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Items: 1 to 20 of 26


Isothermal titration calorimetry and vesicle leakage assays highlight the differential behaviors of tau repeat segments upon interaction with anionic lipid membranes.

Dicke SS, Tatge L, Engen PE, Culp M, Masterson LR.

Biochem Biophys Res Commun. 2017 Oct 3. pii: S0006-291X(17)31969-1. doi: 10.1016/j.bbrc.2017.10.007. [Epub ahead of print]


Dysfunctional conformational dynamics of protein kinase A induced by a lethal mutant of phospholamban hinder phosphorylation.

Kim J, Masterson LR, Cembran A, Verardi R, Shi L, Gao J, Taylor SS, Veglia G.

Proc Natl Acad Sci U S A. 2015 Mar 24;112(12):3716-21. doi: 10.1073/pnas.1502299112. Epub 2015 Mar 9.


Synchronous opening and closing motions are essential for cAMP-dependent protein kinase A signaling.

Srivastava AK, McDonald LR, Cembran A, Kim J, Masterson LR, McClendon CL, Taylor SS, Veglia G.

Structure. 2014 Dec 2;22(12):1735-43. doi: 10.1016/j.str.2014.09.010. Epub 2014 Nov 6.


Structure and dynamics of a primordial catalytic fold generated by in vitro evolution.

Chao FA, Morelli A, Haugner JC 3rd, Churchfield L, Hagmann LN, Shi L, Masterson LR, Sarangi R, Veglia G, Seelig B.

Nat Chem Biol. 2013 Feb;9(2):81-3. doi: 10.1038/nchembio.1138. Epub 2012 Dec 9.


Conformational equilibrium of N-myristoylated cAMP-dependent protein kinase A by molecular dynamics simulations.

Cembran A, Masterson LR, McClendon CL, Taylor SS, Gao J, Veglia G.

Biochemistry. 2012 Dec 21;51(51):10186-96. doi: 10.1021/bi301279f. Epub 2012 Dec 12.


Isotope labeling for solution and solid-state NMR spectroscopy of membrane proteins.

Verardi R, Traaseth NJ, Masterson LR, Vostrikov VV, Veglia G.

Adv Exp Med Biol. 2012;992:35-62. doi: 10.1007/978-94-007-4954-2_3. Review.


Heteronuclear Adiabatic Relaxation Dispersion (HARD) for quantitative analysis of conformational dynamics in proteins.

Traaseth NJ, Chao FA, Masterson LR, Mangia S, Garwood M, Michaeli S, Seelig B, Veglia G.

J Magn Reson. 2012 Jun;219:75-82. doi: 10.1016/j.jmr.2012.03.024. Epub 2012 Apr 6.


Allostery and binding cooperativity of the catalytic subunit of protein kinase A by NMR spectroscopy and molecular dynamics simulations.

Masterson LR, Cembran A, Shi L, Veglia G.

Adv Protein Chem Struct Biol. 2012;87:363-89. doi: 10.1016/B978-0-12-398312-1.00012-3. Review.


FLAMEnGO: a fuzzy logic approach for methyl group assignment using NOESY and paramagnetic relaxation enhancement data.

Chao FA, Shi L, Masterson LR, Veglia G.

J Magn Reson. 2012 Jan;214(1):103-10. doi: 10.1016/j.jmr.2011.10.008. Epub 2011 Oct 20.


cAMP-dependent protein kinase A selects the excited state of the membrane substrate phospholamban.

Masterson LR, Yu T, Shi L, Wang Y, Gustavsson M, Mueller MM, Veglia G.

J Mol Biol. 2011 Sep 16;412(2):155-64. doi: 10.1016/j.jmb.2011.06.041. Epub 2011 Jul 2.


A myristoyl/phosphoserine switch controls cAMP-dependent protein kinase association to membranes.

Gaffarogullari EC, Masterson LR, Metcalfe EE, Traaseth NJ, Balatri E, Musa MM, Mullen D, Distefano MD, Veglia G.

J Mol Biol. 2011 Aug 26;411(4):823-36. doi: 10.1016/j.jmb.2011.06.034. Epub 2011 Jun 29.


Templating α-amylase peptide inhibitors with organotin compounds.

Porcelli F, Olivieri C, Masterson LR, Wang Y, Veglia G.

J Biol Inorg Chem. 2011 Dec;16(8):1197-204. doi: 10.1007/s00775-011-0808-5. Epub 2011 Jul 7.


Dynamically committed, uncommitted, and quenched states encoded in protein kinase A revealed by NMR spectroscopy.

Masterson LR, Shi L, Metcalfe E, Gao J, Taylor SS, Veglia G.

Proc Natl Acad Sci U S A. 2011 Apr 26;108(17):6969-74. doi: 10.1073/pnas.1102701108. Epub 2011 Apr 6.


Lethal Arg9Cys phospholamban mutation hinders Ca2+-ATPase regulation and phosphorylation by protein kinase A.

Ha KN, Masterson LR, Hou Z, Verardi R, Walsh N, Veglia G, Robia SL.

Proc Natl Acad Sci U S A. 2011 Feb 15;108(7):2735-40. doi: 10.1073/pnas.1013987108. Epub 2011 Jan 31.


Dynamics connect substrate recognition to catalysis in protein kinase A.

Masterson LR, Cheng C, Yu T, Tonelli M, Kornev A, Taylor SS, Veglia G.

Nat Chem Biol. 2010 Nov;6(11):821-8. doi: 10.1038/nchembio.452. Epub 2010 Oct 3. Erratum in: Nat Chem Biol. 2011 May;7(5):319.


One-sample approach to determine the relative orientations of proteins in ternary and binary complexes from residual dipolar coupling measurements.

Tonelli M, Masterson LR, Cornilescu G, Markley JL, Veglia G.

J Am Chem Soc. 2009 Oct 14;131(40):14138-9. doi: 10.1021/ja904766g.


Backbone NMR resonance assignment of the catalytic subunit of cAMP-dependent protein kinase A in complex with AMP-PNP.

Masterson LR, Shi L, Tonelli M, Mascioni A, Mueller MM, Veglia G.

Biomol NMR Assign. 2009 Jun;3(1):115-7. doi: 10.1007/s12104-009-9154-8. Epub 2009 Apr 12.


Pseudoenzymatic dealkylation of alkyltins by biological dithiols.

Porcelli F, Triggiani D, Buck-Koehntop BA, Masterson LR, Veglia G.

J Biol Inorg Chem. 2009 Nov;14(8):1219-25. doi: 10.1007/s00775-009-0565-x. Epub 2009 Jul 21.


Expression and purification of isotopically labeled peptide inhibitors and substrates of cAMP-dependant protein kinase A for NMR analysis.

Masterson LR, Bortone N, Yu T, Ha KN, Gaffarogullari EC, Nguyen O, Veglia G.

Protein Expr Purif. 2009 Apr;64(2):231-6. doi: 10.1016/j.pep.2008.10.016. Epub 2008 Nov 6.


NMR, mass spectrometry and chemical evidence reveal a different chemical structure for methanobactin that contains oxazolone rings.

Behling LA, Hartsel SC, Lewis DE, DiSpirito AA, Choi DW, Masterson LR, Veglia G, Gallagher WH.

J Am Chem Soc. 2008 Sep 24;130(38):12604-5. doi: 10.1021/ja804747d. Epub 2008 Aug 27.

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