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Items: 18

1.

Long noncoding RNAs as regulators of Toll-like receptor signaling and innate immunity.

Murphy MB, Medvedev AE.

J Leukoc Biol. 2016 Jun;99(6):839-50. doi: 10.1189/jlb.2RU1215-575R. Epub 2016 Mar 10. Review.

PMID:
26965636
2.

Endotoxin Tolerance Inhibits Lyn and c-Src Phosphorylation and Association with Toll-Like Receptor 4 but Increases Expression and Activity of Protein Phosphatases.

Xiong Y, Murphy M, Manavalan TT, Pattabiraman G, Qiu F, Chang HH, Ho IC, Medvedev AE.

J Innate Immun. 2016;8(2):171-84. doi: 10.1159/000440838. Epub 2015 Oct 13.

3.

Pellino-3 promotes endotoxin tolerance and acts as a negative regulator of TLR2 and TLR4 signaling.

Murphy MB, Xiong Y, Pattabiraman G, Manavalan TT, Qiu F, Medvedev AE.

J Leukoc Biol. 2015 Dec;98(6):963-74. doi: 10.1189/jlb.2VMA0515-229RR. Epub 2015 Aug 26.

4.

Pellino-1 Positively Regulates Toll-like Receptor (TLR) 2 and TLR4 Signaling and Is Suppressed upon Induction of Endotoxin Tolerance.

Murphy M, Xiong Y, Pattabiraman G, Qiu F, Medvedev AE.

J Biol Chem. 2015 Jul 31;290(31):19218-32. doi: 10.1074/jbc.M115.640128. Epub 2015 Jun 16.

5.

IRAK4 kinase activity is not required for induction of endotoxin tolerance but contributes to TLR2-mediated tolerance.

Xiong Y, Pennini M, Vogel SN, Medvedev AE.

J Leukoc Biol. 2013 Aug;94(2):291-300. doi: 10.1189/jlb.0812401. Epub 2013 May 21.

6.

Induction of endotoxin tolerance in vivo inhibits activation of IRAK4 and increases negative regulators IRAK-M, SHIP-1, and A20.

Xiong Y, Medvedev AE.

J Leukoc Biol. 2011 Dec;90(6):1141-8. doi: 10.1189/jlb.0611273. Epub 2011 Sep 20.

8.

Endotoxin tolerance dysregulates MyD88- and Toll/IL-1R domain-containing adapter inducing IFN-beta-dependent pathways and increases expression of negative regulators of TLR signaling.

Piao W, Song C, Chen H, Diaz MA, Wahl LM, Fitzgerald KA, Li L, Medvedev AE.

J Leukoc Biol. 2009 Oct;86(4):863-75. doi: 10.1189/jlb.0309189. Epub 2009 Aug 5.

9.

Tyrosine phosphorylation of MyD88 adapter-like (Mal) is critical for signal transduction and blocked in endotoxin tolerance.

Piao W, Song C, Chen H, Wahl LM, Fitzgerald KA, O'Neill LA, Medvedev AE.

J Biol Chem. 2008 Feb 8;283(6):3109-19. Epub 2007 Dec 10.

11.

Role of TLR4 tyrosine phosphorylation in signal transduction and endotoxin tolerance.

Medvedev AE, Piao W, Shoenfelt J, Rhee SH, Chen H, Basu S, Wahl LM, Fenton MJ, Vogel SN.

J Biol Chem. 2007 Jun 1;282(22):16042-53. Epub 2007 Mar 28.

12.

Tolerance to microbial TLR ligands: molecular mechanisms and relevance to disease.

Medvedev AE, Sabroe I, Hasday JD, Vogel SN.

J Endotoxin Res. 2006;12(3):133-50. Review.

PMID:
16719986
13.
14.

Induction of in vitro reprogramming by Toll-like receptor (TLR)2 and TLR4 agonists in murine macrophages: effects of TLR "homotolerance" versus "heterotolerance" on NF-kappa B signaling pathway components.

Dobrovolskaia MA, Medvedev AE, Thomas KE, Cuesta N, Toshchakov V, Ren T, Cody MJ, Michalek SM, Rice NR, Vogel SN.

J Immunol. 2003 Jan 1;170(1):508-19.

15.
16.

Induction of tolerance to lipopolysaccharide and mycobacterial components in Chinese hamster ovary/CD14 cells is not affected by overexpression of Toll-like receptors 2 or 4.

Medvedev AE, Henneke P, Schromm A, Lien E, Ingalls R, Fenton MJ, Golenbock DT, Vogel SN.

J Immunol. 2001 Aug 15;167(4):2257-67.

18.

[Study of the action of tumor cell immunosuppressive factors on the production of cytokines by lymphocytes and macrophages and the mitogenic activity of interleukin-2].

Medvedev AE, Fuks BB, Iuriants K, Dostman U, Flegel' A.

Biull Eksp Biol Med. 1991 May;111(5):523-5. Russian.

PMID:
1878570

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