R, Zhao Y, Cheng Y, Liu X, Deng S, Feng X, Lin H, Yu H, Chen S, Zhao Z, Li S, Li K, Wang L, Wei Y, He Z, Fan X, Meltzer SJ, Li S, Jin Z.

Cancer Med. 2018 Jan;7(1):146-156. doi: 10.1002/cam4.1237. Epub 2017 Dec 13.


Esophageal Adenocarcinoma-Derived Extracellular Vesicle MicroRNAs Induce a Neoplastic Phenotype in Gastric Organoids.

Ke X, Yan R, Sun Z, Cheng Y, Meltzer A, Lu N, Shu X, Wang Z, Huang B, Liu X, Wang Z, Song JH, Ng CK, Ibrahim S, Abraham JM, Shin EJ, He S, Meltzer SJ.

Neoplasia. 2017 Nov;19(11):941-949. doi: 10.1016/j.neo.2017.06.007. Epub 2017 Sep 29.


Determination of absolute expression profiles using multiplexed miRNA analysis.

Song Y, Kilburn D, Song JH, Cheng Y, Saeui CT, Cheung DG, Croce CM, Yarema KJ, Meltzer SJ, Liu KJ, Wang TH.

PLoS One. 2017 Jul 13;12(7):e0180988. doi: 10.1371/journal.pone.0180988. eCollection 2017.


RNA sequencing of esophageal adenocarcinomas identifies novel fusion transcripts, including NPC1-MELK, arising from a complex chromosomal rearrangement.

Wang Z, Cheng Y, Abraham JM, Yan R, Liu X, Chen W, Ibrahim S, Schroth GP, Ke X, He Y, Meltzer SJ.

Cancer. 2017 Oct 15;123(20):3916-3924. doi: 10.1002/cncr.30837. Epub 2017 Jun 22.


Nearly a Third of High-Grade Dysplasia and Colorectal Cancer Is Undetected in Patients with Inflammatory Bowel Disease.

Eluri S, Parian AM, Limketkai BN, Ha CY, Brant SR, Dudley-Brown S, Efron JE, Fang SG, Gearhart SL, Marohn MR, Meltzer SJ, Bashar S, Truta B, Montgomery EA, Lazarev MG.

Dig Dis Sci. 2017 Dec;62(12):3586-3593. doi: 10.1007/s10620-017-4652-5. Epub 2017 Jun 19.


Long Noncoding RNAs in the Pathogenesis of Barrett's Esophagus and Esophageal Carcinoma.

Abraham JM, Meltzer SJ.

Gastroenterology. 2017 Jul;153(1):27-34. doi: 10.1053/j.gastro.2017.04.046. Epub 2017 May 18. Review.


Gastric Cancer in the Era of Precision Medicine.

Liu X, Meltzer SJ.

Cell Mol Gastroenterol Hepatol. 2017 Feb 20;3(3):348-358. doi: 10.1016/j.jcmgh.2017.02.003. eCollection 2017 May. Review.


Radiofrequency Ablation of Barrett's Esophagus Reduces Esophageal Adenocarcinoma Incidence and Mortality in a Comparative Modeling Analysis.

Kroep S, Heberle CR, Curtius K, Kong CY, Lansdorp-Vogelaar I, Ali A, Wolf WA, Shaheen NJ, Spechler SJ, Rubenstein JH, Nishioka NS, Meltzer SJ, Hazelton WD, van Ballegooijen M, Tramontano AC, Gazelle GS, Luebeck EG, Inadomi JM, Hur C.

Clin Gastroenterol Hepatol. 2017 Sep;15(9):1471-1474. doi: 10.1016/j.cgh.2016.12.034. Epub 2017 Jan 12. No abstract available.


The novel fusion transcript NR5A2-KLHL29FT is generated by an insertion at the KLHL29 locus.

Sun Z, Ke X, Salzberg SL, Kim D, Antonescu V, Cheng Y, Huang B, Song JH, Abraham JM, Ibrahim S, Tian H, Meltzer SJ.

Cancer. 2017 May 1;123(9):1507-1515. doi: 10.1002/cncr.30510. Epub 2017 Jan 12.


Proton Pump Inhibitors Do Not Reduce the Risk of Esophageal Adenocarcinoma in Patients with Barrett's Esophagus: A Systematic Review and Meta-Analysis.

Hu Q, Sun TT, Hong J, Fang JY, Xiong H, Meltzer SJ.

PLoS One. 2017 Jan 10;12(1):e0169691. doi: 10.1371/journal.pone.0169691. eCollection 2017. Review.


MiRNA-194 activates the Wnt/β-catenin signaling pathway in gastric cancer by targeting the negative Wnt regulator, SUFU.

Peng Y, Zhang X, Ma Q, Yan R, Qin Y, Zhao Y, Cheng Y, Yang M, Wang Q, Feng X, Huang Y, Huang W, Zhao Z, Wang L, Wei Y, He Z, Fan X, Li S, Jin Z, Meltzer SJ.

Cancer Lett. 2017 Jan 28;385:117-127. doi: 10.1016/j.canlet.2016.10.035. Epub 2016 Oct 31.


Paf15 expression correlates with rectal cancer prognosis, cell proliferation and radiation response.

Yan R, Zhu K, Dang C, Lan K, Wang H, Yuan D, Chen W, Meltzer SJ, Li K.

Oncotarget. 2016 Jun 21;7(25):38750-38761. doi: 10.18632/oncotarget.9606.


Leaky transporters and sphincters in Barrett's oesophagus?

Meltzer SJ.

Lancet Oncol. 2016 Oct;17(10):1336-1337. doi: 10.1016/S1470-2045(16)30365-5. Epub 2016 Aug 12. No abstract available.


Extracellular vesicles carry microRNA-195 to intrahepatic cholangiocarcinoma and improve survival in a rat model.

Li L, Piontek K, Ishida M, Fausther M, Dranoff JA, Fu R, Mezey E, Gould SJ, Fordjour FK, Meltzer SJ, Sirica AE, Selaru FM.

Hepatology. 2017 Feb;65(2):501-514. doi: 10.1002/hep.28735. Epub 2016 Aug 29.


TNFAIP8 overexpression: a potential predictor of lymphatic metastatic recurrence in pN0 esophageal squamous cell carcinoma after Ivor Lewis esophagectomy.

Sun Z, Liu X, Song JH, Cheng Y, Liu Y, Jia Y, Meltzer SJ, Wang Z.

Tumour Biol. 2016 Aug;37(8):10923-34. doi: 10.1007/s13277-016-4978-1. Epub 2016 Feb 17.


Long non-coding antisense RNA KRT7-AS is activated in gastric cancers and supports cancer cell progression by increasing KRT7 expression.

Huang B, Song JH, Cheng Y, Abraham JM, Ibrahim S, Sun Z, Ke X, Meltzer SJ.

Oncogene. 2016 Sep 15;35(37):4927-36. doi: 10.1038/onc.2016.25. Epub 2016 Feb 15.

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