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Items: 1 to 20 of 104

1.

Autophagy Is a Potential Target for Enhancing the Anti-Angiogenic Effect of Mebendazole in Endothelial Cells.

Sung SJ, Kim HK, Hong YK, Joe YA.

Biomol Ther (Seoul). 2019 Jan 1;27(1):117-125. doi: 10.4062/biomolther.2018.222.

2.

Bioelectronics of The Cellular Cytoskeleton: Monitoring Cytoskeletal Conductance Variation for Sensing Drug Resistance.

Gharooni M, Alikhani A, Moghtaderi H, Abiri H, Mashaghi A, Abbasvandi F, Khayamian MA, Miripour ZS, Zandi A, Abdolahad M.

ACS Sens. 2019 Feb 22;4(2):353-362. doi: 10.1021/acssensors.8b01142. Epub 2019 Jan 4.

PMID:
30572702
3.

Mebendazole and radiation in combination increase survival through anticancer mechanisms in an intracranial rodent model of malignant meningioma.

Skibinski CG, Williamson T, Riggins GJ.

J Neurooncol. 2018 Dec;140(3):529-538. doi: 10.1007/s11060-018-03009-7. Epub 2018 Nov 9.

PMID:
30414098
4.

Mebendazole Potentiates Radiation Therapy in Triple-Negative Breast Cancer.

Zhang L, Bochkur Dratver M, Yazal T, Dong K, Nguyen A, Yu G, Dao A, Bochkur Dratver M, Duhachek-Muggy S, Bhat K, Alli C, Pajonk F, Vlashi E.

Int J Radiat Oncol Biol Phys. 2019 Jan 1;103(1):195-207. doi: 10.1016/j.ijrobp.2018.08.046. Epub 2018 Sep 7.

PMID:
30196056
5.

Mebendazole stimulates CD14+ myeloid cells to enhance T-cell activation and tumour cell killing.

Rubin J, Mansoori S, Blom K, Berglund M, Lenhammar L, Andersson C, Loskog A, Fryknäs M, Nygren P, Larsson R.

Oncotarget. 2018 Jul 20;9(56):30805-30813. doi: 10.18632/oncotarget.25713. eCollection 2018 Jul 20.

6.

Flubendazole and mebendazole impair migration and epithelial to mesenchymal transition in oral cell lines.

Kralova V, Hanušová V, Caltová K, Špaček P, Hochmalová M, Skálová L, Rudolf E.

Chem Biol Interact. 2018 Sep 25;293:124-132. doi: 10.1016/j.cbi.2018.07.026. Epub 2018 Jul 31.

PMID:
30075109
7.

Flubendazole elicits anti-metastatic effects in triple-negative breast cancer via STAT3 inhibition.

Oh E, Kim YJ, An H, Sung D, Cho TM, Farrand L, Jang S, Seo JH, Kim JY.

Int J Cancer. 2018 Oct 15;143(8):1978-1993. doi: 10.1002/ijc.31585. Epub 2018 Jul 10.

PMID:
29744876
8.

N-Substituted Prodrugs of Mebendazole Provide Improved Aqueous Solubility and Oral Bioavailability in Mice and Dogs.

Zimmermann SC, Tichý T, Vávra J, Dash RP, Slusher CE, Gadiano AJ, Wu Y, Jančařík A, Tenora L, Monincová L, Prchalová E, Riggins GJ, Majer P, Slusher BS, Rais R.

J Med Chem. 2018 May 10;61(9):3918-3929. doi: 10.1021/acs.jmedchem.7b01792. Epub 2018 Apr 19.

PMID:
29648826
9.

Evaluation of kinase-inhibitors nilotinib and everolimus against alveolar echinococcosis in vitro and in a mouse model.

Joekel DE, Lundström-Stadelmann B, Müllhaupt B, Hemphill A, Deplazes P.

Exp Parasitol. 2018 May;188:65-72. doi: 10.1016/j.exppara.2018.04.002. Epub 2018 Apr 3.

PMID:
29625098
10.

Discovery of genomic intervals that underlie nematode responses to benzimidazoles.

Zamanian M, Cook DE, Zdraljevic S, Brady SC, Lee D, Lee J, Andersen EC.

PLoS Negl Trop Dis. 2018 Mar 30;12(3):e0006368. doi: 10.1371/journal.pntd.0006368. eCollection 2018 Mar.

11.

Systematic identification of suspected anthelmintic benzimidazole metabolites using LC-MS/MS.

Majewsky M, Castel D, Le Dret L, Johann P, Jones DT, Pfister SM, Haefeli WE, Burhenne J.

J Pharm Biomed Anal. 2018 Mar 20;151:151-158. doi: 10.1016/j.jpba.2017.12.056. Epub 2017 Dec 28.

PMID:
29328982
12.

Microtubule-targeting agents can sensitize cancer cells to ionizing radiation by an interphase-based mechanism.

Markowitz D, Ha G, Ruggieri R, Symons M.

Onco Targets Ther. 2017 Nov 24;10:5633-5642. doi: 10.2147/OTT.S143096. eCollection 2017.

13.

Flubendazole induces mitotic catastrophe and apoptosis in melanoma cells.

Čáňová K, Rozkydalová L, Vokurková D, Rudolf E.

Toxicol In Vitro. 2018 Feb;46:313-322. doi: 10.1016/j.tiv.2017.10.025. Epub 2017 Oct 26.

PMID:
29107018
14.

Targeting acute myeloid leukemia by drug-induced c-MYB degradation.

Walf-Vorderwülbecke V, Pearce K, Brooks T, Hubank M, van den Heuvel-Eibrink MM, Zwaan CM, Adams S, Edwards D, Bartram J, Samarasinghe S, Ancliff P, Khwaja A, Goulden N, Williams G, de Boer J, Williams O.

Leukemia. 2018 Apr;32(4):882-889. doi: 10.1038/leu.2017.317. Epub 2017 Nov 1.

PMID:
29089643
15.

Flubendazole overcomes trastuzumab resistance by targeting cancer stem-like properties and HER2 signaling in HER2-positive breast cancer.

Kim YJ, Sung D, Oh E, Cho Y, Cho TM, Farrand L, Seo JH, Kim JY.

Cancer Lett. 2018 Jan 1;412:118-130. doi: 10.1016/j.canlet.2017.10.020. Epub 2017 Nov 5.

PMID:
29080749
16.

Vinblastine and antihelmintic mebendazole potentiate temozolomide in resistant gliomas.

Kipper FC, Silva AO, Marc AL, Confortin G, Junqueira AV, Neto EP, Lenz G.

Invest New Drugs. 2018 Apr;36(2):323-331. doi: 10.1007/s10637-017-0503-7. Epub 2017 Aug 29.

PMID:
28852916
17.

Mebendazole, an antiparasitic drug, inhibits drug transporters expression in preclinical model of gastric peritoneal carcinomatosis.

Celestino Pinto L, de Fátima Aquino Moreira-Nunes C, Soares BM, Burbano RMR, de Lemos JAR, Montenegro RC.

Toxicol In Vitro. 2017 Sep;43:87-91. doi: 10.1016/j.tiv.2017.06.007. Epub 2017 Jun 9.

18.

Bioelectrical impedimetric sensor for single cell analysis based on nanoroughened quartz substrate; suitable for cancer therapeutic purposes.

Gharooni M, Abdolahad M.

J Pharm Biomed Anal. 2017 Aug 5;142:315-323. doi: 10.1016/j.jpba.2017.05.024. Epub 2017 May 15.

PMID:
28531834
19.

The anticancer effect of mebendazole may be due to M1 monocyte/macrophage activation via ERK1/2 and TLR8-dependent inflammasome activation.

Blom K, Senkowski W, Jarvius M, Berglund M, Rubin J, Lenhammar L, Parrow V, Andersson C, Loskog A, Fryknäs M, Nygren P, Larsson R.

Immunopharmacol Immunotoxicol. 2017 Aug;39(4):199-210. doi: 10.1080/08923973.2017.1320671. Epub 2017 May 4.

PMID:
28472897
20.

Anthelmintic Flubendazole and Its Potential Use in Anticancer Therapy.

Čáňová K, Rozkydalová L, Rudolf E.

Acta Medica (Hradec Kralove). 2017;60(1):5-11. doi: 10.14712/18059694.2017.44. Epub 2017 Apr 11. Review.

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