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Olig2 positive cells derived from hair follicle neural crest stem cells in rats.
Wang T, Lin H, Liu F, Zhang C. Wang T, et al. J Chem Neuroanat. 2020 Apr;105:101770. doi: 10.1016/j.jchemneu.2020.101770. Epub 2020 Feb 20. J Chem Neuroanat. 2020. PMID: 32088378
In this study, we used the combination of 5 small molecular including CHIR99021 (CHIR), SB431542 (SB), DMH1 (DMH), retinoic acid (RA) and Purmorphamine (Pur) to induce hair follicles neural crest stem cells (hfNCSCs) to motor neurons progenitors (MNPs). ...Nestin, beta-tub …
In this study, we used the combination of 5 small molecular including CHIR99021 (CHIR), SB431542 (SB), DMH1 (DMH), retinoic acid (RA) and …
The Shh coreceptor Cdo is required for differentiation of midbrain dopaminergic neurons.
Kwon YR, Jeong MH, Leem YE, Lee SJ, Kim HJ, Bae GU, Kang JS. Kwon YR, et al. Stem Cell Res. 2014 Sep;13(2):262-74. doi: 10.1016/j.scr.2014.07.004. Epub 2014 Jul 27. Stem Cell Res. 2014. PMID: 25117422 Free article.
In addition, Cdo(-/-) ES cells form fewer tyrosine hydroxylase (TH) and microtubule associated protein 2 (MAP2)-positive DA neurons correlating with the decreased expression of key regulators of DA neurogenesis, such as Shh, Neurogenin2, Mash1, Foxa2, Lmx1a, Nurr1 and Pitx …
In addition, Cdo(-/-) ES cells form fewer tyrosine hydroxylase (TH) and microtubule associated protein 2 (MAP2)-positive DA neurons c …
Directed differentiation of basal forebrain cholinergic neurons from human pluripotent stem cells.
Hu Y, Qu ZY, Cao SY, Li Q, Ma L, Krencik R, Xu M, Liu Y. Hu Y, et al. J Neurosci Methods. 2016 Jun 15;266:42-9. doi: 10.1016/j.jneumeth.2016.03.017. Epub 2016 Mar 29. J Neurosci Methods. 2016. PMID: 27036311
In this method, BFCN progenitors are patterned from hESC or hiPSC-derived primitive neuroepithelial cells, with the treatment of sonic hedgehog (SHH) or combination with its agonist Purmorphamine, and by co-culturing with human astrocytes. RESULTS: At day 20, 90% hPSC-deri …
In this method, BFCN progenitors are patterned from hESC or hiPSC-derived primitive neuroepithelial cells, with the treatment of sonic hedge …