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Items: 18

1.

Long noncoding RNAs as regulators of Toll-like receptor signaling and innate immunity.

Murphy MB, Medvedev AE.

J Leukoc Biol. 2016 Jun;99(6):839-50. doi: 10.1189/jlb.2RU1215-575R. Review.

PMID:
26965636
2.

Endotoxin Tolerance Inhibits Lyn and c-Src Phosphorylation and Association with Toll-Like Receptor 4 but Increases Expression and Activity of Protein Phosphatases.

Xiong Y, Murphy M, Manavalan TT, Pattabiraman G, Qiu F, Chang HH, Ho IC, Medvedev AE.

J Innate Immun. 2016;8(2):171-84. doi: 10.1159/000440838.

3.

Pellino-3 promotes endotoxin tolerance and acts as a negative regulator of TLR2 and TLR4 signaling.

Murphy MB, Xiong Y, Pattabiraman G, Manavalan TT, Qiu F, Medvedev AE.

J Leukoc Biol. 2015 Dec;98(6):963-74. doi: 10.1189/jlb.2VMA0515-229RR.

4.

Pellino-1 Positively Regulates Toll-like Receptor (TLR) 2 and TLR4 Signaling and Is Suppressed upon Induction of Endotoxin Tolerance.

Murphy M, Xiong Y, Pattabiraman G, Qiu F, Medvedev AE.

J Biol Chem. 2015 Jul 31;290(31):19218-32. doi: 10.1074/jbc.M115.640128.

5.

IRAK4 kinase activity is not required for induction of endotoxin tolerance but contributes to TLR2-mediated tolerance.

Xiong Y, Pennini M, Vogel SN, Medvedev AE.

J Leukoc Biol. 2013 Aug;94(2):291-300. doi: 10.1189/jlb.0812401.

6.
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Endotoxin tolerance dysregulates MyD88- and Toll/IL-1R domain-containing adapter inducing IFN-beta-dependent pathways and increases expression of negative regulators of TLR signaling.

Piao W, Song C, Chen H, Diaz MA, Wahl LM, Fitzgerald KA, Li L, Medvedev AE.

J Leukoc Biol. 2009 Oct;86(4):863-75. doi: 10.1189/jlb.0309189.

9.

Tyrosine phosphorylation of MyD88 adapter-like (Mal) is critical for signal transduction and blocked in endotoxin tolerance.

Piao W, Song C, Chen H, Wahl LM, Fitzgerald KA, O'Neill LA, Medvedev AE.

J Biol Chem. 2008 Feb 8;283(6):3109-19.

11.

Role of TLR4 tyrosine phosphorylation in signal transduction and endotoxin tolerance.

Medvedev AE, Piao W, Shoenfelt J, Rhee SH, Chen H, Basu S, Wahl LM, Fenton MJ, Vogel SN.

J Biol Chem. 2007 Jun 1;282(22):16042-53.

12.

Tolerance to microbial TLR ligands: molecular mechanisms and relevance to disease.

Medvedev AE, Sabroe I, Hasday JD, Vogel SN.

J Endotoxin Res. 2006;12(3):133-50. Review.

PMID:
16719986
13.
14.

Induction of in vitro reprogramming by Toll-like receptor (TLR)2 and TLR4 agonists in murine macrophages: effects of TLR "homotolerance" versus "heterotolerance" on NF-kappa B signaling pathway components.

Dobrovolskaia MA, Medvedev AE, Thomas KE, Cuesta N, Toshchakov V, Ren T, Cody MJ, Michalek SM, Rice NR, Vogel SN.

J Immunol. 2003 Jan 1;170(1):508-19.

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Induction of tolerance to lipopolysaccharide and mycobacterial components in Chinese hamster ovary/CD14 cells is not affected by overexpression of Toll-like receptors 2 or 4.

Medvedev AE, Henneke P, Schromm A, Lien E, Ingalls R, Fenton MJ, Golenbock DT, Vogel SN.

J Immunol. 2001 Aug 15;167(4):2257-67.

18.

[Study of the action of tumor cell immunosuppressive factors on the production of cytokines by lymphocytes and macrophages and the mitogenic activity of interleukin-2].

Medvedev AE, Fuks BB, Iuriants K, Dostman U, Flegel' A.

Biull Eksp Biol Med. 1991 May;111(5):523-5. Russian.

PMID:
1878570
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